PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_35863_f_1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family C2H2
Protein Properties Length: 350aa    MW: 40433.1 Da    PI: 8.9746
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_35863_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H221.27.5e-076485223
                    EETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  2 kCpdCgksFsrksnLkrHirtH 23
                    +C+ Cg +F+ + +Lk+H+++H
  Neem_35863_f_1 64 TCEECGATFKKPAYLKQHMQSH 85
                    6*******************99 PP

2zf-C2H216.52.4e-05101125123
                     EEET..TTTEEESSHHHHHHHHHHT CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                     + C+  dC+ s++rk++L+rH+  H
  Neem_35863_f_1 101 FICSvdDCHASYRRKDHLTRHLLQH 125
                     789999***************9887 PP

3zf-C2H214.78.7e-05130155123
                     EEET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                     ++Cp  +C++ F+ + n+krH +  H
  Neem_35863_f_1 130 FRCPieNCSREFTIQGNMKRHVKEfH 155
                     89********************9988 PP

4zf-C2H214.79e-05244267323
                     ET..TTTEEESSHHHHHHHHHH.T CS
         zf-C2H2   3 Cp..dCgksFsrksnLkrHirt.H 23 
                     C    C  sFs+ksnL++H +  H
  Neem_35863_f_1 244 CMfkGCRHSFSTKSNLQQHVKAvH 267
                     66779***************9886 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576677.52E-81785No hitNo description
PROSITE profilePS501578.8911946IPR007087Zinc finger, C2H2
SMARTSM00355281941IPR015880Zinc finger, C2H2-like
PROSITE profilePS5015711.0746390IPR007087Zinc finger, C2H2
SMARTSM003550.00296385IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.606.1E-664100IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS0002806585IPR007087Zinc finger, C2H2
SuperFamilySSF576671.99E-697127No hitNo description
PROSITE profilePS501579.494101130IPR007087Zinc finger, C2H2
SMARTSM003550.0093101125IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.608.0E-10101127IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280103125IPR007087Zinc finger, C2H2
SuperFamilySSF576672.42E-6128156No hitNo description
Gene3DG3DSA:3.30.160.601.2E-5128152IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.242130160IPR007087Zinc finger, C2H2
SMARTSM003550.0096130155IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280132155IPR007087Zinc finger, C2H2
SMARTSM0035512184209IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280186209IPR007087Zinc finger, C2H2
SMARTSM0035510212233IPR015880Zinc finger, C2H2-like
SuperFamilySSF576675.78E-8225279No hitNo description
PROSITE profilePS5015711.198242272IPR007087Zinc finger, C2H2
SMARTSM003550.0016242267IPR015880Zinc finger, C2H2-like
Gene3DG3DSA:3.30.160.601.5E-5243268IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE patternPS000280244268IPR007087Zinc finger, C2H2
SMARTSM0035510273299IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280275299IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0005730Cellular Componentnucleolus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0008097Molecular Function5S rRNA binding
GO:0046872Molecular Functionmetal ion binding
GO:0080084Molecular Function5S rDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 350 aa     Download sequence    Send to blast
MEEEKGGKES PKPRDIRRYF CDYCGICRSK KSLITSHILA HHKEKVNEES VDGDGQIDGV  60
KTNTCEECGA TFKKPAYLKQ HMQSHSLEVG RPPEKLHQRP FICSVDDCHA SYRRKDHLTR  120
HLLQHQGKLF RCPIENCSRE FTIQGNMKRH VKEFHNEASA STDVKYEKQY ICSEIGFKLD  180
SVEAFCSEPK CMKYFTNKQC LEAHIRSCHQ HIKCEICGTK QLRKNIKRHL RTHEASGSPE  240
RIKCMFKGCR HSFSTKSNLQ QHVKAVHHEI RPFACGLPGC GMRFAYKHVR DNHEKSGCHT  300
YFLGDFTEAD EQFRSRPRGG RKRKCPTVEM LTRKRVSAPT STESCNVDSD
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1315323RPRGGRKRK
Functional Description ? help Back to Top
Source Description
UniProtEssential protein (PubMed:22353599). Isoform 1 is a transcription activator the binds both 5S rDNA and 5S rRNA and stimulates the transcription of 5S rRNA gene (PubMed:12711688, PubMed:22353599). Isoform 1 regulates 5S rRNA levels during development (PubMed:22353599). {ECO:0000269|PubMed:12711688, ECO:0000269|PubMed:22353599}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00229DAPTransfer from AT1G72050Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006482413.10.0transcription factor IIIA isoform X1
SwissprotQ84MZ41e-134TF3A_ARATH; Transcription factor IIIA
TrEMBLA0A2H5P1N70.0A0A2H5P1N7_CITUN; Uncharacterized protein
STRINGXP_006482413.10.0(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM47142852
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G72050.21e-136transcription factor IIIA