PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AT1G04370.1
Common NameATERF14, ERF097, ERF14, ERF-14, F19P19.19
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Family ERF
Protein Properties Length: 133aa    MW: 14743 Da    PI: 7.7475
Description Ethylene-responsive element binding factor 14
Gene Model
Gene Model ID Type Source Coding Sequence
AT1G04370.1genomeTAIRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP263.54.5e-201969255
          AP2  2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55
                 +y+GVr+++ +g+++AeIrd ++ g   r++lg+f+tae+Aa+a+++a+ +++g
  AT1G04370.1 19 KYRGVRRRP-WGKYAAEIRDSRKHG--ERVWLGTFDTAEDAARAYDRAAYSMRG 69
                 8********.**********65443..*************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.730.103.1E-321979IPR001471AP2/ERF domain
SuperFamilySSF541719.81E-241979IPR016177DNA-binding domain
CDDcd000184.56E-181978No hitNo description
PROSITE profilePS5103223.9471977IPR001471AP2/ERF domain
SMARTSM003803.0E-351983IPR001471AP2/ERF domain
PfamPF008472.5E-141969IPR001471AP2/ERF domain
PRINTSPR003678.8E-122031IPR001471AP2/ERF domain
PRINTSPR003678.8E-124359IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0006952Biological Processdefense response
GO:0009873Biological Processethylene-activated signaling pathway
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 133 aa     Download sequence    Send to blast
MDQGGRSSGS GGGGAEQGKY RGVRRRPWGK YAAEIRDSRK HGERVWLGTF DTAEDAARAY  60
DRAAYSMRGK AAILNFPHEY NMGTGSSSTA ANSSSSSQQV FEFEYLDDSV LDELLEYGEN  120
YNKTHNINMG KRQ
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5wx9_A6e-5411101114Ethylene-responsive transcription factor ERF096
Search in ModeBase
Expression -- Microarray ? help Back to Top
Source ID E-value
GEO183903850.0
Expression AtlasAT1G04370-
AtGenExpressAT1G04370-
Expression -- Description ? help Back to Top
Source Description
UniprotTISSUE SPECIFICITY: Ubiquitously expressed after ethylene treatment. {ECO:0000269|PubMed:11950980}.
Functional Description ? help Back to Top
Source Description
TAIRencodes a member of the ERF (ethylene response factor) subfamily B-3 of ERF/AP2 transcription factor family. The protein contains one AP2 domain. There are 18 members in this subfamily including ATERF-1, ATERF-2, AND ATERF-5.
UniProtActs as a transcriptional activator. Binds to the GCC-box pathogenesis-related promoter element. Involved in the regulation of gene expression by stress factors and by components of stress signal transduction pathways. {ECO:0000269|PubMed:11950980}.
Function -- GeneRIF ? help Back to Top
  1. AtERF14 gene is important for ethylene responses and pathogen resistance. [AtERF14]
    [PMID: 17114278]
  2. ERF9 and ERF14 are involved in the interaction between Piriformospora and Arabidopsis. Inactivation of these genes diminishes the P. indica-induced growth promotion and activates the expression of the PATHOGENESIS-RELATED genes.
    [PMID: 20505369]
Cis-element ? help Back to Top
SourceLink
PlantRegMapAT1G04370.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by Pseudomonas syringae tomato (both virulent and avirulent avrRpt2 strains). Not affected by methyl jasmonate (MeJA), ethylene or salicylic acid (SA). {ECO:0000269|PubMed:11950980}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Regulation -- ATRM (Manually Curated Target Genes) ? help Back to Top
Source Target Gene (A: Activate/R: Repress)
ATRM AT2G44840(A), AT3G23240(A)
Regulation -- Hormone ? help Back to Top
Source Hormone
AHDethylene
Phenotype -- Mutation ? help Back to Top
Source ID
T-DNA ExpressAT1G04370
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankBT0264210.0BT026421.1 Arabidopsis thaliana At1g04370 mRNA, complete cds.
