PlantTFDB
Plant Transcription Factor Database
v5.0
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G06170.2
Common NameBHLH89, EN24, F9P14.3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family bHLH
Protein Properties Length: 420aa    MW: 47032.7 Da    PI: 5.7277
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G06170.2genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH32.81.3e-10220261854
                  HHHHHHHHHHHHHHHHHCTSCCC...TTS-STCHHHHHHHHHHHHHH CS
          HLH   8 rErrRRdriNsafeeLrellPkaskapskKlsKaeiLekAveYIksL 54 
                   Er RR + +++f  L+ l+P++     +K++ a+i+ +A++YIk+L
  AT1G06170.2 220 TERERRVHFKDRFGDLKNLIPNP-----TKNDRASIVGEAIDYIKEL 261
                  7**********************.....9****************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
CDDcd000831.65E-9210263No hitNo description
SuperFamilySSF474593.22E-12211277IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PROSITE profilePS5088813.827212261IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.102.9E-10212279IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003539.4E-7218267IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
PfamPF000106.3E-8220261IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009555Biological Processpollen development
GO:0048658Biological Processanther wall tapetum development
GO:0052543Biological Processcallose deposition in cell wall
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Plant Ontology ? help Back to Top
PO Term PO Category PO Description
PO:0009009anatomyplant embryo
PO:0009010anatomyseed
PO:0009031anatomysepal
PO:0009032anatomypetal
PO:0009046anatomyflower
PO:0025022anatomycollective leaf structure
PO:0001078developmental stageplant embryo cotyledonary stage
PO:0004507developmental stageplant embryo bilateral stage
PO:0007611developmental stagepetal differentiation and expansion stage
PO:0007616developmental stageflowering stage
Sequence ? help Back to Top
Protein Sequence    Length: 420 aa     Download sequence    Send to blast
MGGGGMFEEI GCFDPNAPAE MTAESSFSPS EPPPTITVIG SNSNSNCSLE DLSAFHLSPQ  60
DSSLPASASA YAHQLHINAT PNCDHQFQSS MHQTLQDPSY AQQSNHWDNG YQDFVNLGPN  120
HTTPDLLSLL QLPRSSLPPF ANPSIQDIIM TTSSSVAAYD PLFHLNFPLQ PPNGSFMGVD  180
QDQTETNQGV NLMYDEENNN LDDGLNRKGR GSKKRKIFPT ERERRVHFKD RFGDLKNLIP  240
NPTKNDRASI VGEAIDYIKE LLRTIDEFKL LVEKKRVKQR NREGDDVVDE NFKAQSEVVE  300
QCLINKKNNA LRCSWLKRKS KFTDVDVRII DDEVTIKIVQ KKKINCLLFV SKVVDQLELD  360
LHHVAGAQIG EHHSFLFNAK ISEGSSVYAS AIADRVMEVL KKQYMEALSA NNGYHCYSSD
Expression -- Microarray ? help Back to Top
Source ID E-value
Genevisible257491_at0.0
Expression AtlasAT1G06170-
AtGenExpressAT1G06170-
ATTED-IIAT1G06170-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Flowers. {ECO:0000269|PubMed:12679534}.
Function -- GeneRIF ? help Back to Top
  1. bHLH010, bHLH089 and bHLH091 together are important for the normal transcriptome of the developing Arabidopsis anther, possibly by forming a feed-forward loop with DYT1.
    [PMID: 26216374]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G06170.2
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Interaction ? help Back to Top
Source Intact With
BioGRIDAT1G14920
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G06170
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAF4886190.0AF488619.1 Arabidopsis thaliana clone bHLH089 putative bHLH transcription factor mRNA, complete cds.
GenBankBT0042620.0BT004262.1 Arabidopsis thaliana clone RAFL15-18-B21 (R20806) putative bHLH protein (At1g06170) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_172107.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
RefseqNP_973769.10.0basic helix-loop-helix (bHLH) DNA-binding superfamily protein
SwissprotQ9LND00.0BH089_ARATH; Transcription factor bHLH89
TrEMBLA0A178WK970.0A0A178WK97_ARATH; Uncharacterized protein
STRINGAT1G06170.20.0(Arabidopsis thaliana)
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. Heim MA, et al.
    The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.
    Mol. Biol. Evol., 2003. 20(5): p. 735-47
    [PMID:12679534]
  3. Toledo-Ortiz G,Huq E,Quail PH
    The Arabidopsis basic/helix-loop-helix transcription factor family.
    Plant Cell, 2003. 15(8): p. 1749-70
    [PMID:12897250]
  4. Yamada K, et al.
    Empirical analysis of transcriptional activity in the Arabidopsis genome.
    Science, 2003. 302(5646): p. 842-6
    [PMID:14593172]
  5. Bailey PC, et al.
    Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.
    Plant Cell, 2003. 15(11): p. 2497-502
    [PMID:14600211]
  6. Zhang W, et al.
    Regulation of Arabidopsis tapetum development and function by DYSFUNCTIONAL TAPETUM1 (DYT1) encoding a putative bHLH transcription factor.
    Development, 2006. 133(16): p. 3085-95
    [PMID:16831835]
  7. Xu J, et al.
    The ABORTED MICROSPORES regulatory network is required for postmeiotic male reproductive development in Arabidopsis thaliana.
    Plant Cell, 2010. 22(1): p. 91-107
    [PMID:20118226]
  8. Feng B, et al.
    Regulation of the Arabidopsis anther transcriptome by DYT1 for pollen development.
    Plant J., 2012. 72(4): p. 612-24
    [PMID:22775442]
  9. Efroni I, et al.
    Regulation of leaf maturation by chromatin-mediated modulation of cytokinin responses.
    Dev. Cell, 2013. 24(4): p. 438-45
    [PMID:23449474]
  10. Mar
    Large-scale identification of gibberellin-related transcription factors defines group VII ETHYLENE RESPONSE FACTORS as functional DELLA partners.
    Plant Physiol., 2014. 166(2): p. 1022-32
    [PMID:25118255]
  11. Zhu E, et al.
    The DYT1-interacting proteins bHLH010, bHLH089 and bHLH091 are redundantly required for Arabidopsis anther development and transcriptome.
    Plant J., 2015. 83(6): p. 976-90
    [PMID:26216374]
  12. Cui J, et al.
    Feedback Regulation of DYT1 by Interactions with Downstream bHLH Factors Promotes DYT1 Nuclear Localization and Anther Development.
    Plant Cell, 2016. 28(5): p. 1078-93
    [PMID:27113773]
  13. Ezer D, et al.
    The G-Box Transcriptional Regulatory Code in Arabidopsis.
    Plant Physiol., 2017. 175(2): p. 628-640
    [PMID:28864470]