PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G21910.1
Common NameDREB26, ERF012, T26F17.14
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 230aa    MW: 25476.2 Da    PI: 7.7563
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G21910.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP256.66.6e-184898155
          AP2  1 sgykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                 ++ykGVr ++ +g+Wv+eIr p   ++++r++lg++ tae Aa+a++ a ++l+g
  AT1G21910.1 48 KKYKGVRMRS-WGSWVSEIRAP---NQKTRIWLGSYSTAEAAARAYDVALLCLKG 98
                 59*****998.**********9...336************************998 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5103222.0149106IPR001471AP2/ERF domain
SuperFamilySSF541713.07E-2049108IPR016177DNA-binding domain
Gene3DG3DSA:3.30.730.101.9E-3049108IPR001471AP2/ERF domain
SMARTSM003801.6E-3549112IPR001471AP2/ERF domain
PfamPF008474.4E-114998IPR001471AP2/ERF domain
PRINTSPR003675.4E-95061IPR001471AP2/ERF domain
CDDcd000188.02E-3050108No hitNo description
PRINTSPR003675.4E-97288IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009751Biological Processresponse to salicylic acid
GO:0009753Biological Processresponse to jasmonic acid
GO:0009873Biological Processethylene-activated signaling pathway
GO:0034605Biological Processcellular response to heat
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0071497Biological Processcellular response to freezing
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0000003anatomywhole plant
PO:0000013anatomycauline leaf
PO:0000014anatomyrosette leaf
PO:0000037anatomyshoot apex
PO:0000056anatomyflower bud
PO:0000230anatomyinflorescence meristem
PO:0000293anatomyguard cell
PO:0008019anatomyleaf lamina base
PO:0009001anatomyfruit
PO:0009005anatomyroot
PO:0009006anatomyshoot system
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009025anatomyvascular leaf
PO:0009029anatomystamen
PO:0009030anatomycarpel
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0009047anatomystem
PO:0009049anatomyinflorescence
PO:0009052anatomyflower pedicel
PO:0009066anatomyanther
PO:0020003anatomyplant ovule
PO:0020030anatomycotyledon
PO:0020038anatomypetiole
PO:0020100anatomyhypocotyl
PO:0020137anatomyleaf apex
PO:0025022anatomycollective leaf structure
PO:0025281anatomypollen
PO:0001054developmental stagevascular leaf senescent stage
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0001081developmental stagemature plant embryo stage
PO:0001185developmental stageplant embryo globular stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007064developmental stageLP.12 twelve leaves visible stage
PO:0007095developmental stageLP.08 eight leaves visible stage
PO:0007098developmental stageLP.02 two leaves visible stage
PO:0007103developmental stageLP.10 ten leaves visible stage
PO:0007115developmental stageLP.04 four leaves visible stage
PO:0007123developmental stageLP.06 six leaves visible stage
PO:0007131developmental stageseedling development stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 230 aa     Download sequence    Send to blast
MVKQERKIQT SSTKKEMPLS SSPSSSSSSS SSSSSSSCKN KNKKSKIKKY KGVRMRSWGS  60
WVSEIRAPNQ KTRIWLGSYS TAEAAARAYD VALLCLKGPQ ANLNFPTSSS SHHLLDNLLD  120
ENTLLSPKSI QRVAAQAANS FNHFAPTSSA VSSPSDHDHH HDDGMQSLMG SFVDNHVSLM  180
DSTSSWYDDH NGMFLFDNGA PFNYSPQLNS TTMLDEYFYE DADIPLWSFN
Expression -- UniGene ? help Back to Top
UniGene ID E-value Expressed in
At.416360.0seed| silique
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible260856_at0.0
Expression AtlasAT1G21910-
AtGenExpressAT1G21910-
ATTED-IIAT1G21910-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Expressed cotyledons, ovules and seeds of immature siliques. {ECO:0000269|PubMed:21069430}.
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the DREB subfamily A-5 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 15 members in this subfamily including RAP2.1, RAP2.9 and RAP2.10.
UniProtTranscriptional activator involved in the regulation of plant development and tolerance to abiotic stresses (PubMed:21069430). Involved in salt and osmotic stress response pathways. May be regulated by the stress-related genes RD29A, RD22, DREB1A or P5CS during stress response (PubMed:27137403). Binds to the GCC-box pathogenesis-related promoter element. May be involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways (By similarity). {ECO:0000250, ECO:0000269|PubMed:21069430, ECO:0000269|PubMed:27137403}.
Function -- GeneRIF ? help Back to Top
  1. Data demonstrate that RAP2.6 (At1g43160), RAP2.6L (At5g13330), DREB 26 (At1g21910) and DREB19 (At2g38340) are transactivators, they exhibit tissue specific expression, and participate in developmental processes as well as biotic/abiotic stress signaling.
    [PMID: 21069430]
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00156DAP27203113Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G21910.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by jasmonate (JA) and ethylene. Down-regulated by freezing and heat stresses. {ECO:0000269|PubMed:21069430}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G21910
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAC0134820.0AC013482.2 Genomic sequence for Arabidopsis thaliana BAC T26F17 from chromosome I, complete sequence.
