PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Papaver somniferum
E2F/DP Family
Species TF ID Description
XP_026381713.1E2F/DP family protein
XP_026381714.1E2F/DP family protein
XP_026393760.1E2F/DP family protein
XP_026395397.1E2F/DP family protein
XP_026395405.1E2F/DP family protein
XP_026395413.1E2F/DP family protein
XP_026398897.1E2F/DP family protein
XP_026399172.1E2F/DP family protein
XP_026399174.1E2F/DP family protein
XP_026403236.1E2F/DP family protein
XP_026410537.1E2F/DP family protein
XP_026414600.1E2F/DP family protein
XP_026417752.1E2F/DP family protein
XP_026418335.1E2F/DP family protein
XP_026420672.1E2F/DP family protein
XP_026420673.1E2F/DP family protein
XP_026423058.1E2F/DP family protein
XP_026423171.1E2F/DP family protein
XP_026423605.1E2F/DP family protein
XP_026426693.1E2F/DP family protein
XP_026436047.1E2F/DP family protein
XP_026440288.1E2F/DP family protein
XP_026443530.1E2F/DP family protein
XP_026443531.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710