PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Zea mays
E2F/DP Family
Species TF ID Description
AC214168.3_FGP001E2F/DP family protein
AC233850.1_FGP005E2F/DP family protein
GRMZM2G001699_P01E2F/DP family protein
GRMZM2G001699_P02E2F/DP family protein
GRMZM2G041701_P01E2F/DP family protein
GRMZM2G041701_P02E2F/DP family protein
GRMZM2G050590_P01E2F/DP family protein
GRMZM2G052515_P01E2F/DP family protein
GRMZM2G060000_P01E2F/DP family protein
GRMZM2G060000_P02E2F/DP family protein
GRMZM2G063387_P01E2F/DP family protein
GRMZM2G086072_P01E2F/DP family protein
GRMZM2G139024_P01E2F/DP family protein
GRMZM2G148506_P01E2F/DP family protein
GRMZM2G148506_P02E2F/DP family protein
GRMZM2G169709_P01E2F/DP family protein
GRMZM2G333591_P01E2F/DP family protein
GRMZM2G351232_P01E2F/DP family protein
GRMZM2G361659_P01E2F/DP family protein
GRMZM2G378665_P01E2F/DP family protein
GRMZM2G404769_P01E2F/DP family protein
GRMZM2G404769_P02E2F/DP family protein
GRMZM2G462623_P01E2F/DP family protein
GRMZM5G829408_P01E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710