PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G28370.1
Common NameATERF11, ERF076, ERF11, ERF-11, F3M18.20
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 166aa    MW: 18612.1 Da    PI: 9.9064
Description ERF domain protein 11
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G28370.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP259.76.7e-191968255
          AP2  2 gykGVrwdkkrgrWvAeIrd.psengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                 +y+GVr ++ +gr++AeIrd ++    + r++lg+f+t+eeAa+a+++ + +++g
  AT1G28370.1 19 RYRGVRKRP-WGRYAAEIRDpFK----KSRVWLGTFDTPEEAARAYDKRAIEFRG 68
                 6********.**********662....5********************9999988 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF008471.1E-121968IPR001471AP2/ERF domain
PROSITE profilePS5103223.7231976IPR001471AP2/ERF domain
CDDcd000186.60E-321976No hitNo description
SuperFamilySSF541712.42E-221977IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.103.5E-311976IPR001471AP2/ERF domain
SMARTSM003805.8E-341982IPR001471AP2/ERF domain
PRINTSPR003672.6E-112031IPR001471AP2/ERF domain
PRINTSPR003672.6E-114258IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001944Biological Processvasculature development
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009873Biological Processethylene-activated signaling pathway
GO:0051301Biological Processcell division
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000037anatomyshoot apex
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0009005anatomyroot
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009052anatomyflower pedicel
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001185developmental stageplant embryo globular stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007131developmental stageseedling development stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 166 aa     Download sequence    Send to blast
MAPTVKTAAV KTNEGNGVRY RGVRKRPWGR YAAEIRDPFK KSRVWLGTFD TPEEAARAYD  60
KRAIEFRGAK AKTNFPCYNI NAHCLSLTQS LSQSSTVESS FPNLNLGSDS VSSRFPFPKI  120
QVKAGMMVFD ERSESDSSSV VMDVVRYEGR RVVLDLDLNF PPPPEN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A4e-2119821479Ethylene-responsive transcription factor ERF096
Search in ModeBase
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.118340.0root| seed
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO306903880.0
Genevisible261470_at0.0
Expression AtlasAT1G28370-
AtGenExpressAT1G28370-
ATTED-IIAT1G28370-
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the ERF (ethylene response factor) subfamily B-1 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 15 members in this subfamily including ATERF-3, ATERF-4, ATERF-7, and leafy petiole.
UniProtInvolved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. Transcription factor that binds to the GCC-box pathogenesis-related promoter element. Acts as a transcriptional inhibitor and may regulate other AtERFs (By similarity). {ECO:0000250, ECO:0000269|PubMed:11487705}.
Function -- GeneRIF ? help Back to Top
  1. The HY5-AtERF11 regulon is a key factor modulating abscisic acid-regulated ethylene biosynthesis.
    [PMID: 21645149]
  2. Our data demonstrate that dynamic mechanisms exist to fine-tune the stress response and that ERF11 counteracts ERF6 to maintain a balance between plant growth and stress defense.
    [PMID: 25995327]
  3. AtERF11 plays a dual role in promoting internode elongation by inhibiting ethylene biosynthesis and activating GA biosynthesis and signaling pathways.
    [PMID: 27255484]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00164DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G28370.1
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Upstream Regulators) ? help Back to Top
Source Upstream Regulator (A: Activate/R: Repress)
ATRM AT1G32640 (R)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDethylene
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G28370
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAB0558820.0AB055882.1 Arabidopsis thaliana AtERF11 gene for ERF domain protein11, complete cds.
GenBankAC0101550.0AC010155.3 Genomic sequence for Arabidopsis thaliana BAC F3M18 from chromosome I, complete sequence.
GenBankAF3602320.0AF360232.1 Arabidopsis thaliana putative ethylene-responsive element binding factor (At1g28370) mRNA, complete cds.
GenBankAY0867830.0AY086783.1 Arabidopsis thaliana clone 27635 mRNA, complete sequence.
GenBankCP0026840.0CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_174159.21e-121ERF domain protein 11
SwissprotQ9C5I31e-122ERF76_ARATH; Ethylene-responsive transcription factor 11
TrEMBLA0A1P8AP341e-120A0A1P8AP34_ARATH; ERF domain protein 11
STRINGAT1G28370.11e-120(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Ohta M,Matsui K,Hiratsu K,Shinshi H,Ohme-Takagi M
    Repression domains of class II ERF transcriptional repressors share an essential motif for active repression.
    Plant Cell, 2001. 13(8): p. 1959-68
    [PMID:11487705]
  3. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  4. Cluis CP,Mouchel CF,Hardtke CS
    The Arabidopsis transcription factor HY5 integrates light and hormone signaling pathways.
    Plant J., 2004. 38(2): p. 332-47
    [PMID:15078335]
  5. Eulgem T, et al.
    Gene expression signatures from three genetically separable resistance gene signaling pathways for downy mildew resistance.
    Plant Physiol., 2004. 135(2): p. 1129-44
    [PMID:15181204]
  6. Guan Y,Nothnagel EA
    Binding of arabinogalactan proteins by Yariv phenylglycoside triggers wound-like responses in Arabidopsis cell cultures.
