Plant Transcription Factor Database
Previous version: v1.0, v2.0, v3.0
Zoysia matrella
M-type_MADS Family
Species TF ID Description
Zmw_sc00009.1.g00170.1M-type_MADS family protein
Zmw_sc00009.1.g00200.1M-type_MADS family protein
Zmw_sc00009.1.g00230.1M-type_MADS family protein
Zmw_sc00044.1.g00540.1M-type_MADS family protein
Zmw_sc00044.1.g00740.1M-type_MADS family protein
Zmw_sc00045.1.g00470.1M-type_MADS family protein
Zmw_sc00060.1.g00180.1M-type_MADS family protein
Zmw_sc00115.1.g00410.1M-type_MADS family protein
Zmw_sc00115.1.g00620.1M-type_MADS family protein
Zmw_sc00189.1.g00280.1M-type_MADS family protein
Zmw_sc00206.1.g00150.1M-type_MADS family protein
Zmw_sc00219.1.g00010.1M-type_MADS family protein
Zmw_sc00231.1.g00120.1M-type_MADS family protein
Zmw_sc00338.1.g00040.1M-type_MADS family protein
Zmw_sc00428.1.g00020.1M-type_MADS family protein
Zmw_sc00436.1.g00230.1M-type_MADS family protein
Zmw_sc00441.1.g00100.1M-type_MADS family protein
Zmw_sc00451.1.g00140.1M-type_MADS family protein
Zmw_sc00458.1.g00110.1M-type_MADS family protein
Zmw_sc00482.1.g00190.1M-type_MADS family protein
Zmw_sc00487.1.g00270.1M-type_MADS family protein
Zmw_sc00502.1.g00060.1M-type_MADS family protein
Zmw_sc00536.1.g00090.1M-type_MADS family protein
Zmw_sc00594.1.g00050.1M-type_MADS family protein
Zmw_sc00616.1.g00200.1M-type_MADS family protein
Zmw_sc00666.1.g00050.1M-type_MADS family protein
Zmw_sc00671.1.g00200.1M-type_MADS family protein
Zmw_sc00699.1.g00080.1M-type_MADS family protein
Zmw_sc00700.1.g00150.1M-type_MADS family protein
Zmw_sc00716.1.g00200.1M-type_MADS family protein
Zmw_sc00729.1.g00210.1M-type_MADS family protein
Zmw_sc00768.1.g00040.1M-type_MADS family protein
Zmw_sc00778.1.g00100.1M-type_MADS family protein
Zmw_sc00780.1.g00010.1M-type_MADS family protein
Zmw_sc00877.1.g00180.1M-type_MADS family protein
Zmw_sc00929.1.g00050.1M-type_MADS family protein
Zmw_sc00950.1.g00030.1M-type_MADS family protein
Zmw_sc00963.1.g00020.1M-type_MADS family protein
Zmw_sc00964.1.g00040.1M-type_MADS family protein
Zmw_sc00964.1.g00070.1M-type_MADS family protein
Zmw_sc00964.1.g00090.1M-type_MADS family protein
Zmw_sc00964.1.g00110.1M-type_MADS family protein
Zmw_sc01007.1.g00010.1M-type_MADS family protein
Zmw_sc01046.1.g00090.1M-type_MADS family protein
Zmw_sc01057.1.g00230.1M-type_MADS family protein
Zmw_sc01080.1.g00040.1M-type_MADS family protein
Zmw_sc01131.1.g00010.1M-type_MADS family protein
Zmw_sc01180.1.g00230.1M-type_MADS family protein
Zmw_sc01192.1.g00180.1M-type_MADS family protein
Zmw_sc01237.1.g00050.1M-type_MADS family protein
Zmw_sc01327.1.g00040.1M-type_MADS family protein
Zmw_sc01346.1.g00020.1M-type_MADS family protein
Zmw_sc01382.1.g00140.1M-type_MADS family protein
Zmw_sc01433.1.g00050.1M-type_MADS family protein
Zmw_sc01433.1.g00060.1M-type_MADS family protein
Zmw_sc01443.1.g00030.1M-type_MADS family protein
Zmw_sc01462.1.g00290.1M-type_MADS family protein
Zmw_sc01511.1.g00110.1M-type_MADS family protein
Zmw_sc01694.1.g00080.1M-type_MADS family protein
Zmw_sc01817.1.g00060.1M-type_MADS family protein
