PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AHYPO_016574-RA
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Amaranthaceae; Amaranthus
Family bHLH
Protein Properties Length: 500aa    MW: 55469.6 Da    PI: 6.967
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AHYPO_016574-RAgenomeBYUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH40.35.9e-13353400355
                      HHHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
              HLH   3 rahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                      r+h  +Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI++Lq
  AHYPO_016574-RA 353 RSHVLAERQRREKLNQRFYALRAVVPNiS------KMDKASLLLDAISYINDLQ 400
                      6899***********************66......******************9 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142153.6E-4648227IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088817.098350399IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474591.83E-18352420IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000833.30E-14353404No hitNo description
PfamPF000101.5E-10353400IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.9E-19354419IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003531.1E-15356405IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 500 aa     Download sequence    Send to blast
MGHNHMLTEE EKGLVEAVVG KDAYNFLMST ASDDSLSEFN PPGDILNLQN GLCQIVDGSS  60
WNYAIFWQIA SSKNGRAVLI WGDGHCRDPR TMVLDGGNGK LGTSKDEAKK RVLEKLHACF  120
GGSEEDNFAS TLDKVSDIEM LYLTSMYYWF RLDSSLGPAK SFVSGRSIWV SDVRSCLDHY  180
QSRAHLAKSA MFQTVVFVPV KTGVLELGSV RTVMEEPTLV QMVKTVFGES HSTQDKVSSK  240
VFGRDLSLST SRPRSMNISF APKKEDDASF SAESGVGGSD MGAKRVYGSS SNGKHSEPSD  300
KKLFSEINFG GSNPDNDFPG LDEASEELLL HAAELRARKR PTRRPVIGRE EARSHVLAER  360
QRREKLNQRF YALRAVVPNI SKMDKASLLL DAISYINDLQ TKISKLEAEK EKANSKQDQF  420
PIPEIDFHTR KDDALVHVTF PLDVHPVSKV VRTLREHQHV ALEANISTTE DKMIHTFTIR  480
AQAGEAEKLK EKVEAALSK*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A3e-25347410164Transcription factor MYC2
5gnj_B3e-25347410164Transcription factor MYC2
5gnj_E3e-25347410164Transcription factor MYC2
5gnj_F3e-25347410164Transcription factor MYC2
5gnj_G3e-25347410164Transcription factor MYC2
5gnj_I3e-25347410164Transcription factor MYC2
5gnj_M3e-25347410164Transcription factor MYC2
5gnj_N3e-25347410164Transcription factor MYC2
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021770217.10.0transcription factor bHLH3-like
SwissprotA0A3Q7H2161e-164MTB3_SOLLC; Transcription factor MTB3
TrEMBLA0A0K9Q7E40.0A0A0K9Q7E4_SPIOL; Uncharacterized protein
STRINGXP_010679204.10.0(Beta vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G16430.11e-140bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]