PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Vigna angularis
bHLH Family
Species TF ID Description
Vang0002ss01810.1bHLH family protein
Vang0004ss00980.1bHLH family protein
Vang0004ss01090.1bHLH family protein
Vang0005s01620.1bHLH family protein
Vang0005s01920.1bHLH family protein
Vang0005s01920.2bHLH family protein
Vang0005s01920.3bHLH family protein
Vang0005s01920.4bHLH family protein
Vang0010ss00010.1bHLH family protein
Vang0010ss00970.1bHLH family protein
Vang0010ss00970.2bHLH family protein
Vang0017s00470.1bHLH family protein
Vang0021ss02470.1bHLH family protein
Vang0022ss02120.1bHLH family protein
Vang0027ss00450.1bHLH family protein
Vang0027ss00510.1bHLH family protein
Vang0029ss00610.1bHLH family protein
Vang0029ss00610.2bHLH family protein
Vang0032ss00010.1bHLH family protein
Vang0032ss01120.1bHLH family protein
Vang0032ss01120.3bHLH family protein
Vang0033ss00680.1bHLH family protein
Vang0033ss01490.1bHLH family protein
Vang0057s00340.1bHLH family protein
Vang0057ss00930.1bHLH family protein
Vang0058ss00020.1bHLH family protein
Vang0064ss00600.1bHLH family protein
Vang0065s00530.1bHLH family protein
Vang0069ss00620.1bHLH family protein
Vang0069ss00640.1bHLH family protein
Vang0069ss01680.2bHLH family protein
Vang0069ss02080.1bHLH family protein
Vang0070s00260.1bHLH family protein
Vang0087s00500.1bHLH family protein
Vang0109s00200.1bHLH family protein
Vang0109s00290.1bHLH family protein
Vang0110s00170.1bHLH family protein
Vang0110s00170.2bHLH family protein
Vang0110s00170.3bHLH family protein
Vang0110s00370.1bHLH family protein
Vang0112s00120.1bHLH family protein
Vang0112s00180.1bHLH family protein
Vang0121s00750.1bHLH family protein
Vang0155s00240.1bHLH family protein
Vang0156s00490.1bHLH family protein
Vang0156s00490.2bHLH family protein
Vang0156s00490.3bHLH family protein
Vang0156s00490.4bHLH family protein
Vang0159s00020.1bHLH family protein
Vang0159s00030.1bHLH family protein
Vang0182s00710.1bHLH family protein
Vang0198s00070.1bHLH family protein
Vang01g01970.1bHLH family protein
Vang01g01970.2bHLH family protein
Vang01g05030.1bHLH family protein
Vang01g05820.1bHLH family protein
Vang01g10450.1bHLH family protein
Vang01g12240.1bHLH family protein
Vang01g16740.1bHLH family protein
Vang01g18260.1bHLH family protein
Vang01g18260.2bHLH family protein
Vang01g18960.1bHLH family protein
Vang0203s00300.1bHLH family protein
Vang0221s00200.1bHLH family protein
Vang0236s00030.1bHLH family protein
Vang0236s00370.1bHLH family protein
Vang0238s00200.1bHLH family protein
Vang0254s00280.1bHLH family protein
Vang0279s00020.1bHLH family protein
Vang0291s00220.1bHLH family protein
Vang02g02060.1bHLH family protein
Vang02g03600.1bHLH family protein
Vang02g03600.2bHLH family protein
Vang02g03640.1bHLH family protein
Vang02g05040.1bHLH family protein
Vang02g05950.1bHLH family protein
Vang02g07630.1bHLH family protein
Vang02g08600.1bHLH family protein
Vang02g08910.1bHLH family protein
Vang02g15380.1bHLH family protein
Vang0323s00120.1bHLH family protein
Vang0393s00070.1bHLH family protein
Vang03g04780.1bHLH family protein
Vang03g05010.1bHLH family protein
Vang03g05020.1bHLH family protein
Vang03g06020.1bHLH family protein
Vang03g09360.1bHLH family protein
Vang03g11990.1bHLH family protein
Vang03g15430.1bHLH family protein
Vang03g15430.2bHLH family protein
Vang03g15430.3bHLH family protein
Vang03g15430.4bHLH family protein
Vang03g15430.5bHLH family protein
