PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID KFK33777.1
Organism
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Arabideae; Arabis
Family NAC
Protein Properties Length: 309aa    MW: 35147.1 Da    PI: 6.5263
Description NAC family protein
Gene Model
Gene Model ID Type Source Coding Sequence
KFK33777.1genomeMPIPBRView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1NAM1806.1e-56261521129
         NAM   1 lppGfrFhPtdeelvveyLkkkvegkkleleevikevdiykvePwdLpkkvkaeekewyfFskrdkkyatgkrknratksgyWkatgkdkevlskkgel 99 
                 lppGfrFhPtdeel+++yLk+kv ++ ++   +i evd++kvePwdLp k+k +ekewyfF+ rd+ky+tg r+nratk+gyWkatgkdke+++ +++l
  KFK33777.1  26 LPPGFRFHPTDEELITHYLKPKVLNTFFSS-LAIGEVDLNKVEPWDLPWKAKLGEKEWYFFCVRDRKYPTGLRTNRATKAGYWKATGKDKEIFK-GKSL 122
                 79************************9988.67***************888999****************************************.999* PP

         NAM 100 vglkktLvfykgrapkgektdWvmheyrle 129
                 vg+kktLvfykgrapkg+kt+Wvmheyrle
  KFK33777.1 123 VGMKKTLVFYKGRAPKGVKTNWVMHEYRLE 152
                 ****************************85 PP

Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF1019412.35E-6221176IPR003441NAC domain
PROSITE profilePS5100558.4526176IPR003441NAC domain
PfamPF023652.4E-3027151IPR003441NAC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0005634Cellular Componentnucleus
GO:0003677Molecular FunctionDNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 309 aa     Download sequence    Send to blast
MVNEVSRIDE IVKGEEVQDS YQIDSLPPGF RFHPTDEELI THYLKPKVLN TFFSSLAIGE  60
VDLNKVEPWD LPWKAKLGEK EWYFFCVRDR KYPTGLRTNR ATKAGYWKAT GKDKEIFKGK  120
SLVGMKKTLV FYKGRAPKGV KTNWVMHEYR LEGEYDIDDL PKTDKNEWVI SRVFQKRADG  180
KKMHISGLMM IGSGVNQFKP VGLPPLMDSS QDVKSKGGGE EESLAGSLSN MTCFSDQITE  240
DKNLLSDSKE ATHLMPNIGS LLYSDPLFLQ DNFSGLKMLL NGQETQFKHN LQISGYVAGS  300
VEDDCFWNF
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1ut4_A4e-532518216171NO APICAL MERISTEM PROTEIN
1ut4_B4e-532518216171NO APICAL MERISTEM PROTEIN
1ut7_A4e-532518216171NO APICAL MERISTEM PROTEIN
1ut7_B4e-532518216171NO APICAL MERISTEM PROTEIN
3swm_A5e-532518219174NAC domain-containing protein 19
3swm_B5e-532518219174NAC domain-containing protein 19
3swm_C5e-532518219174NAC domain-containing protein 19
3swm_D5e-532518219174NAC domain-containing protein 19
3swp_A5e-532518219174NAC domain-containing protein 19
3swp_B5e-532518219174NAC domain-containing protein 19
3swp_C5e-532518219174NAC domain-containing protein 19
3swp_D5e-532518219174NAC domain-containing protein 19
4dul_A4e-532518216171NAC domain-containing protein 19
4dul_B4e-532518216171NAC domain-containing protein 19
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that binds to DNA in promoters of target genes on a specific bipartite motif 5'-[ACG][CA]GT[AG](5-6n)[CT]AC[AG]-3' (PubMed:23340744). Promotes lateral root development (PubMed:16359384). Triggers the expression of senescence-associated genes during age-, salt- and dark-induced senescence through a regulatory network that may involve cross-talk with salt- and H(2)O(2)-dependent signaling pathways (PubMed:9351240, PubMed:15295076, PubMed:20113437, PubMed:21303842). Regulates also genes during seed germination (PubMed:20113437). Regulates positively aging-induced cell death (PubMed:19229035). Involved in age-related resistance (ARR) against Pseudomonas syringae pv. tomato and Hyaloperonospora arabidopsidis (PubMed:19694953). Antagonizes