GenBankAK1766790.0AK176679.1 Arabidopsis thaliana mRNA for TINY like protein, complete cds, clone: RAFL25-22-A03.
GenBankBT0246160.0BT024616.1 Arabidopsis thaliana At1g21910 mRNA, complete cds.
GenBankCP0026840.0CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_173609.11e-169Integrase-type DNA-binding superfamily protein
SwissprotQ9SFE41e-170ERF12_ARATH; Ethylene-responsive transcription factor ERF012
TrEMBLA0A178W3Q91e-168A0A178W3Q9_ARATH; DREB26
STRINGAT1G21910.11e-169(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM29992767
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Dal Bosco C, et al.
    Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.
    J. Biol. Chem., 2004. 279(2): p. 1060-9
    [PMID:14576160]
  3. Rizhsky L,Davletova S,Liang H,Mittler R
    The zinc finger protein Zat12 is required for cytosolic ascorbate peroxidase 1 expression during oxidative stress in Arabidopsis.
    J. Biol. Chem., 2004. 279(12): p. 11736-43
    [PMID:14722088]
  4. Guan Y,Nothnagel EA
    Binding of arabinogalactan proteins by Yariv phenylglycoside triggers wound-like responses in Arabidopsis cell cultures.
    Plant Physiol., 2004. 135(3): p. 1346-66
    [PMID:15235117]
  5. Wang R, et al.
    Genomic analysis of the nitrate response using a nitrate reductase-null mutant of Arabidopsis.
    Plant Physiol., 2004. 136(1): p. 2512-22
    [PMID:15333754]
  6. Hilson P, et al.
    Versatile gene-specific sequence tags for Arabidopsis functional genomics: transcript profiling and reverse genetics applications.
    Genome Res., 2004. 14(10B): p. 2176-89
    [PMID:15489341]
  7. Lee D,Polisensky DH,Braam J
    Genome-wide identification of touch- and darkness-regulated Arabidopsis genes: a focus on calmodulin-like and XTH genes.
    New Phytol., 2005. 165(2): p. 429-44
    [PMID:15720654]
  8. Suzuki N, et al.
    Enhanced tolerance to environmental stress in transgenic plants expressing the transcriptional coactivator multiprotein bridging factor 1c.
    Plant Physiol., 2005. 139(3): p. 1313-22
    [PMID:16244138]
  9. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  10. Wagner R,Pfannschmidt T
    Eukaryotic transcription factors in plastids--Bioinformatic assessment and implications for the evolution of gene expression machineries in plants.
    Gene, 2006. 381: p. 62-70
    [PMID:16934950]
  11. Lee J, et al.
    Analysis of transcription factor HY5 genomic binding sites revealed its hierarchical role in light regulation of development.
    Plant Cell, 2007. 19(3): p. 731-49
    [PMID:17337630]
  12. Sottosanto JB,Saranga Y,Blumwald E
    Impact of AtNHX1, a vacuolar Na+/H+ antiporter, upon gene expression during short- and long-term salt stress in Arabidopsis thaliana.
    BMC Plant Biol., 2007. 7: p. 18
    [PMID:17411438]
  13. Kleine T,Kindgren P,Benedict C,Hendrickson L,Strand A
    Genome-wide gene expression analysis reveals a critical role for CRYPTOCHROME1 in the response of Arabidopsis to high irradiance.
    Plant Physiol., 2007. 144(3): p. 1391-406
    [PMID:17478635]
  14. Ramel F, et al.
    Genome-wide interacting effects of sucrose and herbicide-mediated stress in Arabidopsis thaliana: novel insights into atrazine toxicity and sucrose-induced tolerance.
    BMC Genomics, 2007. 8: p. 450
    [PMID:18053238]
  15. Ferreira FJ,Guo C,Coleman JR
    Reduction of plastid-localized carbonic anhydrase activity results in reduced Arabidopsis seedling survivorship.
    Plant Physiol., 2008. 147(2): p. 585-94
    [PMID:18434607]
  16. Krishnaswamy SS, et al.
    Transcriptional profiling of pea ABR17 mediated changes in gene expression in Arabidopsis thaliana.
    BMC Plant Biol., 2008. 8: p. 91
    [PMID:18783601]
  17. Krishnaswamy S,Verma S,Rahman MH,Kav NN
    Functional characterization of four APETALA2-family genes (RAP2.6, RAP2.6L, DREB19 and DREB26) in Arabidopsis.
    Plant Mol. Biol., 2011. 75(1-2): p. 107-27
    [PMID:21069430]
  18. Gaudinier A, et al.
    Enhanced Y1H assays for Arabidopsis.
    Nat. Methods, 2011. 8(12): p. 1053-5
    [PMID:22037706]
  19. Kazama D,Kurusu T,Mitsuda N,Ohme-Takagi M,Tada Y
    Involvement of elevated proline accumulation in enhanced osmotic stress tolerance in Arabidopsis conferred by chimeric repressor gene silencing technology.
    Plant Signal Behav, 2014. 9(3): p. e28211
    [PMID:24614501]
  20. Kazama D, et al.
    Identification of Chimeric Repressors that Confer Salt and Osmotic Stress Tolerance in Arabidopsis.
    Plants (Basel), 2013. 2(4): p. 769-85
    [PMID:27137403]