PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID AA54G00421
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Aethionemeae; Aethionema
Family TCP
Protein Properties Length: 368aa    MW: 40561.2 Da    PI: 9.6383
Description TCP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
AA54G00421genomeVEGIView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1TCP120.32.3e-37441882136
         TCP   2 agkkdrhskihTkvggRdRRvRlsaecaarfFdLqdeLGfdkdsktieWLlqqakpaikeltgt.....ssssasec...eaesssssasnsssg.... 88 
                  g+kdrhsk+ T++g+RdRR+Rls+++a++f+dLqd+LG+d++sk++eWL+++a  +i +l++      +++++++    + ++          +    
  AA54G00421  44 SGGKDRHSKVLTSKGLRDRRIRLSVSTAIQFYDLQDRLGLDQPSKAVEWLINAASDSISDLPSInpnfsETNHNNNGgfgDFNEI---------Rdfnq 133
                 689***********************************************************99544431111111133322222.........23333 PP

         TCP  89 ......kaaksaakskksqksaasalnlak.esrakarararertrekmriknkl 136
                       +++  + +s+ s++s+a+ l+l++ e r kar+rarert++++ +++++
  AA54G00421 134 nqtlslSKSGGSSTSETSKTSSAAGLSLSRtEIRGKARERARERTAKEKEKDHQN 188
                 44455545555557777888888899999999*************9999888665 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF036344.7E-3745183IPR005333Transcription factor, TCP
PROSITE profilePS5136930.36946104IPR017887Transcription factor TCP subgroup
PROSITE profilePS513709.766164182IPR017888CYC/TB1, R domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0008285Biological Processnegative regulation of cell proliferation
GO:0009965Biological Processleaf morphogenesis
GO:0030154Biological Processcell differentiation
GO:0045962Biological Processpositive regulation of development, heterochronic
Sequence ? help Back to Top
Protein Sequence    Length: 368 aa     Download sequence    Send to blast
MEEVDEIEPS RKLQKLSNIT EMTPNSRIRD WTPSSRIIRV SRASGGKDRH SKVLTSKGLR  60
DRRIRLSVST AIQFYDLQDR LGLDQPSKAV EWLINAASDS ISDLPSINPN FSETNHNNNG  120
GFGDFNEIRD FNQNQTLSLS KSGGSSTSET SKTSSAAGLS LSRTEIRGKA RERARERTAK  180
EKEKDHQNTI ESSFTQLLTG GFHQTGSNGS TQTGLTRQWN GSGSGSGSGT DYFNPVLPHI  240
PQFTISNDQN RQQMNQEFSF VPDLTTPVTD YNTLNFGISS SSCCSSRSAI NGGYNSRGTL  300
QSNTTSFLFN NNIHQRSSSS SSSSSSPSFF MAAPSSLEEH SQNLQTGFDG RLFMYGNRSS  360
ENKGKERR
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
5zkt_A1e-2151105155Putative transcription factor PCF6
5zkt_B1e-2151105155Putative transcription factor PCF6
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtPlays a pivotal role in the control of morphogenesis of shoot organs by negatively regulating the expression of boundary-specific genes such as CUC genes, probably through the induction of miRNA (e.g. miR164). In association with ABAP1, exerts a negative role in cell proliferation in leaves, possibly by inhibiting mitotic DNA replication. Participates in ovule develpment (PubMed:25378179). {ECO:0000269|PubMed:17307931, ECO:0000269|PubMed:18818695, ECO:0000269|PubMed:25378179}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00169DAPTransfer from AT1G30210Download
Motif logo
Cis-element ? help Back to Top
SourceLink
PlantRegMapAA54G00421
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieveRetrieve
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqNP_564351.11e-103TEOSINTE BRANCHED 1, cycloidea, and PCF family 24
RefseqNP_849730.11e-103TEOSINTE BRANCHED 1, cycloidea, and PCF family 24
SwissprotQ9C7581e-104TCP24_ARATH; Transcription factor TCP24
TrEMBLD7KES01e-102D7KES0_ARALL; Uncharacterized protein
STRINGfgenesh2_kg.1__3195__AT1G30210.21e-102(Arabidopsis lyrata)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM138401726
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT1G30210.21e-78TCP family protein
Publications ? help Back to Top
  1. Wang H,Mao Y,Yang J,He Y
    TCP24 modulates secondary cell wall thickening and anther endothecium development.
    Front Plant Sci, 2015. 6: p. 436
    [PMID:26157444]
  2. Zhu P, et al.
    Arabidopsis small nucleolar RNA monitors the efficient pre-rRNA processing during ribosome biogenesis.
    Proc. Natl. Acad. Sci. U.S.A., 2016. 113(42): p. 11967-11972
    [PMID:27708161]