PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Ipomoea nil
E2F/DP Family
Species TF ID Description
XP_019152589.1E2F/DP family protein
XP_019156548.1E2F/DP family protein
XP_019161319.1E2F/DP family protein
XP_019162488.1E2F/DP family protein
XP_019163334.1E2F/DP family protein
XP_019163335.1E2F/DP family protein
XP_019163337.1E2F/DP family protein
XP_019165970.1E2F/DP family protein
XP_019165971.1E2F/DP family protein
XP_019176266.1E2F/DP family protein
XP_019185885.1E2F/DP family protein
XP_019185886.1E2F/DP family protein
XP_019188105.1E2F/DP family protein
XP_019197185.1E2F/DP family protein
XP_019197186.1E2F/DP family protein
XP_019197805.1E2F/DP family protein
XP_019199609.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710