GLK1 and GLK2 transcriptional activity, shifting the balance from chloroplast maintenance towards deterioration during leaf senescence (PubMed:23459204). Promotes the expression of senescence-associated genes, including ENDO1/BFN1, SWEET15/SAG29 and SINA1/At3g13672, during senescence onset (PubMed:23340744). {ECO:0000269|PubMed:15295076, ECO:0000269|PubMed:16359384, ECO:0000269|PubMed:19229035, ECO:0000269|PubMed:19694953, ECO:0000269|PubMed:20113437, ECO:0000269|PubMed:21303842, ECO:0000269|PubMed:23340744, ECO:0000269|PubMed:23459204, ECO:0000269|PubMed:9351240}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapKFK33777.1
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: High levels during senescence (e.g. age-, salt- and dark-related) (PubMed:19229035, PubMed:20113437, PubMed:21511905, PubMed:22930749). By salt stress in an ethylene- and auxin-dependent manner (PubMed:16359384, PubMed:19608714, PubMed:20113437, PubMed:20404534). Induced by H(2)O(2) (PubMed:20404534). Accumulates in response to abscisic acid (ABA), ethylene (ACC) and auxin (NAA) (PubMed:16359384, PubMed:19608714). Repressed by high auxin (IAA) levels (PubMed:21511905). Age-related resistance (ARR)-associated accumulation (PubMed:19694953). Repressed by miR164 (PubMed:19229035). {ECO:0000269|PubMed:16359384, ECO:0000269|PubMed:19229035, ECO:0000269|PubMed:19608714, ECO:0000269|PubMed:19694953, ECO:0000269|PubMed:20113437, ECO:0000269|PubMed:20404534, ECO:0000269|PubMed:21511905, ECO:0000269|PubMed:22930749}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAY0626381e-159AY062638.1 Arabidopsis thaliana Unknown protein (MRI12.1) mRNA, complete cds.
GenBankBT0087161e-159BT008716.1 Arabidopsis thaliana At3g29035 gene, complete cds.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_018454635.11e-164PREDICTED: NAC domain-containing protein 59-like
SwissprotQ9FKA01e-146NAC92_ARATH; NAC domain-containing protein 92
TrEMBLA0A087GV750.0A0A087GV75_ARAAL; Uncharacterized protein
STRINGA0A087GV750.0(Arabis alpina)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM40028174
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT5G39610.11e-144NAC domain containing protein 6
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Manacorda CA, et al.
    Salicylic acid determines differential senescence produced by two Turnip mosaic virus strains involving reactive oxygen species and early transcriptomic changes.
    Mol. Plant Microbe Interact., 2013. 26(12): p. 1486-98
    [PMID:23945002]
  3. Khan M,Rozhon W,Poppenberger B
    The role of hormones in the aging of plants - a mini-review.
    Gerontology, 2014. 60(1): p. 49-55
    [PMID:24135638]
  4. Ding Y, et al.
    Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.
    BMC Plant Biol., 2013. 13: p. 229
    [PMID:24377444]
  5. Bohner A,Kojima S,Hajirezaei M,Melzer M,von Wirén N
    Urea retranslocation from senescing Arabidopsis leaves is promoted by DUR3-mediated urea retrieval from leaf apoplast.
    Plant J., 2015. 81(3): p. 377-87
    [PMID:25440717]
  6. Sakuraba Y,Bülbül S,Piao W,Choi G,Paek NC
    Arabidopsis EARLY FLOWERING3 increases salt tolerance by suppressing salt stress response pathways.
    Plant J., 2017. 92(6): p. 1106-1120
    [PMID:29032592]
  7. Kim H, et al.
    Circadian control of ORE1 by PRR9 positively regulates leaf senescence in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2018. 115(33): p. 8448-8453
    [PMID:30065116]