PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT2G20880.1
Common NameAtERF53, ERF053, ERF53, F5H14.15
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 336aa    MW: 38397.7 Da    PI: 6.4126
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT2G20880.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP261.61.7e-19186236256
          AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkklege 56 
                   y+GVr+++ +g+WvAeIr p++   r+r +lg+f+taeeAa a+++ + kl+ge
  AT2G20880.1 186 LYRGVRQRH-WGKWVAEIRKPRN---RTRLWLGTFDTAEEAAMAYDREAFKLRGE 236
                  59******9.**********954...5**************************97 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000183.26E-34185245No hitNo description
SuperFamilySSF541711.63E-23186244IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.101.6E-32186244IPR001471AP2/ERF domain
PROSITE profilePS5103223.235186243IPR001471AP2/ERF domain
SMARTSM003802.8E-41186249IPR001471AP2/ERF domain
PRINTSPR003672.6E-11187198IPR001471AP2/ERF domain
PfamPF008474.3E-14187236IPR001471AP2/ERF domain
PRINTSPR003672.6E-11209225IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009651Biological Processresponse to salt stress
GO:0009873Biological Processethylene-activated signaling pathway
GO:2000070Biological Processregulation of response to water deprivation
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000293anatomyguard cell
PO:0009029anatomystamen
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 336 aa     Download sequence    Send to blast
MATAKNKGKS IRVLGTSEAE KKDEMELEEE FQFSSGKYKD SGPGSDMWLG DASSTSPRSL  60
RKTRTFDRHN PYLVSSYATP QPPTTTTCSV SFPFYLPPAI QNQQRFLHPN DPSGQRQQQM  120
ISFDPQQQVQ PYVAQQQQQQ QHLLQYWRDI LKLSPSGRMM MMNMLRQESD LPLTRPPVQP  180
FSATKLYRGV RQRHWGKWVA EIRKPRNRTR LWLGTFDTAE EAAMAYDREA FKLRGETARL  240
NFPELFLNKQ EPTPVHQKQC ETGTTSEDSS RRGEDDSSTA LAVGGVSEET GWAEAWFNAI  300
PEEWGPGSPL WDDYHFPISN HKDDLDATQN SSSDTI
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A2e-20185243160ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
3gcc_A3e-20185243463ATERF1
2gcc_A3e-20185243463ATERF1
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.272160.0root
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306811850.0
Genevisible265418_at0.0
Expression AtlasAT2G20880-
AtGenExpressAT2G20880-
ATTED-IIAT2G20880-
Functional Description ? help Back to Top
Source Description
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. RGLG2 negatively regulates the drought stress response by mediating AtERF53 transcriptional activity in Arabidopsis.
    [PMID: 22095047]
  2. Data indicate that expression of AtERF53 in wild-type Arabidopsis was responsive to heat and abscisic acid (ABA) treatment.
    [PMID: 23625358]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT2G20880.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT2G20880
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0062340.0AC006234.4 Arabidopsis thaliana chromosome 2 clone F5H14 map mi148, complete sequence.
GenBankCP0026850.0CP002685.1 Arabidopsis thaliana chromosome 2, complete sequence.
GenBankAY0816590.0AY081659.1 Arabidopsis thaliana AP2 domain transcription factor (At2g20880) mRNA, complete cds.
GenBankAY0628430.0AY062843.1 Arabidopsis thaliana AP2 domain transcription factor (At2g20880; F5H14.15) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_179685.10.0ethylene-responsive transcription factor ERF053
SwissprotQ9SKT10.0ERF53_ARATH; Ethylene-responsive transcription factor ERF053
TrEMBLD7L5C00.0D7L5C0_ARALL; Putative uncharacterized protein
STRINGAT2G20880.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP6161718
MalvidsOGEM21412775
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  3. Koroleva OA,Tomlinson ML,Leader D,Shaw P,Doonan JH
    High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions.
    Plant J., 2005. 41(1): p. 162-74
    [PMID:15610358]
  4. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  5. Ditt RF, et al.
    The Arabidopsis thaliana transcriptome in response to Agrobacterium tumefaciens.
    Mol. Plant Microbe Interact., 2006. 19(6): p. 665-81
    [PMID:16776300]
  6. Osuna D, et al.
    Temporal responses of transcripts, enzyme activities and metabolites after adding sucrose to carbon-deprived Arabidopsis seedlings.
    Plant J., 2007. 49(3): p. 463-91
    [PMID:17217462]
  7. Ehlting J, et al.
    Comparative transcriptome analysis of Arabidopsis thaliana infested by diamond back moth (Plutella xylostella) larvae reveals signatures of stress response, secondary metabolism, and signalling.
    BMC Genomics, 2008. 9: p. 154
    [PMID:18400103]
  8. Endo A, et al.
    Drought induction of Arabidopsis 9-cis-epoxycarotenoid dioxygenase occurs in vascular parenchyma cells.
    Plant Physiol., 2008. 147(4): p. 1984-93
    [PMID:18550687]
  9. Cheng MC,Hsieh EJ,Chen JH,Chen HY,Lin TP
    Arabidopsis RGLG2, functioning as a RING E3 ligase, interacts with AtERF53 and negatively regulates the plant drought stress response.
    Plant Physiol., 2012. 158(1): p. 363-75
    [PMID:22095047]
  10. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  11. Hsieh EJ,Cheng MC,Lin TP
    Functional characterization of an abiotic stress-inducible transcription factor AtERF53 in Arabidopsis thaliana.
    Plant Mol. Biol., 2013. 82(3): p. 223-37
    [PMID:23625358]