PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Utricularia gibba
WRKY Family
Species TF ID Description
678293982WRKY family protein
678294505WRKY family protein
678295096WRKY family protein
678296273WRKY family protein
678297148WRKY family protein
678301545WRKY family protein
678302576WRKY family protein
678303220WRKY family protein
678310937WRKY family protein
678313982WRKY family protein
678314388WRKY family protein
678314930WRKY family protein
678317179WRKY family protein
678319760WRKY family protein
678322171WRKY family protein
678325198WRKY family protein
678331795WRKY family protein
678334050WRKY family protein
678336243WRKY family protein
678337636WRKY family protein
678341429WRKY family protein
678343627WRKY family protein
678345503WRKY family protein
678347711WRKY family protein
678350400WRKY family protein
678351859WRKY family protein
678357032WRKY family protein
678359678WRKY family protein
678359899WRKY family protein
678364323WRKY family protein
678365083WRKY family protein
678366561WRKY family protein
678378026WRKY family protein
678378354WRKY family protein
678378606WRKY family protein
678392696WRKY family protein
678392851WRKY family protein
678394474WRKY family protein
678398594WRKY family protein
678400283WRKY family protein
678400617WRKY family protein
678404507WRKY family protein
678405787WRKY family protein
678411797WRKY family protein
678413400WRKY family protein
678416238WRKY family protein
678416473WRKY family protein
678419519WRKY family protein
678420838WRKY family protein
678425870WRKY family protein
678436146WRKY family protein
678442144WRKY family protein
678443342WRKY family protein
678444473WRKY family protein
678445069WRKY family protein
678445944WRKY family protein
678446713WRKY family protein
678447060WRKY family protein
678448673WRKY family protein
678451337WRKY family protein
678451653WRKY family protein
678452482WRKY family protein
678455583WRKY family protein
678456657WRKY family protein
678457803WRKY family protein
678458552WRKY family protein
678459158WRKY family protein
678460914WRKY family protein
678463176WRKY family protein
678463573WRKY family protein
678464136WRKY family protein
678472204WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701