PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G34790.1
Common NameF11O6.15, TT1, WIP1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family C2H2
Protein Properties Length: 303aa    MW: 34511.9 Da    PI: 7.5482
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G34790.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H217.98.6e-06145164120
                  EEETTTTEEESSHHHHHHHH CS
      zf-C2H2   1 ykCpdCgksFsrksnLkrHi 20 
                  ++C+ C k+F+r  nL+ H+
  AT1G34790.1 145 FSCHVCFKTFNRYNNLQMHM 164
                  89*****************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576673.19E-5127167No hitNo description
PROSITE profilePS5015710.055145172IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.603.5E-4145164IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280147167IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009813Biological Processflavonoid biosynthetic process
GO:0005634Cellular Componentnucleus
GO:0003676Molecular Functionnucleic acid binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046872Molecular Functionmetal ion binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0009010anatomyseed
Sequence ? help Back to Top
Protein Sequence    Length: 303 aa     Download sequence    Send to blast
MESPPLYEIS SSSSSEKPRH HFQSLDLFPN LNQNSCINNT LIEPLPLIDR INLNSNLDLN  60
PNPLYAEEGE QEEEEEEEED REVDVDLHIG LPGFGKPSND AKQLKKRNGK EIATYDAGKG  120
IENELSGKAY WIPAPEQILI GFTHFSCHVC FKTFNRYNNL QMHMWGHGSQ YRKGPESLKG  180
TQPRAMLGIP CYCCVEGCRN HIDHPRSKPL KDFRTLQTHY KRKHGHKPFS CRLCGKLLAV  240
KGDWRTHEKN CGKRWVCVCG SDFKHKRSLK DHVKAFGSGH GPYPTGLFEE QASNSSVSET  300
LFF
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.396520.0flower
Expression -- Microarray ? help Back to Top
Source ID
Expression AtlasAT1G34790
AtGenExpressAT1G34790
Expression -- Description ? help Back to Top
Source Description
UniprotDEVELOPMENTAL STAGE: Developing ovules and young seeds. {ECO:0000269|PubMed:11782451}.
UniprotTISSUE SPECIFICITY: Restricted to the endothelium, the innermost cell layer of the seed coat and detected to a lesser extent in the other cell layers of the testa. {ECO:0000269|PubMed:11782451}.
Functional Description ? help Back to Top
Source Description
TAIREncodes a zinc finger protein; involved in photomorphogenesis, flavonoid biosynthesis, flower and seed development.
UniProtMay act as a transcriptional regulator involved in the differentiation of young endothelium. Altered differentiation results in incompetence for pigments synthesis and the lack of condensed tannins in the seed coat (PubMed:21477081). Plays a role in the regulatory network controlling flavonoid accumulation in endothelium cells during seed development (PubMed:21477081). {ECO:0000269|PubMed:11782451, ECO:0000269|PubMed:21477081}.
Function -- GeneRIF ? help Back to Top
  1. TT1 controls early and late steps of flavonoid biosynthesis in the endothelium of Arabidopsis thaliana seeds.
    [PMID: 21477081]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G34790.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT1G61720(A)
Interaction ? help Back to Top
Source Intact With
BioGRIDAT1G34790, AT1G56650
Phenotype -- Disruption Phenotype ? help Back to Top
Source Description
UniProtDISRUPTION PHENOTYPE: Lack of flavanoid pigment accumulation in the seed coat endothelium (transparent testa phenotype). {ECO:0000269|PubMed:21477081}.
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G34790
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF1902980.0AF190298.1 Arabidopsis thaliana ecotype Columbia transparent testa 1 (TT1) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_174737.20.0C2H2 and C2HC zinc fingers superfamily protein
SwissprotQ8VWG30.0TT1_ARATH; Protein TRANSPARENT TESTA 1
TrEMBLA0A178WC090.0A0A178WC09_ARATH; WIP1
STRINGAT1G34790.10.0(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM23928237
Representative plantOGRP4101597
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Sagasser M,Lu GH,Hahlbrock K,Weisshaar B
    A. thaliana TRANSPARENT TESTA 1 is involved in seed coat development and defines the WIP subfamily of plant zinc finger proteins.
    Genes Dev., 2002. 16(1): p. 138-49
    [PMID:11782451]
  3. Nesi N, et al.
    The TRANSPARENT TESTA16 locus encodes the ARABIDOPSIS BSISTER MADS domain protein and is required for proper development and pigmentation of the seed coat.
    Plant Cell, 2002. 14(10): p. 2463-79
    [PMID:12368498]
  4. Debeaujon I, et al.
    Proanthocyanidin-accumulating cells in Arabidopsis testa: regulation of differentiation and role in seed development.
    Plant Cell, 2003. 15(11): p. 2514-31
    [PMID:14555692]
  5. Buer CS,Djordjevic MA
    Architectural phenotypes in the transparent testa mutants of Arabidopsis thaliana.
    J. Exp. Bot., 2009. 60(3): p. 751-63
    [PMID:19129166]
  6. Nesi N, et al.
    The promoter of the Arabidopsis thaliana BAN gene is active in proanthocyanidin-accumulating cells of the Brassica napus seed coat.
    Plant Cell Rep., 2009. 28(4): p. 601-17
    [PMID:19153740]
  7. Appelhagen I, et al.
    Weird fingers: functional analysis of WIP domain proteins.
    FEBS Lett., 2010. 584(14): p. 3116-22
    [PMID:20541552]
  8. Appelhagen I, et al.
    TRANSPARENT TESTA1 interacts with R2R3-MYB factors and affects early and late steps of flavonoid biosynthesis in the endothelium of Arabidopsis thaliana seeds.
    Plant J., 2011. 67(3): p. 406-19
    [PMID:21477081]
  9. Jia L, et al.
    Proanthocyanidins inhibit seed germination by maintaining a high level of abscisic acid in Arabidopsis thaliana.
    J Integr Plant Biol, 2012. 54(9): p. 663-73
    [PMID:22765383]
  10. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  11. Zhou X,Groves NR,Meier I
    Plant nuclear shape is independently determined by the SUN-WIP-WIT2-myosin XI-i complex and CRWN1.
    Nucleus, 2015. 6(2): p. 144-53
    [PMID:25759303]
  12. Lian J, et al.
    Silencing of BnTT1 family genes affects seed flavonoid biosynthesis and alters seed fatty acid composition in Brassica napus.
    Plant Sci., 2017. 254: p. 32-47
    [PMID:27964783]
  13. Shirley BW, et al.
    Analysis of Arabidopsis mutants deficient in flavonoid biosynthesis.
    Plant J., 1995. 8(5): p. 659-71
    [PMID:8528278]