PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AHYPO_013589-RA
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; Caryophyllales; Amaranthaceae; Amaranthus
Family bHLH
Protein Properties Length: 648aa    MW: 71439.4 Da    PI: 7.612
Description bHLH family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AHYPO_013589-RAgenomeBYUView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1HLH41.72e-13476522455
                      HHHHHHHHHHHHHHHHHHHHHCTSCC.C...TTS-STCHHHHHHHHHHHHHHH CS
              HLH   4 ahnerErrRRdriNsafeeLrellPk.askapskKlsKaeiLekAveYIksLq 55 
                      +h e+Er+RR+++N++f  Lr ++P+ +      K++Ka+ L  A+ YI +Lq
  AHYPO_013589-RA 476 NHVEAERQRREKLNQRFCALRAVVPNiS------KMDKASLLGDAISYITELQ 522
                      799***********************66......*****************99 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF142151.7E-4948235IPR025610Transcription factor MYC/MYB N-terminal
PROSITE profilePS5088816.761472521IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SuperFamilySSF474593.27E-18475535IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
CDDcd000832.74E-14475526No hitNo description
PfamPF000106.9E-11476522IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene3DG3DSA:4.10.280.101.2E-17476537IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
SMARTSM003533.0E-15478527IPR011598Myc-type, basic helix-loop-helix (bHLH) domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0044212Molecular Functiontranscription regulatory region DNA binding
GO:0046983Molecular Functionprotein dimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 648 aa     Download sequence    Send to blast
MGGGLVWNEE DKAMIASILG TKAFEYLISS PFTAETSLVS IENNENIQIK LCDLVERPNA  60
SNFSWNYGFF WQVSRAKSGE MVLSWGDGYC REPREGEESE ATRLLNFRLE DEAQQKIRKR  120
VLQKLNTLFG GSDDDNLACR LDRVTDMEMF FLVSMYFSFP RGEGGPGKCF ASGKHVWESD  180
LLRSKLDYCV RSFLAKSAGI QTVILIPTEF GVVELGSVRA IKEHQDVLKA LKFAFTSPTV  240
IRPKPTPSLP VVIHKIEDND PVPLPLTIPA SGSVPRPALA PAHAPIASTV AARAPVTSTL  300
PTPAPAPGRG VDNATKIFGQ NLNTAVRPPF REKLAVKRME DRNWDAYSNG NKLSFAGQSL  360
RNGVHGTNWS SIPGIKHATT TEIYNPQNTT RLQDYVNGIR TEYRLNQFQQ QKPAQMEIDF  420
SGATSRPSVI SQPGSAESEH SDAEVSGRDD RAGPSDDRRP RKRGRKPANG REEPLNHVEA  480
ERQRREKLNQ RFCALRAVVP NISKMDKASL LGDAISYITE LQKKLKDMET EREKHNNASK  540
DKTSSTEANS GADSQTQLSD VEVQAVHDEV VVKVSCALDS HPVARVIRAF KESEINVVDS  600
KLAAGTDTVF HTFVIRSDDS DQLTKEKLLA AFTHESKSLQ GPSSTGG*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5gnj_A4e-27470532264Transcription factor MYC2
5gnj_B4e-27470532264Transcription factor MYC2
5gnj_E4e-27470532264Transcription factor MYC2
5gnj_F4e-27470532264Transcription factor MYC2
5gnj_G4e-27470532264Transcription factor MYC2
5gnj_I4e-27470532264Transcription factor MYC2
5gnj_M4e-27470532264Transcription factor MYC2
5gnj_N4e-27470532264Transcription factor MYC2
Search in ModeBase
Nucleic Localization Signal ? help Back to Top
NLS
No. Start End Sequence
1457465RRPRKRGRK
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor that negatively regulates jasmonate (JA) signaling (PubMed:30610166). Negatively regulates JA-dependent response to wounding, JA-induced expression of defense genes, JA-dependent responses against herbivorous insects, and JA-dependent resistance against Botrytis cinerea infection (PubMed:30610166). Plays a positive role in resistance against the bacterial pathogen Pseudomonas syringae pv tomato DC3000 (PubMed:30610166). {ECO:0000269|PubMed:30610166}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00100PBMTransfer from AT1G01260Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by wounding, feeding with herbivorous insects, infection with the fungal pathogen Botrytis cinerea and infection with the bacterial pathogen Pseudomonas syringae pv tomato DC3000. {ECO:0000269|PubMed:30610166}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_010696336.10.0PREDICTED: transcription factor bHLH13
SwissprotA0A3Q7ELQ20.0MTB1_SOLLC; Transcription factor MTB1
TrEMBLA0A0K9QUK20.0A0A0K9QUK2_SPIOL; Uncharacterized protein
STRINGXP_010696336.10.0(Beta vulgaris)
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G01260.31e-170bHLH family protein
Publications ? help Back to Top
  1. Tomato Genome Consortium
    The tomato genome sequence provides insights into fleshy fruit evolution.
    Nature, 2012. 485(7400): p. 635-41
    [PMID:22660326]
  2. Sun H,Fan HJ,Ling HQ
    Genome-wide identification and characterization of the bHLH gene family in tomato.
    BMC Genomics, 2015. 16: p. 9
    [PMID:25612924]
  3. Liu Y, et al.
    MYC2 Regulates the Termination of Jasmonate Signaling via an Autoregulatory Negative Feedback Loop.
    Plant Cell, 2019. 31(1): p. 106-127
    [PMID:30610166]