PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_2935_f_3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family C2H2
Protein Properties Length: 454aa    MW: 50634.5 Da    PI: 5.1603
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_2935_f_3genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H215.16.5e-0596118123
                    EEETTTTEEESSHHHHHHHHHHT CS
        zf-C2H2   1 ykCpdCgksFsrksnLkrHirtH 23 
                    ++Cp+Cg+ F++ ++   H  ++
  Neem_2935_f_3  96 FECPICGQAFKTEDEVSIHVESC 118
                    89***************998776 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS501578.78796125IPR007087Zinc finger, C2H2
CDDcd092126.27E-21146241No hitNo description
SuperFamilySSF1435031.12E-17157239IPR018997PUB domain
SMARTSM005809.0E-17159226IPR018997PUB domain
PfamPF094091.6E-16159217IPR018997PUB domain
SuperFamilySSF542362.0E-7306429IPR029071Ubiquitin-related domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0050832Biological Processdefense response to fungus
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 454 aa     Download sequence    Send to blast
MDDMKDKMKA PANPNLARQN IYQTTNSKPK PKANPTSSLN QNSSSLPRKP LGSEQSQSSS  60
VNKPETNREP ANGFDPYESL ITSGKRSQTG YSLNVFECPI CGQAFKTEDE VSIHVESCVN  120
STNNNNLVDN SSGNGTVDDS RSELEACVGT FLSEKPKEGS VEVVLRLLRN VVREPENEKF  180
RRIRMSNPKI REAVGEVAGG VELLEIVGFE LREDGGEMWA TIEVPDKRSI GLISKVIELL  240
EPKKVEEPKK GENLKVEAPA ETEEPVEQKP VDRQIRVFFA VPESVASRIE LPDSFYNLSI  300
GELKREAEMR KKRIDESQLL IPKSYREKQA KAARKRYTKA VICIQFPDGV LLQGIFGPWE  360
QTTALYERKD TVASLGMFVS SALKEPTLQY DLINPASIKR RLVPRFPAPG QKATTLEEED  420
LVPSALIKFR PIETDSAVFT GLSNELLQII EPLE
Functional Description ? help Back to Top
Source Description
UniProtFacilitates the interaction of SYP31 and CDC48A, thereby regulating an CDC48A membrane-associated function (Ref.8). Appears to act as a negative regulator mediating the powdery mildew-plant interaction (PubMed:19176722, PubMed:23301616). {ECO:0000269|PubMed:19176722, ECO:0000269|PubMed:23301616, ECO:0000269|Ref.8}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced in response to powdery mildew and by benzothiadiazole (BTH) treatment. {ECO:0000269|PubMed:19176722}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_006469232.10.0plant UBX domain-containing protein 2
SwissprotQ9ZU931e-167PUX2_ARATH; Plant UBX domain-containing protein 2
TrEMBLA0A067FB390.0A0A067FB39_CITSI; Uncharacterized protein
STRINGXP_006469232.10.0(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM98351618
Publications ? help Back to Top
  1. Suzuki T,Park H,Till EA,Lennarz WJ
    The PUB domain: a putative protein-protein interaction domain implicated in the ubiquitin-proteasome pathway.
    Biochem. Biophys. Res. Commun., 2001. 287(5): p. 1083-7
    [PMID:11587532]
  2. Rancour DM,Park S,Knight SD,Bednarek SY
    Plant UBX domain-containing protein 1, PUX1, regulates the oligomeric structure and activity of arabidopsis CDC48.
    J. Biol. Chem., 2004. 279(52): p. 54264-74
    [PMID:15498773]
  3. Chandran D,Rickert J,Cherk C,Dotson BR,Wildermuth MC
    Host cell ploidy underlying the fungal feeding site is a determinant of powdery mildew growth and reproduction.
    Mol. Plant Microbe Interact., 2013. 26(5): p. 537-45
    [PMID:23301616]