PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Vigna angularis
HD-ZIP Family
Species TF ID Description
Vang02g13700.1HD-ZIP family protein
Vang0065s00550.2HD-ZIP family protein
Vang0065s00550.1HD-ZIP family protein
Vang08g02820.1HD-ZIP family protein
Vang08g02820.3HD-ZIP family protein
Vang0057ss00020.1HD-ZIP family protein
Vang0057ss00020.3HD-ZIP family protein
Vang08g02820.2HD-ZIP family protein
Vang0057ss00020.2HD-ZIP family protein
Vang0033ss01740.1HD-ZIP family protein
Vang09g00980.1HD-ZIP family protein
Vang11g10140.1HD-ZIP family protein
Vang02g15370.1HD-ZIP family protein
Vang0497s00080.1HD-ZIP family protein
Vang04g05220.1HD-ZIP family protein
Vang11g05900.1HD-ZIP family protein
Vang07g04940.1HD-ZIP family protein
Vang07g03030.1HD-ZIP family protein
Vang11g04930.1HD-ZIP family protein
Vang08g05160.1HD-ZIP family protein
Vang04g05580.1HD-ZIP family protein
Vang0295s00010.1HD-ZIP family protein
Vang01g18210.1HD-ZIP family protein
Vang0063ss00820.1HD-ZIP family protein
Vang0238s00220.1HD-ZIP family protein
Vang0134s00420.1HD-ZIP family protein
Vang06g20150.1HD-ZIP family protein
Vang03g09030.1HD-ZIP family protein
Vang1570s00010.1HD-ZIP family protein
Vang0022ss03100.1HD-ZIP family protein
Vang0134s00500.1HD-ZIP family protein
Vang02g06660.1HD-ZIP family protein
Vang02g06660.2HD-ZIP family protein
Vang07g00120.1HD-ZIP family protein
Vang11g03040.1HD-ZIP family protein
Vang02g06660.3HD-ZIP family protein
Vang09g06920.1HD-ZIP family protein
Vang11g13110.2HD-ZIP family protein
Vang11g13110.1HD-ZIP family protein
Vang07g03590.2HD-ZIP family protein
Vang0011ss00240.1HD-ZIP family protein
Vang0182s00740.1HD-ZIP family protein
Vang09g02050.1HD-ZIP family protein
Vang0162s00010.1HD-ZIP family protein
Vang0069ss01560.1HD-ZIP family protein
Vang10g00140.1HD-ZIP family protein
Vang0030ss00230.2HD-ZIP family protein
Vang0030ss00230.1HD-ZIP family protein
Vang06g02830.1HD-ZIP family protein
Vang05g10000.1HD-ZIP family protein
Vang02g02830.1HD-ZIP family protein
Vang03g03130.1HD-ZIP family protein
Vang06g04690.1HD-ZIP family protein
Vang10g03470.1HD-ZIP family protein
Vang0114s00150.1HD-ZIP family protein
Vang0032ss00020.1HD-ZIP family protein
Vang03g03030.1HD-ZIP family protein
Vang02g03980.1HD-ZIP family protein
Vang07g08210.1HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401