PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Camellia sinensis var. sinensis
E2F/DP Family
Species TF ID Description
XP_028051657.1E2F/DP family protein
XP_028051658.1E2F/DP family protein
XP_028051659.1E2F/DP family protein
XP_028051660.1E2F/DP family protein
XP_028051661.1E2F/DP family protein
XP_028051662.1E2F/DP family protein
XP_028059824.1E2F/DP family protein
XP_028059825.1E2F/DP family protein
XP_028060413.1E2F/DP family protein
XP_028060414.1E2F/DP family protein
XP_028060415.1E2F/DP family protein
XP_028060630.1E2F/DP family protein
XP_028065653.1E2F/DP family protein
XP_028072876.1E2F/DP family protein
XP_028072877.1E2F/DP family protein
XP_028074977.1E2F/DP family protein
XP_028078478.1E2F/DP family protein
XP_028086786.1E2F/DP family protein
XP_028097378.1E2F/DP family protein
XP_028100519.1E2F/DP family protein
XP_028102834.1E2F/DP family protein
XP_028102835.1E2F/DP family protein
XP_028105353.1E2F/DP family protein
XP_028105354.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710