PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_9116_f_3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family Dof
Protein Properties Length: 309aa    MW: 33967 Da    PI: 6.9616
Description Dof family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_9116_f_3genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-Dof128.32.2e-4051111262
         zf-Dof   2 kekalkcprCdstntkfCyynnyslsqPryfCkaCrryWtkGGalrnvPvGggrrknkkss 62 
                    +++alkcprCdst+tkfCyynnyslsqPryfCk+CrryWtkGG+lrn+PvGgg+rknkk+s
  Neem_9116_f_3  51 HDQALKCPRCDSTHTKFCYYNNYSLSQPRYFCKTCRRYWTKGGTLRNIPVGGGCRKNKKVS 111
                    7899******************************************************987 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
ProDomPD0074785.0E-2845105IPR003851Zinc finger, Dof-type
PfamPF027019.7E-3452109IPR003851Zinc finger, Dof-type
PROSITE profilePS5088429.18955109IPR003851Zinc finger, Dof-type
PROSITE patternPS0136105793IPR003851Zinc finger, Dof-type
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0010067Biological Processprocambium histogenesis
GO:0010087Biological Processphloem or xylem histogenesis
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 309 aa     Download sequence    Send to blast
MGLTSLQVCM DSSDWLQGSI HEESGLDSSS PSGDLLTCSR PLMERRLRPQ HDQALKCPRC  60
DSTHTKFCYY NNYSLSQPRY FCKTCRRYWT KGGTLRNIPV GGGCRKNKKV SSKKSNDQSI  120
NQNPASSSHN PTDLQLSFPE MQFSHLGNIL GTHGTLANPN FMDTKYNAML ENSRPIDFME  180
SKLEAIVGSS RNYDFMGNNE LGMVGGLGNL GHHGLTPNVH NLCSPFGMSL EGNGGTFIDT  240
CQRLMLPYDA NEDQNAIDVK PNTKMLSLDW QDQGCSDVGK DAFGYLGNLG PSWSGMMNGY  300
GSSAANSLV
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that binds specifically to a 5'-AA[AG]G-3' consensus core sequence (By similarity). Promotes expression (PubMed:19915089). The PEAR proteins (e.g. DOF2.4, DOF5.1, DOF3.2, DOF1.1, DOF5.6 and DOF5.3) activate gene expression that promotes radial growth of protophloem sieve elements (PubMed:30626969). Involved in the regulation of interfascicular cambium formation and vascular tissue development, particularly at a very early stage during inflorescence stem development; promotes both cambium activity and phloem specification, but prevents xylem specification (PubMed:19915089). {ECO:0000250|UniProtKB:Q9M2U1, ECO:0000269|PubMed:19915089, ECO:0000269|PubMed:30626969}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00580DAPTransfer from AT5G62940Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006439825.10.0dof zinc finger protein DOF5.6
RefseqXP_024954523.10.0dof zinc finger protein DOF5.6
SwissprotQ9FM034e-62DOF56_ARATH; Dof zinc finger protein DOF5.6
TrEMBLA0A061FV520.0A0A061FV52_THECC; Dof-type zinc finger DNA-binding family protein isoform 1
TrEMBLA0A067FQG50.0A0A067FQG5_CITSI; Uncharacterized protein
TrEMBLA0A2H5P4T40.0A0A2H5P4T4_CITUN; Uncharacterized protein
TrEMBLV4TN030.0V4TN03_9ROSI; Uncharacterized protein
STRINGXP_006476784.10.0(Citrus sinensis)
STRINGEOY207320.0(Theobroma cacao)
STRINGXP_006439825.10.0(Citrus clementina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM63742746
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G62940.13e-50Dof family protein
Publications ? help Back to Top
  1. Miyashima S, et al.
    Mobile PEAR transcription factors integrate positional cues to prime cambial growth.
    Nature, 2019. 565(7740): p. 490-494
    [PMID:30626969]