PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Zea mays
WOX Family
Species TF ID Description
GRMZM2G069028_P03WOX family protein
GRMZM2G069028_P01WOX family protein
GRMZM2G122537_P02WOX family protein
GRMZM2G140083_P01WOX family protein
GRMZM2G047448_P01WOX family protein
GRMZM2G028622_P01WOX family protein
GRMZM2G478396_P01WOX family protein
GRMZM2G116063_P01WOX family protein
GRMZM2G133972_P02WOX family protein
GRMZM2G133972_P01WOX family protein
GRMZM2G108933_P01WOX family protein
GRMZM2G031882_P01WOX family protein
GRMZM2G031882_P02WOX family protein
GRMZM2G314064_P01WOX family protein
GRMZM2G162481_P01WOX family protein
GRMZM2G162481_P02WOX family protein
GRMZM2G409881_P02WOX family protein
GRMZM2G010929_P02WOX family protein
GRMZM2G409881_P01WOX family protein
GRMZM2G170958_P01WOX family protein
GRMZM5G805026_P01WOX family protein
GRMZM5G805026_P02WOX family protein
GRMZM2G038252_P01WOX family protein
GRMZM2G069274_P02WOX family protein
GRMZM2G038252_P02WOX family protein
GRMZM2G069274_P01WOX family protein
GRMZM2G339751_P01WOX family protein
GRMZM2G069028_P02WOX family protein
GRMZM2G122537_P01WOX family protein
GRMZM2G419252_P01WOX family protein
WOX Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401


The WOX genes form a plant-specific subclade of the eukaryotic homeobox transcription factor superfamily, which is characterized by the presence of a conserved DNA-binding homeodomain. The analysis of WOX gene expression and function shows that WOX family members fulfill specialized functions in key developmental processes in plants, such as embryonic patterning, stem-cell maintenance and organ formation. These functions can be related to either promotion of cell division activity and/or prevention of premature cell differentiation.

van der Graaff E, Laux T, Rensing SA.
The WUS homeobox-containing (WOX) protein family.
Genome Biol, 2009. 10(12): p. 248.
PMID: 20067590