PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G75540.1
Common NameAtBBX21, BBX21, F10A5.24, LHUS, STH2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family DBB
Protein Properties Length: 331aa    MW: 36633.6 Da    PI: 6.9099
Description salt tolerance homolog2
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G75540.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-B_box24.65.3e-08334435
     zf-B_box  4 rkCpeHeekelqlfCedCqqllCedClleeHk 35
                  +C+ ++++e++ fC+ ++  lC  C  + H+
  AT1G75540.1  3 IRCDVCDKEEASVFCTADEASLCGGCDHQVHH 34
                 58***************************974 PP

2zf-B_box30.86e-105794338
     zf-B_box  3 erkCpeHeekelqlfCedCqqllCedClleeHkg..Ht 38
                  + C+ +++k++ lfC++++  lC+dC +++H    Ht
  AT1G75540.1 57 SPLCDICQDKKALLFCQQDRAILCKDCDSSIHAAneHT 94
                 579*****************************556776 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5011910.651147IPR000315B-box-type zinc finger
PfamPF006436.5E-6334IPR000315B-box-type zinc finger
CDDcd000211.32E-6347No hitNo description
SMARTSM003361.5E-6447IPR000315B-box-type zinc finger
SuperFamilySSF578457.78E-55093No hitNo description
SMARTSM003368.4E-1555102IPR000315B-box-type zinc finger
PROSITE profilePS5011910.42455102IPR000315B-box-type zinc finger
PfamPF006433.3E-85795IPR000315B-box-type zinc finger
CDDcd000213.01E-1158102No hitNo description
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009640Biological Processphotomorphogenesis
GO:0009641Biological Processshade avoidance
GO:0005634Cellular Componentnucleus
GO:0000989Molecular Functiontranscription factor activity, transcription factor binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0008270Molecular Functionzinc ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009030anatomycarpel
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 331 aa     Download sequence    Send to blast
MKIRCDVCDK EEASVFCTAD EASLCGGCDH QVHHANKLAS KHLRFSLLYP SSSNTSSPLC  60
DICQDKKALL FCQQDRAILC KDCDSSIHAA NEHTKKHDRF LLTGVKLSAT SSVYKPTSKS  120
SSSSSSNQDF SVPGSSISNP PPLKKPLSAP PQSNKIQPFS KINGGDASVN QWGSTSTISE  180
YLMDTLPGWH VEDFLDSSLP TYGFSKSGDD DGVLPYMEPE DDNNTKRNNN NNNNNNNNTV  240
SLPSKNLGIW VPQIPQTLPS SYPNQYFSQD NNIQFGMYNK ETSPEVVSFA PIQNMKQQGQ  300
NNKRWYDDGG FTVPQITPPP LSSNKKFRSF W
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.347610.0leaf| root
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1864956290.0
Genevisible262975_at0.0
Expression AtlasAT1G75540-
AtGenExpressAT1G75540-
ATTED-IIAT1G75540-
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that acts as positive regulator of seedling photomorphogenesis (PubMed:17965270). Acts downstream of COP1 and play an important role in early and long-term adjustment of the shade avoidance syndrome (SAS) responses in natural environments (PubMed:21070414). {ECO:0000269|PubMed:17965270, ECO:0000269|PubMed:21070414}.
Function -- GeneRIF ? help Back to Top
  1. study identified STH2 (SALT TOLERANCE HOMOLOG2), a B-box protein in Arabidopsis thaliana, as a positive regulator of photomorphogenesis and report that the B-box domain plays a direct role in activating transcription in plants
    [PMID: 17965270]
  2. acts downstream of COP1 in the shade-avoidance syndrome
    [PMID: 21070414]
  3. BBX32 interacts with SALT TOLERANCE HOMOLOG2/BBX21, another B-box protein previously shown to interact with HY5.
    [PMID: 21632973]
  4. our study indicates that BBX21 coordinates with HY5 and ABI5 on the ABI5 promoter and that these transcriptional regulators work in concert to integrate light and ABA signaling in Arabidopsis thaliana.