Vang03g15430.6bHLH family protein
Vang03g15430.7bHLH family protein
Vang03g17430.1bHLH family protein
Vang0483s00100.1bHLH family protein
Vang0488s00030.1bHLH family protein
Vang04g02850.1bHLH family protein
Vang04g04640.1bHLH family protein
Vang04g04780.1bHLH family protein
Vang04g05590.1bHLH family protein
Vang04g08000.1bHLH family protein
Vang04g08900.1bHLH family protein
Vang04g10070.1bHLH family protein
Vang04g10070.2bHLH family protein
Vang04g11540.1bHLH family protein
Vang04g11540.2bHLH family protein
Vang04g12090.1bHLH family protein
Vang04g13720.1bHLH family protein
Vang04g14130.1bHLH family protein
Vang04g17410.1bHLH family protein
Vang04g17760.1bHLH family protein
Vang0537s00150.1bHLH family protein
Vang05g00580.1bHLH family protein
Vang05g01400.1bHLH family protein
Vang05g05490.1bHLH family protein
Vang05g07510.1bHLH family protein
Vang05g10350.1bHLH family protein
Vang06g00230.1bHLH family protein
Vang06g02040.1bHLH family protein
Vang06g02360.1bHLH family protein
Vang06g02360.2bHLH family protein
Vang06g04090.1bHLH family protein
Vang06g05550.1bHLH family protein
Vang06g05600.1bHLH family protein
Vang06g06010.1bHLH family protein
Vang06g06160.1bHLH family protein
Vang06g10070.1bHLH family protein
Vang06g10070.2bHLH family protein
Vang06g10700.1bHLH family protein
Vang06g11680.1bHLH family protein
Vang06g15210.1bHLH family protein
Vang06g15210.2bHLH family protein
Vang06g15470.1bHLH family protein
Vang06g16490.1bHLH family protein
Vang06g16490.2bHLH family protein
Vang06g16490.3bHLH family protein
Vang06g16490.4bHLH family protein
Vang06g16490.5bHLH family protein
Vang06g16810.1bHLH family protein
Vang06g17500.1bHLH family protein
Vang06g17620.1bHLH family protein
Vang06g18480.1bHLH family protein
Vang06g23190.1bHLH family protein
Vang06g24030.1bHLH family protein
Vang06g25600.1bHLH family protein
Vang0733s00050.1bHLH family protein
Vang07g02130.1bHLH family protein
Vang07g02170.1bHLH family protein
Vang07g03330.1bHLH family protein
Vang07g03340.1bHLH family protein
Vang07g05950.1bHLH family protein
Vang07g05950.2bHLH family protein
Vang0869s00010.1bHLH family protein
Vang0869s00010.2bHLH family protein
Vang08g02340.1bHLH family protein
Vang08g04650.1bHLH family protein
Vang08g06140.1bHLH family protein
Vang08g06540.1bHLH family protein
Vang08g06590.1bHLH family protein
Vang08g06620.1bHLH family protein
Vang08g06730.1bHLH family protein
Vang09g00610.1bHLH family protein
Vang09g01190.1bHLH family protein
Vang09g02240.1bHLH family protein
Vang09g02270.1bHLH family protein
Vang09g02300.1bHLH family protein
Vang09g02970.1bHLH family protein
Vang09g03030.1bHLH family protein
Vang09g04480.1bHLH family protein
Vang09g05900.1bHLH family protein
Vang09g07070.1bHLH family protein
Vang10g01500.1bHLH family protein
Vang10g02020.1bHLH family protein
Vang10g02020.2bHLH family protein
Vang10g02020.3bHLH family protein
Vang10g04390.1bHLH family protein
Vang10g04980.1bHLH family protein
Vang10g06720.1bHLH family protein
Vang1160s00010.1bHLH family protein
Vang11g01750.1bHLH family protein
Vang11g03900.1bHLH family protein
Vang11g03970.1bHLH family protein
Vang11g05040.1bHLH family protein
Vang11g05060.1bHLH family protein
Vang11g10340.1bHLH family protein
Vang11g11680.1bHLH family protein
Vang11g12510.1bHLH family protein
Vang11g13300.1bHLH family protein
Vang11g15280.1bHLH family protein
Vang1339s00010.1bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250