PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Aradu.M33V1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; Dalbergieae; Arachis
Family C2H2
Protein Properties Length: 363aa    MW: 41490 Da    PI: 7.0283
Description C2H2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Aradu.M33V1genomeNCGR_PGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1zf-C2H212.40.000497395323
                 ET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2  3 Cp..dCgksFsrksnLkrHirtH 23
                 C+   Cgk+F +   L++H   H
  Aradu.M33V1 73 CSyeGCGKTFIDAGALRKHSHIH 95
                 77779**************7766 PP

2zf-C2H215.93.8e-05100124123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  ++C+   Cgk F ++s LkrH   H
  Aradu.M33V1 100 FVCHyeGCGKKFLDSSKLKRHFLIH 124
                  89*******************8877 PP

3zf-C2H221.75.1e-07130154123
                  EEET..TTTEEESSHHHHHHHHHHT CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirtH 23 
                  ++Cp   Cgk Fs   nL++H++tH
  Aradu.M33V1 130 FVCPheGCGKAFSLDFNLRSHMKTH 154
                  89**********************9 PP

4zf-C2H218.17.1e-06160185123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  + Cp  dCgk++ + + Lk+Hi + H
  Aradu.M33V1 160 HICPypDCGKRYAHEYKLKNHIASqH 185
                  679999****************9988 PP

5zf-C2H2130.0003223248123
                  EEET..TTTEEESSHHHHHHHHHH.T CS
      zf-C2H2   1 ykCp..dCgksFsrksnLkrHirt.H 23 
                  y Cp   C k + + + Lk H+++ H
  Aradu.M33V1 223 YACPyeGCEKAYIHEYKLKLHLKReH 248
                  89*********************999 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:3.30.160.608.9E-146697IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015710.74171100IPR007087Zinc finger, C2H2
SMARTSM003550.00327195IPR015880Zinc finger, C2H2-like
PROSITE patternPS0002807395IPR007087Zinc finger, C2H2
SuperFamilySSF576674.27E-874124No hitNo description
Gene3DG3DSA:3.30.160.603.4E-1498120IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015713.734100129IPR007087Zinc finger, C2H2
SMARTSM003550.0043100124IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280102124IPR007087Zinc finger, C2H2
SuperFamilySSF576675.5E-14111163No hitNo description
Gene3DG3DSA:3.30.160.605.4E-20121156IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS5015712.695130159IPR007087Zinc finger, C2H2
SMARTSM003553.1E-4130154IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280132154IPR007087Zinc finger, C2H2
Gene3DG3DSA:3.30.160.601.0E-7157181IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501578.746160190IPR007087Zinc finger, C2H2
SMARTSM003550.003160185IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280162185IPR007087Zinc finger, C2H2
SuperFamilySSF576671.88E-5218246No hitNo description
Gene3DG3DSA:3.30.160.606.2E-9219245IPR013087Zinc finger C2H2-type/integrase DNA-binding domain
PROSITE profilePS501579.93223253IPR007087Zinc finger, C2H2
SMARTSM003550.012223248IPR015880Zinc finger, C2H2-like
PROSITE patternPS000280225248IPR007087Zinc finger, C2H2
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0003676Molecular Functionnucleic acid binding
GO:0046872Molecular Functionmetal ion binding
Sequence ? help Back to Top
Protein Sequence    Length: 363 aa     Download sequence    Send to blast
METQFNHNLF ERRPFLKSKA PAVKWGSSRR CSYWREVHAP KMEDSLKALK EKEKEPSAPE  60
PEPEPTTEVL FLCSYEGCGK TFIDAGALRK HSHIHGERQF VCHYEGCGKK FLDSSKLKRH  120
FLIHTGERDF VCPHEGCGKA FSLDFNLRSH MKTHSQENYH ICPYPDCGKR YAHEYKLKNH  180
IASQHEKNAS VDLTKYTPPS EKPAKPTKPA SGTYGSASSD RPYACPYEGC EKAYIHEYKL  240
KLHLKREHPG HDENAVRAQA NADNEMDEAS EQDAYGRKRS NGKSQKQSRP KPSLKLPPAK  300
IAQRKGSAPT PAASNAIKKS WPVKEEVYDE DSEETEEDRD NVEDGWRYAA NNDDDDEETE  360
YED
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ubd_C7e-34731848119PROTEIN (YY1 ZINC FINGER DOMAIN)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtDual-function transcription factor with both repression and activation activities. Binds to 5'-CCATATT-3' motif in target gene promoters (e.g. ABR1) (PubMed:26961720). Binds also to G-rich DNA motif 5'-GGGGGCAGTGG-3' (PubMed:22508367). Regulates the expression of genes involved in diverse cellular pathways, including glucose metabolism, photosynthesis, phototropism and stress response (e.g. salt, drought and osmotic stress) (PubMed:22508367, PubMed:26961720). Regulates plant immunity, especially during necrotrophic fungal infection (e.g. B.cinerea) (PubMed:24451981). Binds to ABR1 promoter and promotes its expression, thus negatively regulating the abscisic acid (ABA) signaling pathway. Represses ABA- and salt-responsive genes expression (PubMed:26961720). {ECO:0000269|PubMed:22508367, ECO:0000269|PubMed:24451981, ECO:0000269|PubMed:26961720}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapAradu.M33V1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in an ABI1- and ABI4-dependent manner. Stimulated by stress conditions including high salt, osmotic stress (e.g. mannitol) and dehydration. May be induced by ABI4 but repressed by ABR1. Repressed by darkness but induced by light. {ECO:0000269|PubMed:26961720}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_015958808.10.0uncharacterized zinc finger protein At4g06634
SwissprotQ2V3L31e-138YY1_ARATH; Zinc finger transcription factor YY1
TrEMBLA0A445DKB10.0A0A445DKB1_ARAHY; Uncharacterized protein
STRINGXP_004485467.10.0(Cicer arietinum)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
FabidsOGEF56493354
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT4G06634.11e-131C2H2 family protein
Publications ? help Back to Top
  1. Kumekawa N,Hosouchi T,Tsuruoka H,Kotani H
    The size and sequence organization of the centromeric region of Arabidopsis thaliana chromosome 4.
    DNA Res., 2001. 8(6): p. 285-90
    [PMID:11853315]
  2. Li T,Wu XY,Li H,Song JH,Liu JY
    A Dual-Function Transcription Factor, AtYY1, Is a Novel Negative Regulator of the Arabidopsis ABA Response Network.
    Mol Plant, 2016. 9(5): p. 650-661
    [PMID:26961720]
  3. Wu XY,Li T
    A Casein Kinase II Phosphorylation Site in AtYY1 Affects Its Activity, Stability, and Function in the ABA Response.
    Front Plant Sci, 2017. 8: p. 323
    [PMID:28348572]