PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Cucurbita moschata
E2F/DP Family
Species TF ID Description
XP_022921523.1E2F/DP family protein
XP_022922511.1E2F/DP family protein
XP_022924093.1E2F/DP family protein
XP_022924094.1E2F/DP family protein
XP_022924095.1E2F/DP family protein
XP_022924096.1E2F/DP family protein
XP_022924097.1E2F/DP family protein
XP_022925566.1E2F/DP family protein
XP_022925567.1E2F/DP family protein
XP_022925568.1E2F/DP family protein
XP_022925569.1E2F/DP family protein
XP_022925570.1E2F/DP family protein
XP_022925571.1E2F/DP family protein
XP_022925572.1E2F/DP family protein
XP_022925574.1E2F/DP family protein
XP_022942389.1E2F/DP family protein
XP_022942391.1E2F/DP family protein
XP_022944699.1E2F/DP family protein
XP_022951712.1E2F/DP family protein
XP_022954791.1E2F/DP family protein
XP_022954792.1E2F/DP family protein
XP_022957729.1E2F/DP family protein
XP_022957731.1E2F/DP family protein
XP_022961660.1E2F/DP family protein
XP_022963278.1E2F/DP family protein
XP_022963279.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710