    [PMID: 24586210]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G75540.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9LQZ7
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Enhanced number of emerged lateral roots. {ECO:0000269|PubMed:17965270}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G75540
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB4935360.0AB493536.1 Arabidopsis thaliana At1g75540 mRNA for hypothetical protein, partial cds, clone: RAAt1g75540.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_177686.10.0B-box zinc finger transcription factor BBX21
SwissprotQ9LQZ70.0BBX21_ARATH; B-box zinc finger protein 21
TrEMBLD7KSQ70.0D7KSQ7_ARALL; Zinc finger (B-box type) family protein
STRINGAT1G75540.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP29841130
MalvidsOGEM54002748
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Jiao Y, et al.
    A genome-wide analysis of blue-light regulation of Arabidopsis transcription factor gene expression during seedling development.
    Plant Physiol., 2003. 133(4): p. 1480-93
    [PMID:14605227]
  3. Datta S,Hettiarachchi C,Johansson H,Holm M
    SALT TOLERANCE HOMOLOG2, a B-box protein in Arabidopsis that activates transcription and positively regulates light-mediated development.
    Plant Cell, 2007. 19(10): p. 3242-55
    [PMID:17965270]
  4. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  5. Datta S, et al.
    LZF1/SALT TOLERANCE HOMOLOG3, an Arabidopsis B-box protein involved in light-dependent development and gene expression, undergoes COP1-mediated ubiquitination.
    Plant Cell, 2008. 20(9): p. 2324-38
    [PMID:18796637]
  6. Datta S,Johansson H,Hettiarachchi C,Holm M
    STH2 has 2 B there: An insight into the role of B-box containing proteins in Arabidopsis.
    Plant Signal Behav, 2008. 3(8): p. 547-8
    [PMID:19704462]
  7. Khanna R, et al.
    The Arabidopsis B-box zinc finger family.
    Plant Cell, 2009. 21(11): p. 3416-20
    [PMID:19920209]
  8. Crocco CD,Holm M,Yanovsky MJ,Botto JF
    AtBBX21 and COP1 genetically interact in the regulation of shade avoidance.
    Plant J., 2010. 64(4): p. 551-62
    [PMID:21070414]
  9. Crocco CD,Holm M,Yanovsky MJ,Botto JF
    Function of B-BOX under shade.
    Plant Signal Behav, 2011. 6(1): p. 101-4
    [PMID:21301219]
  10. Holtan HE, et al.
    BBX32, an Arabidopsis B-Box protein, functions in light signaling by suppressing HY5-regulated gene expression and interacting with STH2/BBX21.
    Plant Physiol., 2011. 156(4): p. 2109-23
    [PMID:21632973]
  11. Song YH,Lee I,Lee SY,Imaizumi T,Hong JC
    CONSTANS and ASYMMETRIC LEAVES 1 complex is involved in the induction of FLOWERING LOCUS T in photoperiodic flowering in Arabidopsis.
    Plant J., 2012. 69(2): p. 332-42
    [PMID:21950734]
  12. Yamawaki S,Yamashino T,Nakamichi N,Nakanishi H,Mizuno T
    Light-responsive double B-box containing transcription factors are conserved in Physcomitrella patens.
    Biosci. Biotechnol. Biochem., 2011. 75(10): p. 2037-41
    [PMID:21979077]
  13. Sarmiento F
    The BBX subfamily IV: additional cogs and sprockets to fine-tune light-dependent development.
    Plant Signal Behav, 2013. 8(4): p. e23831
    [PMID:23425851]
  14. Xu D, et al.
    Convergence of Light and ABA signaling on the ABI5 promoter.
    PLoS Genet., 2014. 10(2): p. e1004197
    [PMID:24586210]
  15. K MJ,Laxmi A
    DUF581 is plant specific FCS-like zinc finger involved in protein-protein interaction.
    PLoS ONE, 2014. 9(6): p. e99074
    [PMID:24901469]