PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_944_f_2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family WRKY
Protein Properties Length: 566aa    MW: 62072.1 Da    PI: 7.1261
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_944_f_2genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY76.33.6e-24217272159
                   ---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
          WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                   ++Dg++WrKYGqK  kg+++pr+YYrCt + +Cpv    +r +ed +++++tYeg+Hnh+
  Neem_944_f_2 217 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVSpTCPV----QRWSEDMSILITTYEGTHNHP 272
                   58**************************999**96....56888***************7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.0E-24202274IPR003657WRKY domain
SuperFamilySSF1182903.53E-22210274IPR003657WRKY domain
PROSITE profilePS5081123.204212274IPR003657WRKY domain
SMARTSM007746.4E-28217273IPR003657WRKY domain
PfamPF031061.2E-20218272IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 566 aa     Download sequence    Send to blast
MENNQDNKSL LGKACMEEKT KKSNGEEEEG RDVHAKTQKE EQLKSAKAKV GEIREENERL  60
KLLLARMVKD YQSLQNHFLN ILQQEEIKKS KGISPAHQEN EELELVSLSL GRASSEPKKL  120
DEKKNNNLIL GKEDEKCKEG LTLGLDCRFE FNSTELAEKN PSSENTFEEL KEEEPTEIWP  180
PSKILKTVRS EDEEVLQQTN LKKARVSVRA RCDTPTMNDG CQWRKYGQKI AKGNPCPRAY  240
YRCTVSPTCP VQRWSEDMSI LITTYEGTHN HPLPVSATAM ASTTSAAASM LQCRASTSQP  300
GFGTSLSASD STSTSADLHG LNFTSSENAK PHLFYFPNSS ISTSNSHPTI VLDLTAPTAF  360
SHFNRLTSAP RYNSPTCLNF SAPSSANSFE PSKTLQTSWS NGYSSYGTLN SYNKNIHVGA  420
LNLAKQQKPR EHINQPFTQM NNLSPQQSLT ETIAATTKVI TSNPSFQSAL AAAISSYIGN  480
AGSEAHQNRV GVEVSGLNLT WGESFPIKPA DSSAQNGMGC ASTFLNKLLS CNNPQQQGNL  540
SIFPPNSLPF STSKSASGSP ADGKDH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A4e-18204274174WRKY transcription factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269|PubMed:20409007, ECO:0000269|PubMed:24884371}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269|PubMed:20409007}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024042177.10.0probable WRKY transcription factor 36 isoform X1
SwissprotA0A3Q7GFB51e-110WK72A_SOLLC; WRKY transcription factor 72A
TrEMBLA0A2C9WM200.0A0A2C9WM20_MANES; Uncharacterized protein
STRINGXP_006483224.10.0(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM29592868
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G15130.11e-68WRKY DNA-binding protein 72
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Spyropoulou EA,Haring MA,Schuurink RC
    RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters.
    BMC Genomics, 2014. 15: p. 402
    [PMID:24884371]