PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Ziziphus jujuba
FAR1 Family
Species TF ID Description
XP_015865732.1FAR1 family protein
XP_015866013.1FAR1 family protein
XP_015866451.1FAR1 family protein
XP_015869655.1FAR1 family protein
XP_015870221.1FAR1 family protein
XP_015870227.1FAR1 family protein
XP_015870555.1FAR1 family protein
XP_015870561.1FAR1 family protein
XP_015870622.1FAR1 family protein
XP_015870629.1FAR1 family protein
XP_015872573.1FAR1 family protein
XP_015873302.1FAR1 family protein
XP_015873603.1FAR1 family protein
XP_015873856.1FAR1 family protein
XP_015875767.1FAR1 family protein
XP_015875768.1FAR1 family protein
XP_015875937.1FAR1 family protein
XP_015876190.1FAR1 family protein
XP_015876191.1FAR1 family protein
XP_015877183.1FAR1 family protein
XP_015877510.1FAR1 family protein
XP_015877776.1FAR1 family protein
XP_015877995.1FAR1 family protein
XP_015877996.1FAR1 family protein
XP_015878435.1FAR1 family protein
XP_015878564.1FAR1 family protein
XP_015878565.1FAR1 family protein
XP_015879048.1FAR1 family protein
XP_015879264.1FAR1 family protein
XP_015880093.1FAR1 family protein
XP_015880286.1FAR1 family protein
XP_015880904.1FAR1 family protein
XP_015880907.1FAR1 family protein
XP_015880908.1FAR1 family protein
XP_015880909.1FAR1 family protein
XP_015881527.1FAR1 family protein
XP_015883047.1FAR1 family protein
XP_015883401.1FAR1 family protein
XP_015885834.1FAR1 family protein
XP_015886948.1FAR1 family protein
XP_015886949.1FAR1 family protein
XP_015886950.1FAR1 family protein
XP_015886951.1FAR1 family protein
XP_015886952.1FAR1 family protein
XP_015886953.1FAR1 family protein
XP_015886954.1FAR1 family protein
XP_015886981.1FAR1 family protein
XP_015886983.1FAR1 family protein
XP_015886985.1FAR1 family protein
XP_015886990.1FAR1 family protein
XP_015886991.1FAR1 family protein
XP_015886992.1FAR1 family protein
XP_015886994.1FAR1 family protein
XP_015886995.1FAR1 family protein
XP_015888263.1FAR1 family protein
XP_015888264.1FAR1 family protein
XP_015888265.1FAR1 family protein
XP_015889512.1FAR1 family protein
XP_015889513.1FAR1 family protein
XP_015889514.1FAR1 family protein
XP_015891738.1FAR1 family protein
XP_015892031.1FAR1 family protein
XP_015892032.1FAR1 family protein
XP_015892033.1FAR1 family protein
XP_015892966.1FAR1 family protein
XP_015893354.1FAR1 family protein
XP_015893684.1FAR1 family protein
XP_015893685.1FAR1 family protein
XP_015893687.1FAR1 family protein
XP_015893694.1FAR1 family protein
XP_015893698.1FAR1 family protein
XP_015893699.1FAR1 family protein
XP_015893770.1FAR1 family protein
XP_015894224.1FAR1 family protein
XP_015894225.1FAR1 family protein
XP_015894226.1FAR1 family protein
XP_015894227.1FAR1 family protein
XP_015894228.1FAR1 family protein
XP_015897499.1FAR1 family protein
XP_015897844.1FAR1 family protein
XP_015899962.1FAR1 family protein
XP_015899963.1FAR1 family protein
XP_015899964.1FAR1 family protein
XP_015900231.1FAR1 family protein
XP_015900632.1FAR1 family protein
XP_015900633.1FAR1 family protein
XP_015900634.1FAR1 family protein
XP_015900729.1FAR1 family protein
XP_015900730.1FAR1 family protein
XP_015901246.1FAR1 family protein
XP_015901565.1FAR1 family protein
XP_015901650.1FAR1 family protein
XP_015902716.1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885