PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Durio zibethinus
E2F/DP Family
Species TF ID Description
XP_022729951.1E2F/DP family protein
XP_022729952.1E2F/DP family protein
XP_022738097.1E2F/DP family protein
XP_022743195.1E2F/DP family protein
XP_022743196.1E2F/DP family protein
XP_022744027.1E2F/DP family protein
XP_022744714.1E2F/DP family protein
XP_022744715.1E2F/DP family protein
XP_022747595.1E2F/DP family protein
XP_022747596.1E2F/DP family protein
XP_022747597.1E2F/DP family protein
XP_022747598.1E2F/DP family protein
XP_022747853.1E2F/DP family protein
XP_022751903.1E2F/DP family protein
XP_022752528.1E2F/DP family protein
XP_022752529.1E2F/DP family protein
XP_022752530.1E2F/DP family protein
XP_022752531.1E2F/DP family protein
XP_022756017.1E2F/DP family protein
XP_022757156.1E2F/DP family protein
XP_022766526.1E2F/DP family protein
XP_022766527.1E2F/DP family protein
XP_022766528.1E2F/DP family protein
XP_022766986.1E2F/DP family protein
XP_022766988.1E2F/DP family protein
XP_022766989.1E2F/DP family protein
XP_022766990.1E2F/DP family protein
XP_022766991.1E2F/DP family protein
XP_022767291.1E2F/DP family protein
XP_022767292.1E2F/DP family protein
XP_022767293.1E2F/DP family protein
XP_022767530.1E2F/DP family protein
XP_022767533.1E2F/DP family protein
XP_022775429.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710