PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G46264.1
Common NameAT-HSFB4, F2G19.8, HSF02, HSFB4, SCZ
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family HSF
Protein Properties Length: 348aa    MW: 39615.4 Da    PI: 7.8846
Description heat shock transcription factor B4
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G46264.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HSF_DNA-bind114.38e-36351272103
                   HHHHHHHHHCTGGGTTTSEESSSSSEEEES-HHHHHHHTHHHHSTT--HHHHHHHHHHTTEEE---SSBTTTTXTTSEEEEESXXXXXXXXXXXXXX CS
  HSF_DNA-bind   2 FlkklyeiledeelkeliswsengnsfvvldeeefakkvLpkyFkhsnfaSFvRQLnmYgFkkvkdeekkskskekiweFkhksFkkgkkellekik 98 
                   Fl+k+y++++d+++++++sw ++ ++fvv+ + efa+++Lp+yFkh+nf+SFvRQLn+YgF+k+  ++         weF+++ Fk+g+k+ll++i+
   AT1G46264.1  35 FLTKTYQLVDDPATDHVVSWGDDDTTFVVWRPPEFARDLLPNYFKHNNFSSFVRQLNTYGFRKIVPDR---------WEFANEFFKRGEKHLLCEIH 122
                   9*****************************************************************99.........******************** PP

                   XXXXX CS
  HSF_DNA-bind  99 rkkse 103
                   r+k++
   AT1G46264.1 123 RRKTS 127
                   **987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:1.10.10.106.1E-3827119IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM004158.1E-6131124IPR000232Heat shock factor (HSF)-type, DNA-binding
SuperFamilySSF467858.71E-3532124IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF004478.1E-3235124IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.1E-193558IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.1E-197385IPR000232Heat shock factor (HSF)-type, DNA-binding
PROSITE patternPS0043407498IPR000232Heat shock factor (HSF)-type, DNA-binding
PRINTSPR000561.1E-198698IPR000232Heat shock factor (HSF)-type, DNA-binding
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0008356Biological Processasymmetric cell division
GO:0005634Cellular Componentnucleus
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0042802Molecular Functionidentical protein binding
GO:0043565Molecular Functionsequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000013anatomycauline leaf
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009052anatomyflower pedicel
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 348 aa     Download sequence    Send to blast
MAMMVENSYG GYGGGGGERI QLMVEGQGKA VPAPFLTKTY QLVDDPATDH VVSWGDDDTT  60
FVVWRPPEFA RDLLPNYFKH NNFSSFVRQL NTYGFRKIVP DRWEFANEFF KRGEKHLLCE  120
IHRRKTSQMI PQQHSPFMSH HHAPPQIPFS GGSFFPLPPP RVTTPEEDHY WCDDSPPSRP  180
RVIPQQIDTA AQVTALSEDN ERLRRSNTVL MSELAHMKKL YNDIIYFVQN HVKPVAPSNN  240
SSYLSSFLQK QQQQQPPTLD YYNTATVNAT NLNALNSSPP TSQSSITVLE DDHTNHHDQS  300
NMRKTKLFGV SLPSSKKRSH HFSDQTSKTR LVLDQSDLAL NLMTASTR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ldu_A2e-223112717123Heat shock factor protein 1
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1315319KKRSH
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.499540.0flower
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible245800_at0.0
Expression AtlasAT1G46264-
AtGenExpressAT1G46264-
ATTED-IIAT1G46264-
Functional Description ? help Back to Top
Source Description
TAIREncodes SCHIZORIZA, a member of Heat Shock Transcription Factor (Hsf) family. Functions as a nuclear factor regulating asymmetry of stem cell divisions.
UniProtTranscriptional regulator that specifically binds DNA sequence 5'-AGAAnnTTCT-3' known as heat shock promoter elements (HSE).
Function -- GeneRIF ? help Back to Top
  1. SCHIZORIZA (SCZ) necessary for the early establishment of the stem cells that produce the ground tissue in embryonic root meristem. [SCHIZORIZA]
    [PMID: 20417101]
  2. The mutant phenotypes of Hsf-OE plants are without precedence and indicate that class B-Hsfs may play an important role in root development.
    [PMID: 22677791]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00187DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G46264.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G46264
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB4934990.0AB493499.1 Arabidopsis thaliana At1g46264 mRNA for hypothetical protein, partial cds, clone: RAAt1g46264.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_175142.10.0heat shock transcription factor B4
SwissprotQ9C6350.0HSFB4_ARATH; Heat stress transcription factor B-4
TrEMBLC0SUZ60.0C0SUZ6_ARATH; Uncharacterized protein At1g46264 (Fragment)
STRINGAT1G46264.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM29002866
Representative plantOGRP9617233
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Nover L, et al.
    Arabidopsis and the heat stress transcription factor world: how many heat stress transcription factors do we need?
    Cell Stress Chaperones, 2001. 6(3): p. 177-89
    [PMID:11599559]
  3. Castelli V, et al.
    Whole genome sequence comparisons and "full-length" cDNA sequences: a combined approach to evaluate and improve Arabidopsis genome annotation.
    Genome Res., 2004. 14(3): p. 406-13
    [PMID:14993207]
  4. Pischke MS,Huttlin EL,Hegeman AD,Sussman MR
    A transcriptome-based characterization of habituation in plant tissue culture.
    Plant Physiol., 2006. 140(4): p. 1255-78
    [PMID:16489130]
  5. Guo J, et al.
    Genome-wide analysis of heat shock transcription factor families in rice and Arabidopsis.
    J Genet Genomics, 2008. 35(2): p. 105-18
    [PMID:18407058]
  6. Ikeda M,Ohme-Takagi M
    A novel group of transcriptional repressors in Arabidopsis.
    Plant Cell Physiol., 2009. 50(5): p. 970-5
    [PMID:19324928]
  7. ten Hove CA, et al.
    SCHIZORIZA encodes a nuclear factor regulating asymmetry of stem cell divisions in the Arabidopsis root.
    Curr. Biol., 2010. 20(5): p. 452-7
    [PMID:20171102]
  8. Pernas M,Ryan E,Dolan L
    SCHIZORIZA controls tissue system complexity in plants.
    Curr. Biol., 2010. 20(9): p. 818-23
    [PMID:20417101]
  9. Zhu X,Thalor SK,Takahashi Y,Berberich T,Kusano T
    An inhibitory effect of the sequence-conserved upstream open-reading frame on the translation of the main open-reading frame of HsfB1 transcripts in Arabidopsis.
    Plant Cell Environ., 2012. 35(11): p. 2014-30
    [PMID:22571635]
  10. Begum T,Reuter R,Sch
    Overexpression of AtHsfB4 induces specific effects on root development of Arabidopsis.
    Mech. Dev., 2013. 130(1): p. 54-60
    [PMID:22677791]