PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID Achn198481
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; Ericales; Actinidiaceae; Actinidia
Family ERF
Protein Properties Length: 490aa    MW: 54669.7 Da    PI: 4.6616
Description ERF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
Achn198481genomeIKGCView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP259.48.6e-19109158255
         AP2   2 gykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaeeAakaaiaarkkleg 55 
                 +y+G+r+++ +g+W+AeIrdp++     r++lg+f taeeAa a++a ++k++g
  Achn198481 109 QYRGIRQRP-WGKWAAEIRDPRK---GVRVWLGTFNTAEEAAIAYDAEARKIRG 158
                 69*******.**********954...4*************************98 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PROSITE profilePS5103223.696109166IPR001471AP2/ERF domain
SuperFamilySSF541714.25E-22109168IPR016177DNA-binding domain
SMARTSM003807.4E-38109172IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.109.2E-32109168IPR001471AP2/ERF domain
CDDcd000182.05E-32109167No hitNo description
PRINTSPR003675.7E-11110121IPR001471AP2/ERF domain
PfamPF008475.6E-11110158IPR001471AP2/ERF domain
PRINTSPR003675.7E-11132148IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 490 aa     Download sequence    Send to blast
MCGGAIISDF IAPTRNRRLI ENLLWPSDVK KNHSNYHSKP LRSEIVDLDD DFEADFQDFK  60
DDTDAEDNDF KSFVFSASKS GVSDGSRSTK SVELNGQTEK TAKRKRKNQY RGIRQRPWGK  120
WAAEIRDPRK GVRVWLGTFN TAEEAAIAYD AEARKIRGRK AKVNFPDEAP PNAAKRAIKA  180
NTQKVLAKES INSVQPNLNQ NFNFPNNPEN DCYSMNFEEE KPLTGQFGYT EAYPVPGEVG  240
HKSSTPSAGA IPLYFNSDQG SNSFDCSDFE WGEYNTKTPD ISSVLSATIE CDEAQFVDNA  300
NPTEKLKTKL EDVGPVQENT VEKLSEELSA FESQMKFFQI PYLEANWDAS VDTFLNGDAT  360
QDGGSSMNLW TFDDFPSMMG GVFAVMDTVD KPVNLLSPLD GVLINLALGG YQDDIRRHSV  420
ANEHNEKCIT SFTIGHVRWQ KWVWMNSSAF RLVQEADSLG DWFCCNGLCC RSITKFGDSL  480
QDLAVGLAT*
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1gcc_A9e-22109166260ETHYLENE RESPONSIVE ELEMENT BINDING FACTOR 1
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription factor involved in the activation of hypoxic gene expression and in ethylene response. Partially redundant with RAP2-2. Acts as a downstream regulator in the ethylene signaling pathway. {ECO:0000269|PubMed:22020282, ECO:0000269|PubMed:22530619}.
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Up-regulated by hypoxia but not by ethylene. {ECO:0000269|PubMed:22020282}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankGQ8698560.0GQ869856.1 Actinidia deliciosa ethylene response factor 5 (ERF5) mRNA, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_028064263.10.0ethylene-responsive transcription factor RAP2-12-like
SwissprotQ9SSA83e-78RA212_ARATH; Ethylene-responsive transcription factor RAP2-12
TrEMBLD8VD320.0D8VD32_ACTDE; Ethylene response factor 5
STRINGXP_009775920.11e-164(Nicotiana sylvestris)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA14462466
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G53910.23e-67related to AP2 12
Publications ? help Back to Top
  1. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  2. Kosmacz M, et al.
    The stability and nuclear localization of the transcription factor RAP2.12 are dynamically regulated by oxygen concentration.
    Plant Cell Environ., 2015. 38(6): p. 1094-103
    [PMID:25438831]
  3. Bui LT,Giuntoli B,Kosmacz M,Parlanti S,Licausi F
    Constitutively expressed ERF-VII transcription factors redundantly activate the core anaerobic response in Arabidopsis thaliana.
    Plant Sci., 2015. 236: p. 37-43
    [PMID:26025519]
  4. Gasch P, et al.
    Redundant ERF-VII Transcription Factors Bind to an Evolutionarily Conserved cis-Motif to Regulate Hypoxia-Responsive Gene Expression in Arabidopsis.
    Plant Cell, 2016. 28(1): p. 160-80
    [PMID:26668304]
  5. Gonzali S, et al.
    Universal stress protein HRU1 mediates ROS homeostasis under anoxia.
    Nat Plants, 2015. 1: p. 15151
    [PMID:27251529]
  6. Paul MV, et al.
    Oxygen Sensing via the Ethylene Response Transcription Factor RAP2.12 Affects Plant Metabolism and Performance under Both Normoxia and Hypoxia.
    Plant Physiol., 2016. 172(1): p. 141-53
    [PMID:27372243]
  7. Shahzad Z, et al.
    A Potassium-Dependent Oxygen Sensing Pathway Regulates Plant Root Hydraulics.
    Cell, 2016. 167(1): p. 87-98.e14
    [PMID:27641502]
  8. Yao Y, et al.
    ETHYLENE RESPONSE FACTOR 74 (ERF74) plays an essential role in controlling a respiratory burst oxidase homolog D (RbohD)-dependent mechanism in response to different stresses in Arabidopsis.
    New Phytol., 2017. 213(4): p. 1667-1681
    [PMID:28164334]
  9. Giuntoli B,Licausi F,van Veen H,Perata P
    Functional Balancing of the Hypoxia Regulators RAP2.12 and HRA1 Takes Place in vivo in Arabidopsis thaliana Plants.
    Front Plant Sci, 2017. 8: p. 591
    [PMID:28487707]
  10. Yao Y,Chen X,Wu AM
    ERF-VII members exhibit synergistic and separate roles in Arabidopsis.
    Plant Signal Behav, 2017. 12(6): p. e1329073
    [PMID:28537474]
  11. Eysholdt-Derzsó E,Sauter M
    Root Bending Is Antagonistically Affected by Hypoxia and ERF-Mediated Transcription via Auxin Signaling.
    Plant Physiol., 2017. 175(1): p. 412-423
    [PMID:28698356]
  12. Giuntoli B, et al.
    Age-dependent regulation of ERF-VII transcription factor activity in Arabidopsis thaliana.
    Plant Cell Environ., 2017. 40(10): p. 2333-2346
    [PMID:28741696]