PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Zea mays
AP2 Family
Species TF ID Description
AC215909.3_FGP001AP2 family protein
GRMZM2G021573_P01AP2 family protein
GRMZM2G022359_P01AP2 family protein
GRMZM2G028151_P01AP2 family protein
GRMZM2G073982_P01AP2 family protein
GRMZM2G086573_P01AP2 family protein
GRMZM2G113078_P01AP2 family protein
GRMZM2G124524_P01AP2 family protein
GRMZM2G124524_P03AP2 family protein
GRMZM2G130459_P01AP2 family protein
GRMZM2G130459_P02AP2 family protein
GRMZM2G130459_P03AP2 family protein
GRMZM2G131266_P01AP2 family protein
GRMZM2G131266_P02AP2 family protein
GRMZM2G139082_P01AP2 family protein
GRMZM2G139082_P02AP2 family protein
GRMZM2G141219_P01AP2 family protein
GRMZM2G141219_P02AP2 family protein
GRMZM2G141638_P01AP2 family protein
GRMZM2G160730_P01AP2 family protein
GRMZM2G160730_P02AP2 family protein
GRMZM2G174784_P01AP2 family protein
GRMZM2G174834_P02AP2 family protein
GRMZM2G174834_P03AP2 family protein
GRMZM2G176175_P01AP2 family protein
GRMZM2G176175_P02AP2 family protein
GRMZM2G317160_P01AP2 family protein
GRMZM2G366434_P01AP2 family protein
GRMZM2G415251_P01AP2 family protein
GRMZM2G416701_P01AP2 family protein
GRMZM2G451031_P01AP2 family protein
GRMZM2G461905_P01AP2 family protein
GRMZM2G700665_P03AP2 family protein
GRMZM2G703514_P01AP2 family protein
GRMZM2G703514_P02AP2 family protein
GRMZM2G703514_P03AP2 family protein
GRMZM2G703514_P04AP2 family protein
GRMZM5G862109_P01AP2 family protein
GRMZM5G862109_P03AP2 family protein
GRMZM2G146688_P01AP2 family protein
GRMZM2G013657_P01AP2 family protein
GRMZM2G013657_P04AP2 family protein
GRMZM2G700665_P02AP2 family protein
GRMZM2G013657_P02AP2 family protein
GRMZM5G862109_P02AP2 family protein
GRMZM2G021573_P03AP2 family protein
GRMZM2G416701_P02AP2 family protein
GRMZM2G076602_P01AP2 family protein
GRMZM2G174834_P04AP2 family protein
GRMZM2G399072_P02AP2 family protein
GRMZM2G174784_P02AP2 family protein
GRMZM2G174784_P03AP2 family protein
GRMZM2G174784_P04AP2 family protein
GRMZM2G700665_P01AP2 family protein
AP2 Family Introduction

The AP2/ERF superfamily is defined by the AP2/ERF domain, which consists of about 60 to 70 amino acids and is involved in DNA binding. These three families have been defined as follows. The AP2 family proteins contain two repeated AP2/ERF domains, the ERF family proteins contain a single AP2/ERF domain, and the RAV family proteins contain a B3 domain, which is a DNA-binding domain conserved in other plant-specific transcription factors, in addition to the single AP2/ERF domain.

It has been demonstrated that the AP2/ERF proteins have important functions in the transcriptional regulation of a variety of biological processes related to growth and development, as well as various responses to environmental stimuli.

Genes in the AP2 family have been shown to participate in the regulation of developmental processes, e.g. flower development, spikelet meristem determinacy, leaf epidermal cell identity, and embryo development.

Toshitsugu Nakano, Kaoru Suzuki, Tatsuhito Fujimura, and Hideaki Shinshi.
Genome-wide analysis of the ERF gene family in Arabidopsis and rice.
Plant Physiol, 2006. 140(2): p. 411-32.
PMID: 16407444


Using an in vitro selection procedure, the DNA binding specificity of the two AP2 repeat containing protein ANT was found to be 5'-gCAC(A/G)N(A/T)TcCC(a/g)ANG(c/t)-3'. This consensus site is much longer than sites recognized by proteins containing a single AP2 repeat and neither AP2 repeat of ANT was alone capable of binding to the selected sequences, suggesting that both AP2 repeats make DNA contacts.

Nole-Wilson S, Krizek BA.
DNA binding properties of the Arabidopsis floral development protein AINTEGUMENTA.
Nucleic Acids Res. 2000 Nov 1;28(21):4076-82. Erratum in: Nucleic Acids Res 2001 Mar 1;29(5):1261.
PMID: 11058102