PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G74930.1
Common NameERF018, F25A4.10, F9E10.22, ORA47
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 195aa    MW: 21898.4 Da    PI: 4.5027
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G74930.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP259.67.4e-191969155
          AP2  1 sgykGVrwdkkrgrWvAeIrdpsengkr..krfslgkfgtaeeAakaaiaarkkleg 55
                 s+ykGVr +k +g+Wv+eIr p     +   r++lg+++t+e+Aa+a +aa  +l+g
  AT1G74930.1 19 SKYKGVRKRK-WGKWVSEIRLP-----HsrERIWLGSYDTPEKAARAFDAAQFCLRG 69
                 89*****999.**********7.....335*************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541714.71E-211978IPR016177DNA-binding domain
CDDcd000182.17E-291979No hitNo description
PfamPF008477.4E-121969IPR001471AP2/ERF domain
SMARTSM003804.8E-322083IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.109.0E-292078IPR001471AP2/ERF domain
PROSITE profilePS5103222.0892077IPR001471AP2/ERF domain
PRINTSPR003671.2E-92132IPR001471AP2/ERF domain
PRINTSPR003671.2E-94359IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001944Biological Processvasculature development
GO:0002213Biological Processdefense response to insect
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009611Biological Processresponse to wounding
GO:0009873Biological Processethylene-activated signaling pathway
GO:0051301Biological Processcell division
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009009anatomyplant embryo
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 195 aa     Download sequence    Send to blast
MVKQAMKEEE KKRNTAMQSK YKGVRKRKWG KWVSEIRLPH SRERIWLGSY DTPEKAARAF  60
DAAQFCLRGG DANFNFPNNP PSISVEKSLT PPEIQEAAAR FANTFQDIVK GEEESGLVPG  120
SEIRPESPST SASVATSTVD YDFSFLDLLP MNFGFDSFSD DFSGFSGGDR FTEILPIEDY  180
GGESLLDESL ILWDF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A2e-1516781073Ethylene-responsive transcription factor ERF096
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
11027KKRNTAMQSKYKGVRKRK
22127KGVRKRK
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.348250.0bud| leaf| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306990580.0
Genevisible262211_at0.0
Expression AtlasAT1G74930-
AtGenExpressAT1G74930-
ATTED-IIAT1G74930-
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the DREB subfamily A-5 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 15 members in this subfamily including RAP2.1, RAP2.9 and RAP2.10.
UniProtProbably acts as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250}.
Function -- GeneRIF ? help Back to Top
  1. ORA47 is proposed to play a role in the biosynthesis of jasmonic acid and abscissic acid and in regulating the biosynthesis and/or signaling of a suite of phytohormone genes when plants are subjected to wounding and water stress.
    [PMID: 26974851]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00601PBM24477691Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G74930.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G17420(A)
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G74930
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0132580.0AC013258.5 Arabidopsis thaliana chromosome 1 BAC F9E10 genomic sequence, complete sequence.
GenBankAY1283090.0AY128309.1 Arabidopsis thaliana AP2 domain containing protein, putative (At1g74930) mRNA, complete cds.
GenBankBT0033480.0BT003348.1 Arabidopsis thaliana AP2 domain containing protein, putative (At1g74930) mRNA, complete cds.
GenBankCP0026840.0CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
GenBankF25A40.0AC008263.2 Arabidopsis thaliana chromosome 1 BAC F25A4 sequence, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_177631.11e-142Integrase-type DNA-binding superfamily protein
SwissprotQ9S7L51e-143ERF18_ARATH; Ethylene-responsive transcription factor ERF018
TrEMBLA0A178W2601e-141A0A178W260_ARATH; ORA47
STRINGAT1G74930.11e-142(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM16142890
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  3. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  4. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  5. Ma S,Gong Q,Bohnert HJ
    Dissecting salt stress pathways.
    J. Exp. Bot., 2006. 57(5): p. 1097-107
    [PMID:16510518]
  6. Walley JW, et al.
    Mechanical stress induces biotic and abiotic stress responses via a novel cis-element.
    PLoS Genet., 2007. 3(10): p. 1800-12
    [PMID:17953483]
  7. Pauwels L, et al.
    Mapping methyl jasmonate-mediated transcriptional reprogramming of metabolism and cell cycle progression in cultured Arabidopsis cells.
    Proc. Natl. Acad. Sci. U.S.A., 2008. 105(4): p. 1380-5
    [PMID:18216250]
  8. Cartagena JA, et al.
    The Arabidopsis SDG4 contributes to the regulation of pollen tube growth by methylation of histone H3 lysines 4 and 36 in mature pollen.
    Dev. Biol., 2008. 315(2): p. 355-68
    [PMID:18252252]
  9. Ferreira FJ,Guo C,Coleman JR
    Reduction of plastid-localized carbonic anhydrase activity results in reduced Arabidopsis seedling survivorship.
    Plant Physiol., 2008. 147(2): p. 585-94
    [PMID:18434607]
  10. Ascencio-Ib
    Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.
    Plant Physiol., 2008. 148(1): p. 436-54
    [PMID:18650403]
  11. Pauwels L,Goossens A
    Fine-tuning of early events in the jasmonate response.
    Plant Signal Behav, 2008. 3(10): p. 846-7
    [PMID:20140232]
  12. Kerchev PI, et al.
    The transcription factor ABI4 Is required for the ascorbic acid-dependent regulation of growth and regulation of jasmonate-dependent defense signaling pathways in Arabidopsis.
    Plant Cell, 2011. 23(9): p. 3319-34
    [PMID:21926335]
  13. Etchells JP,Provost CM,Turner SR
    Plant vascular cell division is maintained by an interaction between PXY and ethylene signalling.
    PLoS Genet., 2012. 8(11): p. e1002997
    [PMID:23166504]
  14. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  15. Lumba S, et al.
    A mesoscale abscisic acid hormone interactome reveals a dynamic signaling landscape in Arabidopsis.
    Dev. Cell, 2014. 29(3): p. 360-72
    [PMID:24823379]
  16. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  17. Chen HY, et al.
    ORA47 (octadecanoid-responsive AP2/ERF-domain transcription factor 47) regulates jasmonic acid and abscisic acid biosynthesis and signaling through binding to a novel cis-element.
    New Phytol., 2016. 211(2): p. 599-613
    [PMID:26974851]
  18. Hickman R, et al.
    Architecture and Dynamics of the Jasmonic Acid Gene Regulatory Network.
    Plant Cell, 2017. 29(9): p. 2086-2105
    [PMID:28827376]