PlantTFDB
Plant Transcription Factor Database
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G69010.1
Common NameBHLH102, BIM2, EN125, T6L1.19
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 311aa    MW: 34486.9 Da    PI: 5.0332
Description BES1-interacting Myc-like protein 2
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G69010.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH48.12.1e-154796255
                 HHHHHHHHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHHH CS
          HLH  2 rrahnerErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksLq 55
                 r +h+  E+rRR++iN++f+ Lrel+P++     +K + a+ L ++++Y+++Lq
  AT1G69010.1 47 RSKHSVTEQRRRSKINERFQILRELIPNS----EQKRDTASFLLEVIDYVQYLQ 96
                 899*************************8....79******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF474592.22E-1843116IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.104.4E-2244118IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088816.3554595IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.24E-1447100No hitNo description
PfamPF000109.1E-134796IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.2E-1151101IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006351Biological Processtranscription, DNA-templated
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 311 aa     Download sequence    Send to blast
MRTGKGNQEE EDYGEEDFNS KREGPSSNTT VHSNRDSKEN DKASAIRSKH SVTEQRRRSK  60
INERFQILRE LIPNSEQKRD TASFLLEVID YVQYLQEKVQ KYEGSYPGWS QEPTKLTPWR  120
NNHWRVQSLG NHPVAINNGS GPGIPFPGKF EDNTVTSTPA IIAEPQIPIE SDKARAITGI  180
SIESQPELDD KGLPPLQPIL PMVQGEQANE CPATSDGLGQ SNDLVIEGGT ISISSAYSHE  240
LLSSLTQALQ NAGIDLSQAK LSVQIDLGKR ANQGLTHEEP SSKNPLSYDT QGRDSSVEEE  300
SEHSHKRMKT L
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.354580.0flower| leaf| root
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1453373070.0
Genevisible259645_at0.0
Expression AtlasAT1G69010-
AtGenExpressAT1G69010-
ATTED-IIAT1G69010-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed constitutively in roots, leaves, stems, and flowers. {ECO:0000269|PubMed:12679534}.
Functional Description ? help Back to Top
Source Description
UniProtPositive brassinosteroid-signaling protein.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00219DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G69010.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by heat treatment. {ECO:0000269|PubMed:12679534}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT2G20180 (A)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDbrassinosteroid
Interaction ? help Back to Top
Source Intact With
BioGRIDAT1G69010
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G69010
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0023520.0BT002352.1 Arabidopsis thaliana clone C104950 putative DNA-binding protein (At1g69010) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_177064.10.0BES1-interacting Myc-like protein 2
SwissprotQ9CAA40.0BIM2_ARATH; Transcription factor BIM2
TrEMBLA0A178WF300.0A0A178WF30_ARATH; BIM2
STRINGAT1G69010.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM59872745
Representative plantOGRP13601747
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Zhao L, et al.
    Overexpression of LSH1, a member of an uncharacterised gene family, causes enhanced light regulation of seedling development.
    Plant J., 2004. 37(5): p. 694-706
    [PMID:14871309]
  7. Hu W,Wang Y,Bowers C,Ma H
    Isolation, sequence analysis, and expression studies of florally expressed cDNAs in Arabidopsis.
    Plant Mol. Biol., 2003. 53(4): p. 545-63
    [PMID:15010618]
  8. Yin Y, et al.
    A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis.
    Cell, 2005. 120(2): p. 249-59
    [PMID:15680330]
  9. Sottosanto JB,Saranga Y,Blumwald E
    Impact of AtNHX1, a vacuolar Na+/H+ antiporter, upon gene expression during short- and long-term salt stress in Arabidopsis thaliana.
    BMC Plant Biol., 2007. 7: p. 18
    [PMID:17411438]
  10. Oh E, et al.
    Genome-wide analysis of genes targeted by PHYTOCHROME INTERACTING FACTOR 3-LIKE5 during seed germination in Arabidopsis.
    Plant Cell, 2009. 21(2): p. 403-19
    [PMID:19244139]
  11. Skinner MK,Rawls A,Wilson-Rawls J,Roalson EH
    Basic helix-loop-helix transcription factor gene family phylogenetics and nomenclature.
    Differentiation, 2010. 80(1): p. 1-8
    [PMID:20219281]
  12. Arabidopsis Interactome Mapping Consortium
    Evidence for network evolution in an Arabidopsis interactome map.
    Science, 2011. 333(6042): p. 601-7
    [PMID:21798944]
  13. Cifuentes-Esquivel N, et al.
    The bHLH proteins BEE and BIM positively modulate the shade avoidance syndrome in Arabidopsis seedlings.
    Plant J., 2013. 75(6): p. 989-1002
    [PMID:23763263]
  14. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]