Zmw_sc01856.1.g00060.1M-type_MADS family protein
Zmw_sc01860.1.g00070.1M-type_MADS family protein
Zmw_sc01896.1.g00020.1M-type_MADS family protein
Zmw_sc01934.1.g00180.1M-type_MADS family protein
Zmw_sc01949.1.g00100.1M-type_MADS family protein
Zmw_sc01961.1.g00020.1M-type_MADS family protein
Zmw_sc01992.1.g00030.1M-type_MADS family protein
Zmw_sc02100.1.g00050.1M-type_MADS family protein
Zmw_sc02169.1.g00130.1M-type_MADS family protein
Zmw_sc02226.1.g00090.1M-type_MADS family protein
Zmw_sc02334.1.g00040.1M-type_MADS family protein
Zmw_sc02419.1.g00090.1M-type_MADS family protein
Zmw_sc02471.1.g00020.1M-type_MADS family protein
Zmw_sc02577.1.g00010.1M-type_MADS family protein
Zmw_sc02590.1.g00090.1M-type_MADS family protein
Zmw_sc02590.1.g00100.1M-type_MADS family protein
Zmw_sc02590.1.g00110.1M-type_MADS family protein
Zmw_sc02601.1.g00030.1M-type_MADS family protein
Zmw_sc02690.1.g00010.1M-type_MADS family protein
Zmw_sc02867.1.g00040.1M-type_MADS family protein
Zmw_sc02906.1.g00120.1M-type_MADS family protein
Zmw_sc03090.1.g00080.1M-type_MADS family protein
Zmw_sc03182.1.g00040.1M-type_MADS family protein
Zmw_sc03185.1.g00010.1M-type_MADS family protein
Zmw_sc03297.1.g00010.1M-type_MADS family protein
Zmw_sc03305.1.g00060.1M-type_MADS family protein
Zmw_sc03527.1.g00040.1M-type_MADS family protein
Zmw_sc03775.1.g00070.1M-type_MADS family protein
Zmw_sc03810.1.g00070.1M-type_MADS family protein
Zmw_sc03981.1.g00120.1M-type_MADS family protein
Zmw_sc04228.1.g00060.1M-type_MADS family protein
Zmw_sc04261.1.g00030.1M-type_MADS family protein
Zmw_sc04284.1.g00030.1M-type_MADS family protein
Zmw_sc04334.1.g00070.1M-type_MADS family protein
Zmw_sc04412.1.g00070.1M-type_MADS family protein
Zmw_sc04415.1.g00010.1M-type_MADS family protein
Zmw_sc04458.1.g00060.1M-type_MADS family protein
Zmw_sc04550.1.g00040.1M-type_MADS family protein
Zmw_sc04815.1.g00110.1M-type_MADS family protein
Zmw_sc05178.1.g00040.1M-type_MADS family protein
Zmw_sc05645.1.g00040.1M-type_MADS family protein
Zmw_sc05670.1.g00010.1M-type_MADS family protein
Zmw_sc05676.1.g00030.1M-type_MADS family protein
Zmw_sc05849.1.g00040.1M-type_MADS family protein
Zmw_sc06001.1.g00010.1M-type_MADS family protein
Zmw_sc06044.1.g00060.1M-type_MADS family protein
Zmw_sc06112.1.g00010.1M-type_MADS family protein
Zmw_sc06169.1.g00060.1M-type_MADS family protein
Zmw_sc06178.1.g00020.1M-type_MADS family protein
Zmw_sc06896.1.g00020.1M-type_MADS family protein
Zmw_sc07093.1.g00010.1M-type_MADS family protein
Zmw_sc07096.1.g00010.1M-type_MADS family protein
Zmw_sc07315.1.g00020.1M-type_MADS family protein
Zmw_sc07487.1.g00010.1M-type_MADS family protein
Zmw_sc07647.1.g00020.1M-type_MADS family protein
Zmw_sc07859.1.g00010.1M-type_MADS family protein
M-type_MADS (M-type MADS) Family Introduction

