PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_2710_f_3
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family WRKY
Protein Properties Length: 625aa    MW: 67667.4 Da    PI: 6.9444
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_2710_f_3genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY95.14.9e-30275334159
                    ---SS-EEEEEEE--TT-SS-EEEEEE-ST.T---EEEEEE-SSSTTEEEEEEES--SS- CS
           WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsa.gCpvkkkversaedpkvveitYegeHnhe 59 
                    ++Dg++WrKYGqK  kg+++pr+YYrCt a +Cpv+k+v+r+ +d +++++tYeg+Hnh+
  Neem_2710_f_3 275 MNDGCQWRKYGQKIAKGNPCPRAYYRCTVApSCPVRKQVQRCVDDMSILITTYEGTHNHP 334
                    58***************************99****************************7 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.801.6E-31260336IPR003657WRKY domain
SuperFamilySSF1182903.01E-27268336IPR003657WRKY domain
PROSITE profilePS5081128.323270336IPR003657WRKY domain
SMARTSM007742.3E-36275335IPR003657WRKY domain
PfamPF031061.3E-26276334IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 625 aa     Download sequence    Send to blast
MEENRAAAME DIFRRSGRRV TVDVDEEKKA ADSAADPEEI VVKIGKKRLH NENNDTIPSS  60
PEQKHLSSGK QQLDLTNAKG SSLGPNSRPS SSSQKEQDDQ LESARAEMGE VRQENQRLKM  120
YLDRIMKDYQ TLQMQFINIV QQESKKSTDR SNDHEQEIEE PEFVSLSLGR FSSDSRKDDN  180
KNKTSSQGKE DEHDKEGLSL ALDCKFEASK SDANESLPNP SPAHSSEEPK DDTGQTWPPS  240
KVLKTIRSGD DEILQQSQVK KTRVSVRARC DTPTMNDGCQ WRKYGQKIAK GNPCPRAYYR  300
CTVAPSCPVR KQVQRCVDDM SILITTYEGT HNHPLPVSAT AMASTTSAAA SMLLSGASSS  360
SLPGSSAPSA TIPGASNLHG LNFYMSDNSK SKQYYLPNSS LSTSPSHSTI TLDLTTNTPS  420
SSSSHFSTFT SNFPPAPRYS SANLNFSSSE SSSNLLWSNG LLSYSNSSTQ PYIKNQIGSL  480
NLGRQPLENV YQSFMQKNNP TLPEQSLPPD TIAAATKAIT ADPSFQSALA AALKSIIGTG  540
NSGPGGTNQV SGDNFGQKVK WGEQFPAASS HSETVKGSGC GSSYLNKSSA TNSQPGSLIF  600
LPPSLPFSAS KSASASPSDN REHTN
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
2ayd_A2e-19262336174WRKY transcription factor 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator involved in the transcriptional regulation of terpene biosynthesis in glandular trichomes (PubMed:24884371). Binds to the promoter of the linalool synthase TPS5 and promotes TPS5 gene transactivation (PubMed:24884371). In association with WRKY72B, contributes to basal defense against root-knot nematodes (RKNs) and potato aphids, as well as Mi-1-mediated gene-for-gene resistance to these pests (PubMed:20409007). Both WRKY72A and WRKY72B are not required for gene-for-gene resistance mediated by Pto, another tomato R gene (PubMed:20409007). {ECO:0000269|PubMed:20409007, ECO:0000269|PubMed:24884371}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by infection with the root-knot nematode (RKN) Meloidogyne incognita and potato aphids. {ECO:0000269|PubMed:20409007}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007037253.20.0PREDICTED: probable WRKY transcription factor 61
SwissprotA0A3Q7GFB51e-138WK72A_SOLLC; WRKY transcription factor 72A
TrEMBLA0A061G4200.0A0A061G420_THECC; WRKY DNA-binding protein 72, putative
STRINGEOY217540.0(Theobroma cacao)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM29592868
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G15130.11e-67WRKY DNA-binding protein 72
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Spyropoulou EA,Haring MA,Schuurink RC
    RNA sequencing on Solanum lycopersicum trichomes identifies transcription factors that activate terpene synthase promoters.
    BMC Genomics, 2014. 15: p. 402
    [PMID:24884371]