PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G66810.1
Common NameF4N21.6
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C3H
Protein Properties Length: 310aa    MW: 35108.6 Da    PI: 7.3007
Description C3H family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G66810.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-CCCH406.4e-13234258226
                  -S---SGGGGTS--TTTTT-SS-SS CS
      zf-CCCH   2 ktelCrffartGtCkyGdrCkFaHg 26 
                  ktelC+ +++tG C yGd+C+FaHg
  AT1G66810.1 234 KTELCNKWQETGACCYGDNCQFAHG 258
                  9***********************8 PP

2zf-CCCH18.92.7e-06271296126
                  --S---SGGGGTS.--TTTTT-SS-SS CS
      zf-CCCH   1 yktelCrffartG.tCkyGdrCkFaHg 26 
                  ykte Cr  + tG  C+yG rC+F H+
  AT1G66810.1 271 YKTEVCR-MMVTGaMCPYGHRCHFRHS 296
                  9******.9***************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:4.10.1000.107.3E-18227265IPR000571Zinc finger, CCCH-type
SuperFamilySSF902298.9E-11230264IPR000571Zinc finger, CCCH-type
PROSITE profilePS5010315.3232260IPR000571Zinc finger, CCCH-type
SMARTSM003569.4E-6232259IPR000571Zinc finger, CCCH-type
PfamPF006424.2E-10234258IPR000571Zinc finger, CCCH-type
Gene3DG3DSA:4.10.1000.105.2E-12266299IPR000571Zinc finger, CCCH-type
SuperFamilySSF902297.72E-9266301IPR000571Zinc finger, CCCH-type
PROSITE profilePS5010313.188270298IPR000571Zinc finger, CCCH-type
SMARTSM003565.8E-4270297IPR000571Zinc finger, CCCH-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0051511Biological Processnegative regulation of unidimensional cell growth
GO:0061158Biological Process3'-UTR-mediated mRNA destabilization
GO:1901347Biological Processnegative regulation of secondary cell wall biogenesis
GO:0005829Cellular Componentcytosol
GO:0003677Molecular FunctionDNA binding
GO:0003729Molecular FunctionmRNA binding
GO:0003730Molecular FunctionmRNA 3'-UTR binding
GO:0046872Molecular Functionmetal ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 310 aa     Download sequence    Send to blast
MEKLAASTVT DLACVTAINS SPPPLSPISE QSFNNKHQEE FAASFASLYN SIFSPESLSP  60
SPPSSSSPPS RVDTTTEHRL LQAKLILEYD ELNEHYELCL NRLQSLMTEL DSLRHENDSL  120
RFENSDLLKL IRISTSSSSS VSPPAPIHNR QFRHQISDSR SAKRNNQERN SLPKSISVRS  180
QGYLKINHGF EASDLQTSQL SSNSVSSSQK VCVVQTKGER EALELEVYRQ GMMKTELCNK  240
WQETGACCYG DNCQFAHGID ELRPVIRHPR YKTEVCRMMV TGAMCPYGHR CHFRHSLTDQ  300
ERMMMMMLTR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1rgo_A7e-22234296567Butyrate response factor 2
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO1453372350.0
Genevisible256367_at0.0
Expression AtlasAT1G66810-
AtGenExpressAT1G66810-
ATTED-IIAT1G66810-
Function -- GeneRIF ? help Back to Top
  1. At1g66810 (AtC3H14) promotor has a cis-acting regulatory motif that is recognized by MYB46.
    [PMID: 22271306]
  2. At1g66810 plays a key role in both transcriptional and post-transcriptional regulation.At1g66810 is zinc-finger protein.At1g66810 binds to its target mRNAs in a sequence-specific manner and affects cell elongation.
    [PMID: 25228083]
  3. C3H14 and its homologue C3H15 redundantly regulate secondary wall formation and they additionally function in anther development.
    [PMID: 25732536]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G66810.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G66810
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0132880.0AC013288.7 Arabidopsis thaliana chromosome 1 BAC F4N21 genomic sequence, complete sequence.
GenBankCP0026840.0CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_176853.10.0zinc finger CCCH domain-containing protein
SwissprotQ9C9N30.0C3H14_ARATH; Zinc finger CCCH domain-containing protein 14
TrEMBLD7KUE41e-163D7KUE4_ARALL; Putative uncharacterized protein
STRINGAT1G66810.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM106232533
Representative plantOGRP20581636
Publications ? help Back to Top
  1. Dal Bosco C, et al.
    Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.
    J. Biol. Chem., 2004. 279(2): p. 1060-9
    [PMID:14576160]
  2. Delaney KJ, et al.
    Calmodulin interacts with and regulates the RNA-binding activity of an Arabidopsis polyadenylation factor subunit.
    Plant Physiol., 2006. 140(4): p. 1507-21
    [PMID:16500995]
  3. Culligan KM,Robertson CE,Foreman J,Doerner P,Britt AB
    ATR and ATM play both distinct and additive roles in response to ionizing radiation.
    Plant J., 2006. 48(6): p. 947-61
    [PMID:17227549]
  4. Wang D, et al.
    Genome-wide analysis of CCCH zinc finger family in Arabidopsis and rice.
    BMC Genomics, 2008. 9: p. 44
    [PMID:18221561]
  5. Hanada K, et al.
    Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.
    Mol. Biol. Evol., 2011. 28(1): p. 377-82
    [PMID:20736450]
  6. Kim WC,Ko JH,Han KH
    Identification of a cis-acting regulatory motif recognized by MYB46, a master transcriptional regulator of secondary wall biosynthesis.
    Plant Mol. Biol., 2012. 78(4-5): p. 489-501
    [PMID:22271306]
  7. Kim WC, et al.
    AtC3H14, a plant-specific tandem CCCH zinc-finger protein, binds to its target mRNAs in a sequence-specific manner and affects cell elongation in Arabidopsis thaliana.
    Plant J., 2014. 80(5): p. 772-84
    [PMID:25228083]
  8. Chai G, et al.
    Arabidopsis C3H14 and C3H15 have overlapping roles in the regulation of secondary wall thickening and anther development.
    J. Exp. Bot., 2015. 66(9): p. 2595-609
    [PMID:25732536]