PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G68640.1
Common NameF24J5.12, PAN, TGA8
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bZIP
Protein Properties Length: 452aa    MW: 50457.5 Da    PI: 6.2365
Description bZIP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G68640.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1bZIP_1322.6e-10166206542
                  CHHHCHHHHHHHHHHHHHHHHHHHHHHHH...HHHHHHHHH CS
       bZIP_1   5 krerrkqkNReAArrsRqRKkaeieeLee...kvkeLeaeN 42 
                  +  rr+++NReAAr+sR+RKka++++Le+   + ++Le+e 
  AT1G68640.1 166 RTLRRLAQNREAARKSRLRKKAYVQQLENsriRLAQLEEEL 206
                  456999*********************98333455555554 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.20.5.1708.5E-8158211No hitNo description
SMARTSM003387.1E-7162233IPR004827Basic-leucine zipper domain
PROSITE profilePS502179.404164208IPR004827Basic-leucine zipper domain
PfamPF001705.2E-7166206IPR004827Basic-leucine zipper domain
CDDcd147089.23E-21166214No hitNo description
SuperFamilySSF579592.17E-6166209No hitNo description
PROSITE patternPS000360169184IPR004827Basic-leucine zipper domain
PfamPF141441.3E-27251324IPR025422Transcription factor TGA like domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009909Biological Processregulation of flower development
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0005515Molecular Functionprotein binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0006081anatomyprimary root apical meristem
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009031anatomysepal
PO:0009046anatomyflower
PO:0009049anatomyinflorescence
PO:0020003anatomyplant ovule
PO:0020130anatomycentral root cap
PO:0020149anatomyquiescent center
PO:0025022anatomycollective leaf structure
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007611developmental stagepetal differentiation and expansion stage
Sequence ? help Back to Top
Protein Sequence    Length: 452 aa     Download sequence    Send to blast
MQSSFKTVPF TPDFYSQSSY FFRGDSCLEE FHQPVNGFHH EEAIDLSPNV TIASANLHYT  60
TFDTVMDCGG GGGGGLRERL EGGEEECLDT GQLVYQKGTR LVGGGVGEVN SSWCDSVSAM  120
ADNSQHTDTS TDIDTDDKTQ LNGGHQGMLL ATNCSDQSNV KSSDQRTLRR LAQNREAARK  180
SRLRKKAYVQ QLENSRIRLA QLEEELKRAR QQGSLVERGV SADHTHLAAG NGVFSFELEY  240
TRWKEEHQRM INDLRSGVNS QLGDNDLRVL VDAVMSHYDE IFRLKGIGTK VDVFHMLSGM  300
WKTPAERFFM WLGGFRSSEL LKILGNHVDP LTDQQLIGIC NLQQSSQQAE DALSQGMEAL  360
QQSLLETLSS ASMGPNSSAN VADYMGHMAM AMGKLGTLEN FLRQADLLRQ QTLQQLHRIL  420
TTRQAARAFL VIHDYISRLR ALSSLWLARP RD
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO425630540.0
Genevisible262278_at0.0
Expression AtlasAT1G68640-
AtGenExpressAT1G68640-
ATTED-IIAT1G68640-
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Expressed in the apical meristem, the floral meristem, each whorl of organ primordia, and in ovule primordia during wild-type flower development. {ECO:0000269|PubMed:9990857}.
Functional Description ? help Back to Top
Source Description
TAIREncodes bZIP-transcription factor. Mutant plants have extra floral organs. PAN is essential for AG activation in early flowers of short-day-grown plants.
UniProtTranscriptional activator involved in the determination of floral organ number. Acts to determine floral organ patterning by establishing floral organ primordia in specific numbers and positions. Plays a role in regulating stem cell fate by directly controlling AG expression. Binds to the 5'-AAGAAT-3' cis-acting element found in AG promoter. Might represent a target for a post-translational modification by GRXC7/ROXY1. {ECO:0000269|PubMed:19395638, ECO:0000269|PubMed:19395639, ECO:0000269|PubMed:9990857}.
Function -- GeneRIF ? help Back to Top
  1. PERIANTHIA (PAN) plays a role in regulating stem cell fate by directly controlling AG expression and suggest that this activity is spatially restricted to the centermost region of the AG expression domain.
    [PMID: 19395638]
  2. PAN and AG are engaged in a negative-feedback loop, which might be mediated by the stem-cell-inducing transcription factor WUSCHEL (WUS).
    [PMID: 19395639]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G68640.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT4G18960 (R)
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT2G17950(R), AT4G18960(A)
Interaction ? help Back to Top
Source Intact With
IntActSearch Q9SX27
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Mutant plants have extra floral organs. The modal numbers of organs in mutant flowers are 5 sepals, 5 petals, 5 stamens, and 2 carpels in contrast with the tetramerous pattern of the wild type. {ECO:0000269|PubMed:8620853, ECO:0000269|PubMed:9990857}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G68640
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0085860.0BT008586.1 Arabidopsis thaliana clone U50929 putative bZIP transcription factor, PERIANTHIA (At1g68640) mRNA, complete cds.