GenBankCP0026840.0CP002684.1 Arabidopsis thaliana chromosome 1 sequence.
GenBankF19P190.0AC000104.1 Sequence of BAC F19P19 from Arabidopsis thaliana chromosome 1, complete sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_171932.11e-94Ethylene-responsive element binding factor 14
SwissprotP938221e-95ERF97_ARATH; Ethylene-responsive transcription factor 14
TrEMBLC0SUS63e-93C0SUS6_ARATH; Uncharacterized protein At1g04370 (Fragment)
STRINGAT1G04370.16e-94(Arabidopsis thaliana)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM10281650
Representative plantOGRP6161718
Publications ? help Back to Top
  1. Riechmann JL, et al.
    Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.
    Science, 2000. 290(5499): p. 2105-10
    [PMID:11118137]
  2. O
    Identification of Arabidopsis ethylene-responsive element binding factors with distinct induction kinetics after pathogen infection.
    Plant Physiol., 2002. 128(4): p. 1313-22
    [PMID:11950980]
  3. Wilson IW,Kennedy GC,Peacock JW,Dennis ES
    Microarray analysis reveals vegetative molecular phenotypes of Arabidopsis flowering-time mutants.
    Plant Cell Physiol., 2005. 46(8): p. 1190-201
    [PMID:15908439]
  4. McGrath KC, et al.
    Repressor- and activator-type ethylene response factors functioning in jasmonate signaling and disease resistance identified via a genome-wide screen of Arabidopsis transcription factor gene expression.
    Plant Physiol., 2005. 139(2): p. 949-59
    [PMID:16183832]
  5. Nakano T,Suzuki K,Fujimura T,Shinshi H
    Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
    Plant Physiol., 2006. 140(2): p. 411-32
    [PMID:16407444]
  6. Oñate-Sánchez L,Anderson JP,Young J,Singh KB
    AtERF14, a member of the ERF family of transcription factors, plays a nonredundant role in plant defense.
    Plant Physiol., 2007. 143(1): p. 400-9
    [PMID:17114278]
  7. Dombrecht B, et al.
    MYC2 differentially modulates diverse jasmonate-dependent functions in Arabidopsis.
    Plant Cell, 2007. 19(7): p. 2225-45
    [PMID:17616737]
  8. Pré M, et al.
    The AP2/ERF domain transcription factor ORA59 integrates jasmonic acid and ethylene signals in plant defense.
    Plant Physiol., 2008. 147(3): p. 1347-57
    [PMID:18467450]
  9. Camehl I,Oelm
    Do ethylene response factorS9 and -14 repress PR gene expression in the interaction between Piriformospora indica and Arabidopsis?
    Plant Signal Behav, 2010. 5(8): p. 932-6
    [PMID:20505369]
  10. Anderson JP,Singh KB
    Interactions of Arabidopsis and M. truncatula with the same pathogens differ in dependence on ethylene and ethylene response factors.
    Plant Signal Behav, 2011. 6(4): p. 551-2
    [PMID:21389781]
  11. Hu Y,Shen Y,Conde E Silva N,Zhou DX
    The role of histone methylation and H2A.Z occupancy during rapid activation of ethylene responsive genes.
    PLoS ONE, 2011. 6(11): p. e28224
    [PMID:22140554]
  12. Moffat CS, et al.
    ERF5 and ERF6 play redundant roles as positive regulators of JA/Et-mediated defense against Botrytis cinerea in Arabidopsis.
    PLoS ONE, 2012. 7(4): p. e35995
    [PMID:22563431]
  13. Jin J, et al.
    An Arabidopsis Transcriptional Regulatory Map Reveals Distinct Functional and Evolutionary Features of Novel Transcription Factors.
    Mol. Biol. Evol., 2015. 32(7): p. 1767-73
    [PMID:25750178]
  14. Riechmann JL,Meyerowitz EM
    The AP2/EREBP family of plant transcription factors.
    Biol. Chem., 1998. 379(6): p. 633-46
    [PMID:9687012]