PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Neem_18886_f_2
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Sapindales; Meliaceae; Azadirachta
Family C2H2
Protein Properties Length: 65aa    MW: 7597 Da    PI: 10.258
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Neem_18886_f_2genomeNGDView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H210.80.00151435323
                    ETTTTEEESSHHHHHHHHHH.T CS
         zf-C2H2  3 CpdCgksFsrksnLkrHirt.H 23
                    C +C++ F +   L++H++  H
  Neem_18886_f_2 14 CYYCDREFDDEKILVQHQKAkH 35
                    99****************9888 PP

2zf-C2H213.60.00023659123
                    EEETTTTEEESSHHHHHHHHHH.T CS
         zf-C2H2  1 ykCpdCgksFsrksnLkrHirt.H 23
                    +kC+ C+k  s+   +  H    H
  Neem_18886_f_2 36 FKCHVCHKKLSTAGGMAIHVLQvH 59
                    89***********99999987655 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5080811.692765IPR003656Zinc finger, BED-type
SuperFamilySSF576674.9E-61161No hitNo description
SMARTSM00355201235IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002801435IPR007087Zinc finger, C2H2
SMARTSM003550.0653659IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002803859IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003677Molecular FunctionDNA binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 65 aa     Download sequence    Send to blast
MGKKKKRVSS KVWCYYCDRE FDDEKILVQH QKAKHFKCHV CHKKLSTAGG MAIHVLQVHK  60
EAVTK
Functional Description ? help Back to Top
Source Description
UniProtSequence-specific DNA binding factor that recognizes the 5'-CCAAATTTTAAGTTT-3' sequence. Recruits the FRI-C complex to the FLC promoter. Required for FRI-mediated FLC activation, but has no effect on the expression of MAF1, MAF2, MAF3, MAF5, UFC and CO. Dispensable for the reactivation of FLC in early embryogenesis, but required to maintain high levels of FLC expression in later embryonic and vegetative development. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694, ECO:0000269|PubMed:19121105, ECO:0000269|PubMed:21282526}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Not regulated by photoperiod or vernalization. {ECO:0000269|PubMed:17079264, ECO:0000269|PubMed:17138694}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_007041015.16e-43PREDICTED: protein SUPPRESSOR OF FRI 4 isoform X2
RefseqXP_011035503.16e-43PREDICTED: protein SUPPRESSOR OF FRI 4-like isoform X4
RefseqXP_011035504.16e-43PREDICTED: protein SUPPRESSOR OF FRI 4-like isoform X5
RefseqXP_021300281.16e-43protein SUPPRESSOR OF FRI 4
RefseqXP_021607215.16e-43protein SUPPRESSOR OF FRI 4 isoform X1
RefseqXP_021607216.16e-43protein SUPPRESSOR OF FRI 4 isoform X2
RefseqXP_021655872.14e-43protein SUPPRESSOR OF FRI 4-like isoform X2
RefseqXP_022725418.17e-43protein SUPPRESSOR OF FRI 4-like isoform X4
RefseqXP_022725419.16e-43protein SUPPRESSOR OF FRI 4-like isoform X5
RefseqXP_022725420.15e-43protein SUPPRESSOR OF FRI 4-like isoform X6
RefseqXP_022725421.15e-43protein SUPPRESSOR OF FRI 4-like isoform X7
RefseqXP_022762592.16e-43protein SUPPRESSOR OF FRI 4 isoform X1
RefseqXP_022762593.16e-43protein SUPPRESSOR OF FRI 4 isoform X2
RefseqXP_022762594.15e-43protein SUPPRESSOR OF FRI 4 isoform X3
RefseqXP_024020147.16e-43protein SUPPRESSOR OF FRI 4 isoform X1
RefseqXP_024020148.16e-43protein SUPPRESSOR OF FRI 4 isoform X2
RefseqXP_024020149.15e-43protein SUPPRESSOR OF FRI 4 isoform X3
RefseqXP_024020150.15e-43protein SUPPRESSOR OF FRI 4 isoform X4
RefseqXP_024444354.16e-43protein SUPPRESSOR OF FRI 4 isoform X2
RefseqXP_027340592.15e-43protein SUPPRESSOR OF FRI 4 isoform X3
SwissprotQ9C5G03e-40SUF4_ARATH; Protein SUPPRESSOR OF FRI 4
TrEMBLA0A061DWR61e-41A0A061DWR6_THECC; Zinc finger family protein isoform 3 (Fragment)
STRINGEOX968454e-42(Theobroma cacao)
STRINGPOPTR_0001s16080.12e-42(Populus trichocarpa)
STRINGGLYMA05G34280.13e-42(Glycine max)
STRINGGLYMA08G05390.15e-42(Glycine max)
STRINGXP_002528158.12e-42(Ricinus communis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM76951720
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G30970.11e-42C2H2 family protein
Publications ? help Back to Top
  1. Ding L,Kim SY,Michaels SD
    FLOWERING LOCUS C EXPRESSOR family proteins regulate FLOWERING LOCUS C expression in both winter-annual and rapid-cycling Arabidopsis.
    Plant Physiol., 2013. 163(1): p. 243-52
    [PMID:23899645]
  2. Resentini F, et al.
    SUPPRESSOR OF FRIGIDA (SUF4) Supports Gamete Fusion via Regulating Arabidopsis EC1 Gene Expression.
    Plant Physiol., 2017. 173(1): p. 155-166
    [PMID:27920160]