GenBankAK1182860.0AK118286.1 Arabidopsis thaliana At1g68640 mRNA for putative bZip transcription factor PERIANTHIA (PAN) / AtbZip46, complete cds, clone: RAFL19-57-M21.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_177031.10.0transcription factor PERIANTHIA
SwissprotQ9SX270.0PAN_ARATH; Transcription factor PERIANTHIA
TrEMBLD7KWE60.0D7KWE6_ARALL; Transcription factor perianthia
STRINGAT1G68640.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP7221667
MalvidsOGEM66728133
Publications ? help Back to Top
  1. Meyerowitz EM,Running MP,Sakai H,Williams RW
    Multiple modes of cell division control in Arabidopsis flower development.
    Symp. Soc. Exp. Biol., 1998. 51: p. 19-26
    [PMID:10645419]
  2. Chuang CF,Meyerowitz EM
    Specific and heritable genetic interference by double-stranded RNA in Arabidopsis thaliana.
    Proc. Natl. Acad. Sci. U.S.A., 2000. 97(9): p. 4985-90
    [PMID:10781109]
  3. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  4. Fletcher JC
    The ULTRAPETALA gene controls shoot and floral meristem size in Arabidopsis.
    Development, 2001. 128(8): p. 1323-33
    [PMID:11262233]
  5. Jakoby M, et al.
    bZIP transcription factors in Arabidopsis.
    Trends Plant Sci., 2002. 7(3): p. 106-11
    [PMID:11906833]
  6. Seki M, et al.
    Functional annotation of a full-length Arabidopsis cDNA collection.
    Science, 2002. 296(5565): p. 141-5
    [PMID:11910074]
  7. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  8. Hepworth SR,Zhang Y,McKim S,Li X,Haughn GW
    BLADE-ON-PETIOLE-dependent signaling controls leaf and floral patterning in Arabidopsis.
    Plant Cell, 2005. 17(5): p. 1434-48
    [PMID:15805484]
  9. Nawy T, et al.
    Transcriptional profile of the Arabidopsis root quiescent center.
    Plant Cell, 2005. 17(7): p. 1908-25
    [PMID:15937229]
  10. Li S, et al.
    Nuclear activity of ROXY1, a glutaredoxin interacting with TGA factors, is required for petal development in Arabidopsis thaliana.
    Plant Cell, 2009. 21(2): p. 429-41
    [PMID:19218396]
  11. Skinner DJ,Gasser CS
    Expression-based discovery of candidate ovule development regulators through transcriptional profiling of ovule mutants.
    BMC Plant Biol., 2009. 9: p. 29
    [PMID:19291320]
  12. Das P, et al.
    Floral stem cell termination involves the direct regulation of AGAMOUS by PERIANTHIA.
    Development, 2009. 136(10): p. 1605-11
    [PMID:19395638]
  13. Maier AT, et al.
    Dual roles of the bZIP transcription factor PERIANTHIA in the control of floral architecture and homeotic gene expression.
    Development, 2009. 136(10): p. 1613-20
    [PMID:19395639]
  14. Krizek B
    AINTEGUMENTA and AINTEGUMENTA-LIKE6 act redundantly to regulate Arabidopsis floral growth and patterning.
    Plant Physiol., 2009. 150(4): p. 1916-29
    [PMID:19542297]
  15. Irish VF
    The flowering of Arabidopsis flower development.
    Plant J., 2010. 61(6): p. 1014-28
    [PMID:20409275]
  16. Xu M, et al.
    Arabidopsis BLADE-ON-PETIOLE1 and 2 promote floral meristem fate and determinacy in a previously undefined pathway targeting APETALA1 and AGAMOUS-LIKE24.
    Plant J., 2010. 63(6): p. 974-89
    [PMID:20626659]
  17. Li S,Gutsche N,Zachgo S
    The ROXY1 C-terminal L**LL motif is essential for the interaction with TGA transcription factors.
    Plant Physiol., 2011. 157(4): p. 2056-68
    [PMID:21960138]
  18. Zander M,Chen S,Imkampe J,Thurow C,Gatz C
    Repression of the Arabidopsis thaliana jasmonic acid/ethylene-induced defense pathway by TGA-interacting glutaredoxins depends on their C-terminal ALWL motif.
    Mol Plant, 2012. 5(4): p. 831-40
    [PMID:22207719]
  19. Z
    JAIBA, a class-II HD-ZIP transcription factor involved in the regulation of meristematic activity, and important for correct gynoecium and fruit development in Arabidopsis.
    Plant J., 2012. 71(2): p. 314-26
    [PMID:22409594]
  20. Canet JV,Dob
    The BLADE-ON-PETIOLE genes of Arabidopsis are essential for resistance induced by methyl jasmonate.
    BMC Plant Biol., 2012. 12: p. 199
    [PMID:23116333]
  21. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  22. Running MP,Meyerowitz EM
    Mutations in the PERIANTHIA gene of Arabidopsis specifically alter floral organ number and initiation pattern.
    Development, 1996. 122(4): p. 1261-9
    [PMID:8620853]
  23. Roe JL,Nemhauser JL,Zambryski PC
    TOUSLED participates in apical tissue formation during gynoecium development in Arabidopsis.
    Plant Cell, 1997. 9(3): p. 335-53
    [PMID:9090879]
  24. Sessions A, et al.
    ETTIN patterns the Arabidopsis floral meristem and reproductive organs.
    Development, 1997. 124(22): p. 4481-91
    [PMID:9409666]
  25. Chuang CF,Running MP,Williams RW,Meyerowitz EM
    The PERIANTHIA gene encodes a bZIP protein involved in the determination of floral organ number in Arabidopsis thaliana.
    Genes Dev., 1999. 13(3): p. 334-44
    [PMID:9990857]