PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_19305_f_1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family C2H2
Protein Properties Length: 176aa    MW: 19985.3 Da    PI: 9.5817
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_19305_f_1genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H215.26.3e-056082123
                    EEETTTTEEESSHHHHHHHHHHT CS
         zf-C2H2  1 ykCpdCgksFsrksnLkrHirtH 23
                    y+C+ C++ F++   L  H+++H
  Neem_19305_f_1 60 YTCSFCKREFRSAQALGGHMNVH 82
                    9********************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF576679.56E-75786No hitNo description
Gene3DG3DSA:3.30.160.609.4E-45884IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PfamPF139121.0E-66083IPR007087Zinc finger, C2H2
PROSITE profilePS5015711.246087IPR007087Zinc finger, C2H2
SMARTSM003550.00386082IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002806282IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 176 aa     Download sequence    Send to blast
MERNSVSNSL KDNKIGSKAI TDSNNNKNSS GNKLKDSWNS NSKSYGEEYL SGFSWPPRSY  60
TCSFCKREFR SAQALGGHMN VHRRDRARLR MSPPRDGQYS FLNLNLNPNF STRPLRPKDS  120
EKKSAKSFSG VEELDYFTGE DGCKISKKAE ILRLDLEIGL ISDSKEDLDL ELRLGY
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1njq_A2e-155582229superman protein
2l1o_A2e-155582229Transcriptional regulator SUPERMAN
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcriptional regulator considered as cadastral protein that acts indirectly to prevent the B class homeotic proteins APETALA3 and perhaps PISTILLATA from acting in the gynoecial whorl. Principal function is to balance cell proliferation in the third and fourth whorls of developing flowers thereby maintaining the boundary between stamens and carpels. May fulfill this role by repressing genes implicated in cell division. Plays equally a role in the determinacy of the floral meristem. Is also required for normal ovule development. {ECO:0000269|PubMed:11006335, ECO:0000269|PubMed:11943180, ECO:0000269|PubMed:12324589, ECO:0000269|PubMed:1352237, ECO:0000269|PubMed:7477325}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Repressed by KRYPTONITE/SUVH4, member of the histone H3-K9 methyltransferase family that contributes with other factors to the CpNpG methylation of the SUP gene resulting in its silencing. The alternative epigenetic states of the SUPERMAN locus have been called Clark Kent alleles. Positively regulated at an early stage of development by LEAFY and by B class homeotic proteins APETALA3 and PISTILLATA. Later expression is maintained by both the B class homeotic proteins and the C class homeotic protein AGAMOUS. These two steps of regulation require the intervention of additional factors. {ECO:0000269|PubMed:11898023}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_024958386.12e-66transcriptional regulator SUPERMAN-like
SwissprotQ388956e-39SUP_ARATH; Transcriptional regulator SUPERMAN
TrEMBLA0A1Q3CMC23e-64A0A1Q3CMC2_CEPFO; Zf-C2H2_6 domain-containing protein
TrEMBLA0A2H5PJS14e-64A0A2H5PJS1_CITUN; Uncharacterized protein
TrEMBLV4S3L84e-64V4S3L8_9ROSI; Uncharacterized protein
STRINGXP_006489609.18e-66(Citrus sinensis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM81092432
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT3G23130.13e-40C2H2 family protein
Publications ? help Back to Top
  1. Breuil-Broyer S, et al.
    Analysis of the Arabidopsis superman allelic series and the interactions with other genes demonstrate developmental robustness and joint specification of male-female boundary, flower meristem termination and carpel compartmentalization.
    Ann. Bot., 2016. 117(5): p. 905-23
    [PMID:27098089]
  2. Prunet N,Yang W,Das P,Meyerowitz EM,Jack TP
    SUPERMAN prevents class B gene expression and promotes stem cell termination in the fourth whorl of Arabidopsis thaliana flowers.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(27): p. 7166-7171
    [PMID:28634297]
  3. Uemura A, et al.
    Regulation of floral meristem activity through the interaction of AGAMOUS, SUPERMAN, and CLAVATA3 in Arabidopsis.
    Plant Reprod, 2018. 31(1): p. 89-105
    [PMID:29218596]
  4. Xu Y, et al.
    SUPERMAN regulates floral whorl boundaries through control of auxin biosynthesis.
    EMBO J., 2019.
    [PMID:29764982]