PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Chrysanthemum seticuspe
E2F/DP Family
Species TF ID Description
Cse_sc000026.1_g150.1E2F/DP family protein
Cse_sc002160.1_g020.1E2F/DP family protein
Cse_sc002437.1_g040.1E2F/DP family protein
Cse_sc002551.1_g040.1E2F/DP family protein
Cse_sc007425.1_g030.1E2F/DP family protein
Cse_sc007498.1_g030.1E2F/DP family protein
Cse_sc011032.1_g020.1E2F/DP family protein
Cse_sc013825.1_g030.1E2F/DP family protein
Cse_sc021066.1_g020.1E2F/DP family protein
Cse_sc053684.1_g010.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710