PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Rosa multiflora
E2F/DP Family
Species TF ID Description
Rmu_co8386149.1_g000001.1E2F/DP family protein
Rmu_sc0001754.1_g000006.1E2F/DP family protein
Rmu_sc0003154.1_g000003.1E2F/DP family protein
Rmu_sc0003441.1_g000098.1E2F/DP family protein
Rmu_sc0003547.1_g000004.1E2F/DP family protein
Rmu_sc0004156.1_g000008.1E2F/DP family protein
Rmu_sc0007546.1_g000012.1E2F/DP family protein
Rmu_sc0009210.1_g000003.1E2F/DP family protein
Rmu_sc0009897.1_g000004.1E2F/DP family protein
Rmu_sc0016637.1_g000006.1E2F/DP family protein
Rmu_sc0018174.1_g000003.1E2F/DP family protein
Rmu_sc0026100.1_g000001.1E2F/DP family protein
Rmu_sc0026307.1_g000001.1E2F/DP family protein
Rmu_sc0032585.1_g000001.1E2F/DP family protein
Rmu_ssc0000019.1_g000022.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710