PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Cucurbita maxima
E2F/DP Family
Species TF ID Description
XP_022966582.1E2F/DP family protein
XP_022966661.1E2F/DP family protein
XP_022972582.1E2F/DP family protein
XP_022972583.1E2F/DP family protein
XP_022979058.1E2F/DP family protein
XP_022979059.1E2F/DP family protein
XP_022979060.1E2F/DP family protein
XP_022979062.1E2F/DP family protein
XP_022979063.1E2F/DP family protein
XP_022979064.1E2F/DP family protein
XP_022979065.1E2F/DP family protein
XP_022979066.1E2F/DP family protein
XP_022984224.1E2F/DP family protein
XP_022986222.1E2F/DP family protein
XP_022988382.1E2F/DP family protein
XP_022994624.1E2F/DP family protein
XP_022994626.1E2F/DP family protein
XP_022995080.1E2F/DP family protein
XP_022995081.1E2F/DP family protein
XP_022996982.1E2F/DP family protein
XP_023000743.1E2F/DP family protein
XP_023000744.1E2F/DP family protein
XP_023000745.1E2F/DP family protein
XP_023000746.1E2F/DP family protein
XP_023002370.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710