PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Vigna unguiculata
bZIP Family
Species TF ID Description
Vun000075bZIP family protein
Vun000256bZIP family protein
Vun000318bZIP family protein
Vun001345bZIP family protein
Vun001425bZIP family protein
Vun001539bZIP family protein
Vun001564bZIP family protein
Vun001841bZIP family protein
Vun002062bZIP family protein
Vun002631bZIP family protein
Vun002742bZIP family protein
Vun003060bZIP family protein
Vun003648bZIP family protein
Vun004221bZIP family protein
Vun004249bZIP family protein
Vun004430bZIP family protein
Vun004506bZIP family protein
Vun004558bZIP family protein
Vun005689bZIP family protein
Vun005959bZIP family protein
Vun006014bZIP family protein
Vun006040bZIP family protein
Vun006278bZIP family protein
Vun007894bZIP family protein
Vun008852bZIP family protein
Vun008884bZIP family protein
Vun010311bZIP family protein
Vun010756bZIP family protein
Vun010764bZIP family protein
Vun011223bZIP family protein
Vun011253bZIP family protein
Vun011284bZIP family protein
Vun011307bZIP family protein
Vun011478bZIP family protein
bZIP Family Introduction

The bZIP domain consists of two structural features located on a contiguous alpha-helix: first, a basic region of ~ 16 amino acid residues containing a nuclear localization signal followed by an invariant N-x7-R/K motif that contacts the DNA; and, second, a heptad repeat of leucines or other bulky hydrophobic amino acids positioned exactly nine amino acids towards the C-terminus, creating an amphipathic helix. To bind DNA, two subunits adhere via interactions between the hydrophobic sides of their helices, which creates a superimposing coiled-coil structure. The ability to form homo- and heterodimers is influenced by the electrostatic attraction and repulsion of polar residues flanking the hydrophobic interaction surface of the helices.

Plant bZIP proteins preferentially bind to DNA sequences with an ACGT core. Binding specificity is regulated by flanking nucleotides. Plant bZIPs preferentially bind to the A-box (TACGTA), C-box (GACGTC) and G-box (CACGTG), but there are also examples of nonpalindromic binding sites.

Jakoby M, Weisshaar B, Droge-Laser W, Vicente-Carbajosa J, Tiedemann J, Kroj T, Parcy F
bZIP transcription factors in Arabidopsis.
Trends Plant Sci, 2002. 7(3): p. 106-11.
PMID: 11906833