The best studied plant MADS-box transcription factors are those involved in floral organ identity determination. Analysis of homeotic floral mutants resulted in the formulation of a genetic model, named the ABC model, that explains how the combined functions of three classes of genes (A, B, and C) determine the identity of the four flower organs (reviewed by Coen and Meyerowitz, 1991). Arabidopsis has two A-class genes (AP1 and AP2 [Bowman et al., 1989]), two B-class genes (PI and AP3), and a single C-class gene (AG), of which only AP2 is not a MADS-box gene. Recently, it was shown that the Arabidopsis B- and C-function genes, which control petal, stamen, and carpel development, are functionally dependent on three highly similar MADS-box genes, SEP1, SEP2, and SEP3 (Pelaz et al., 2000). Interestingly, only when mutant knockout alleles of the three SEP genes were combined in a triple sep1 sep2 sep3 mutant was loss of petal, stamen, and carpel identity observed, resulting in a flower composed of only sepals. This example shows that redundancy occurs in the MADS-box gene family, which complicates reverse genetic strategies for gene function analysis. The SHP genes provide another example of MADS-box gene redundancy. shp1 and shp2 single mutants do not exhibit any phenotypic effect, whereas in the double mutant, development of the dehiscence zone is disturbed in the fruit, resulting in a failure to release seeds (Liljegren et al., 2000)[1].

It has been proposed that there are at least 2 lineages (type I and type II) of MADS-box genes in plants, animals, and fungi. Most of the well-studied plant genes are type II genes and have three more domains than type I genes from the N to the C terminus of the protein:intervening (I) domain (~30 codons), keratin-lik e coiled-coil (K) domain (~70 codons), and Cterminal (C) domain (variable length). These genes are called the MIKC-type and are specific to plants[2].

The MADS-box is a DNA binding domain of 58 amino acids that binds DNA at consensus recognition sequences known as CArG boxes [CC(A/T)6GG] (Hayes et al., 1988; Riechmann et al., 1996b). The interaction with DNA has been studied in detail for the human and yeast MADS-box proteins thanks to the resolved crystal structures (Pellegrini et al., 1995; Santelli and Richmond, 2000). The I domain is less conserved and contributes to the specification of dimerization. The K domain is characterized by a coiled-coil structure, which facilitates the dimerization of MADS-box proteins (Davies et al., 1996; Fan et al., 1997). The C domain is the least conserved domain; in some cases, it has been shown to contain a transactivation domain or to contribute to the formation of multimeric MADS-box protein complexes (Egea-Cortines et al., 1999; Honma and Goto, 2001)[1].

1.Parenicova L, de Folter S, Kieffer M, Horner DS, Favalli C, Busscher J, Cook HE, Ingram RM, Kater MM, Davies B, Angenent GC, Colombo L.
Molecular and phylogenetic analyses of the complete MADS-box transcription factor family in Arabidopsis: new openings to the MADS world.
Plant Cell. 2003 Jul;15(7):1538-51.
PMID: 12837945
2.Nam J, dePamphilis CW, Ma H, Nei M.
Antiquity and evolution of the MADS-box gene family controlling flower development in plants.
Mol Biol Evol. 2003 Sep;20(9):1435-47. Epub 2003 May 30.
PMID: 12777513