    Plant Physiol., 2004. 135(3): p. 1346-66
    [PMID:15235117]
  7. Hass C, et al.
    The response regulator 2 mediates ethylene signalling and hormone signal integration in Arabidopsis.
    EMBO J., 2004. 23(16): p. 3290-302
    [PMID:15282545]
  8. Hampton CR, et al.
    Cesium toxicity in Arabidopsis.
    Plant Physiol., 2004. 136(3): p. 3824-37
    [PMID:15489280]
  9. Wang J, et al.
    Genomewide nonadditive gene regulation in Arabidopsis allotetraploids.
    Genetics, 2006. 172(1): p. 507-17
    [PMID:16172500]
  10. McGrath KC, et al.
    Repressor- and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression.
    Plant Physiol., 2005. 139(2): p. 949-59
    [PMID:16183832]
  11. Lee BH,Henderson DA,Zhu JK
    The Arabidopsis cold-responsive transcriptome and its regulation by ICE1.
    Plant Cell, 2005. 17(11): p. 3155-75
    [PMID:16214899]
  12. Suzuki N, et al.
    Enhanced tolerance to environmental stress in transgenic plants expressing the transcriptional coactivator multiprotein bridging factor 1c.
    Plant Physiol., 2005. 139(3): p. 1313-22
    [PMID:16244138]
  13. Vergnolle C, et al.
    The cold-induced early activation of phospholipase C and D pathways determines the response of two distinct clusters of genes in Arabidopsis cell suspensions.
    Plant Physiol., 2005. 139(3): p. 1217-33
    [PMID:16258011]
  14. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  15. Nemhauser JL,Hong F,Chory J
    Different plant hormones regulate similar processes through largely nonoverlapping transcriptional responses.
    Cell, 2006. 126(3): p. 467-75
    [PMID:16901781]
  16. Ma S,Bohnert HJ
    Integration of Arabidopsis thaliana stress-related transcript profiles, promoter structures, and cell-specific expression.
    Genome Biol., 2007. 8(4): p. R49
    [PMID:17408486]
  17. Hectors K,Prinsen E,De Coen W,Jansen MA,Guisez Y
    Arabidopsis thaliana plants acclimated to low dose rates of ultraviolet B radiation show specific changes in morphology and gene expression in the absence of stress symptoms.
    New Phytol., 2007. 175(2): p. 255-70
    [PMID:17587374]
  18. Dombrecht B, et al.
    MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis.
    Plant Cell, 2007. 19(7): p. 2225-45
    [PMID:17616737]
  19. Song YH, et al.
    DNA-binding study identifies C-box and hybrid C/G-box or C/A-box motifs as high-affinity binding sites for STF1 and LONG HYPOCOTYL5 proteins.
    Plant Physiol., 2008. 146(4): p. 1862-77
    [PMID:18287490]
  20. Veyres N, et al.
    The Arabidopsis sweetie mutant is affected in carbohydrate metabolism and defective in the control of growth, development and senescence.
    Plant J., 2008. 55(4): p. 665-86
    [PMID:18452589]
  21. Li Z, et al.
    The ethylene response factor AtERF11 that is transcriptionally modulated by the bZIP transcription factor HY5 is a crucial repressor for ethylene biosynthesis in Arabidopsis.
    Plant J., 2011. 68(1): p. 88-99
    [PMID:21645149]
  22. Chen YY,Wang LF,Dai LJ,Yang SG,Tian WM
    Characterization of HbEREBP1, a wound-responsive transcription factor gene in laticifers of Hevea brasiliensis Muell. Arg.
    Mol. Biol. Rep., 2012. 39(4): p. 3713-9
    [PMID:21761140]
  23. Causier B,Ashworth M,Guo W,Davies B
    The TOPLESS interactome: a framework for gene repression in Arabidopsis.
    Plant Physiol., 2012. 158(1): p. 423-38
    [PMID:22065421]
  24. Etchells JP,Provost CM,Turner SR
    Plant vascular cell division is maintained by an interaction between PXY and ethylene signalling.
    PLoS Genet., 2012. 8(11): p. e1002997
    [PMID:23166504]
  25. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  26. Dubois M, et al.
    The ETHYLENE RESPONSE FACTORs ERF6 and ERF11 Antagonistically Regulate Mannitol-Induced Growth Inhibition in Arabidopsis.
    Plant Physiol., 2015. 169(1): p. 166-79
    [PMID:25995327]
  27. Xiao D, et al.
    SENESCENCE-SUPPRESSED PROTEIN PHOSPHATASE Directly Interacts with the Cytoplasmic Domain of SENESCENCE-ASSOCIATED RECEPTOR-LIKE KINASE and Negatively Regulates Leaf Senescence in Arabidopsis.
    Plant Physiol., 2015. 169(2): p. 1275-91
    [PMID:26304848]
  28. Zhou X, et al.
    The ERF11 Transcription Factor Promotes Internode Elongation by Activating Gibberellin Biosynthesis and Signaling.
    Plant Physiol., 2016. 171(4): p. 2760-70
    [PMID:27255484]
  29. Riechmann JL,Meyerowitz EM
    The AP2/EREBP family of plant transcription factors.
    Biol. Chem., 1998. 379(6): p. 633-46
    [PMID:9687012]