PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Vigna radiata
HD-ZIP Family
Species TF ID Description
Vradi01g00920.1HD-ZIP family protein
Vradi0308s00040.1HD-ZIP family protein
Vradi07g05760.1HD-ZIP family protein
Vradi02g12480.1HD-ZIP family protein
Vradi11g10760.1HD-ZIP family protein
Vradi07g18660.1HD-ZIP family protein
Vradi07g05520.1HD-ZIP family protein
Vradi01g01680.1HD-ZIP family protein
Vradi0349s00140.1HD-ZIP family protein
Vradi05g18150.1HD-ZIP family protein
Vradi07g15340.1HD-ZIP family protein
Vradi07g12330.1HD-ZIP family protein
Vradi03g00270.1HD-ZIP family protein
Vradi07g11540.1HD-ZIP family protein
Vradi04g08650.1HD-ZIP family protein
Vradi10g00680.1HD-ZIP family protein
Vradi06g14330.1HD-ZIP family protein
Vradi09g05540.1HD-ZIP family protein
Vradi07g04360.1HD-ZIP family protein
Vradi0179s00040.1HD-ZIP family protein
Vradi08g05990.1HD-ZIP family protein
Vradi03g04130.1HD-ZIP family protein
Vradi0083s00170.1HD-ZIP family protein
Vradi03g04080.1HD-ZIP family protein
Vradi02g10520.1HD-ZIP family protein
Vradi07g00330.1HD-ZIP family protein
Vradi11g05430.1HD-ZIP family protein
Vradi07g22800.1HD-ZIP family protein
Vradi04g08400.1HD-ZIP family protein
Vradi11g03840.1HD-ZIP family protein
Vradi05g20420.1HD-ZIP family protein
Vradi02g07900.1HD-ZIP family protein
Vradi07g09200.1HD-ZIP family protein
Vradi05g22620.1HD-ZIP family protein
Vradi09g09920.1HD-ZIP family protein
Vradi0122s00300.1HD-ZIP family protein
Vradi01g02800.1HD-ZIP family protein
Vradi09g01470.1HD-ZIP family protein
Vradi05g20610.1HD-ZIP family protein
Vradi05g08670.1HD-ZIP family protein
Vradi10g06480.1HD-ZIP family protein
Vradi08g19030.1HD-ZIP family protein
Vradi11g08600.1HD-ZIP family protein
Vradi10g05890.1HD-ZIP family protein
Vradi10g05910.1HD-ZIP family protein
Vradi01g05760.1HD-ZIP family protein
Vradi01g14740.1HD-ZIP family protein
Vradi02g05850.1HD-ZIP family protein
Vradi0450s00050.1HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401