PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Zoysia matrella
GeBP Family
Species TF ID Description
Zmw_sc00069.1.g00200.1GeBP family protein
Zmw_sc00078.1.g00330.1GeBP family protein
Zmw_sc00078.1.g00350.1GeBP family protein
Zmw_sc00148.1.g00350.1GeBP family protein
Zmw_sc00220.1.g00040.1GeBP family protein
Zmw_sc00471.1.g00140.1GeBP family protein
Zmw_sc00505.1.g00370.1GeBP family protein
Zmw_sc00656.1.g00260.1GeBP family protein
Zmw_sc00664.1.g00050.1GeBP family protein
Zmw_sc00748.1.g00070.1GeBP family protein
Zmw_sc00790.1.g00100.1GeBP family protein
Zmw_sc01063.1.g00210.1GeBP family protein
Zmw_sc01063.1.g00220.1GeBP family protein
Zmw_sc01573.1.g00060.1GeBP family protein
Zmw_sc01641.1.g00200.1GeBP family protein
Zmw_sc01648.1.g00010.1GeBP family protein
Zmw_sc01771.1.g00070.1GeBP family protein
Zmw_sc01882.1.g00020.1GeBP family protein
Zmw_sc01936.1.g00010.1GeBP family protein
Zmw_sc02478.1.g00020.1GeBP family protein
Zmw_sc02510.1.g00110.1GeBP family protein
Zmw_sc03492.1.g00090.1GeBP family protein
Zmw_sc03624.1.g00010.1GeBP family protein
Zmw_sc03724.1.g00060.1GeBP family protein
Zmw_sc04067.1.g00070.1GeBP family protein
Zmw_sc04635.1.g00090.1GeBP family protein
Zmw_sc05704.1.g00010.1GeBP family protein
Zmw_sc05735.1.g00030.1GeBP family protein
Zmw_sc07906.1.g00030.1GeBP family protein
Zmw_sc10454.1.g00010.1GeBP family protein
GeBP Family Introduction

Understanding the role of transcription factors (TFs) is essential in reconstructing developmental regulatory networks. The plant-specific GeBP TF family of Arabidopsis thaliana (Arabidopsis) comprises 21 members, all of unknown function. A subset of four members, the founding member GeBP and GeBP-like proteins (GPL) 1, 2, and 3, shares a conserved C-terminal domain. Here we report that GeBP/GPL genes represent a newly defined class of leucine-zipper (Leu-zipper) TFs and that they play a redundant role in cytokinin hormone pathway regulation. Specifically, we demonstrate using yeast, in vitro, and split-yellow fluorescent protein in planta assays that GeBP/GPL proteins form homo- and heterodimers through a noncanonical Leu-zipper motif located in the C-terminal domain. A triple loss-of-function mutant of the three most closely related genes gebp gpl1 gpl2 shows a reduced sensitivity to exogenous cytokinins in a subset of cytokinin responses such as senescence and growth, whereas root inhibition is not affected. We find that transcript levels of type-A cytokinin response genes, which are involved in the negative feedback regulation of cytokinin signaling, are higher in the triple mutant. Using a GPL version that acts as a constitutive transcriptional activator, we show that the regulation of Arabidopsis response regulators (ARRs) is mediated by at least one additional, as yet unknown, repressor acting genetically downstream in the GeBP/GPL pathway. Our results indicate that GeBP/GPL genes encode a new class of unconventional Leu-zipper TF proteins and suggest that their role in the cytokinin pathway is to antagonize the negative feedback regulation on ARR genes to trigger the cytokinin response.

Chevalier F, Perazza D, Laporte F, Le Henanff G, Hornitschek P, Bonneville JM, Herzog M, Vachon G
GeBP and GeBP-Like Proteins Are Noncanonical Leucine-Zipper Transcription Factors That Regulate Cytokinin Response in Arabidopsis
Plant Physiol. 2008 Mar;146(3):1142-54.
PMID: 18162594