PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Tarenaya hassleriana
bHLH Family
Species TF ID Description
XP_010518919.1bHLH family protein
XP_010519174.1bHLH family protein
XP_010520359.1bHLH family protein
XP_010521172.1bHLH family protein
XP_010521479.1bHLH family protein
XP_010521480.1bHLH family protein
XP_010521720.1bHLH family protein
XP_010522155.1bHLH family protein
XP_010522156.1bHLH family protein
XP_010522215.1bHLH family protein
XP_010522230.1bHLH family protein
XP_010522231.1bHLH family protein
XP_010522232.1bHLH family protein
XP_010522233.1bHLH family protein
XP_010522234.1bHLH family protein
XP_010522235.1bHLH family protein
XP_010522381.1bHLH family protein
XP_010522390.1bHLH family protein
XP_010522399.1bHLH family protein
XP_010522498.1bHLH family protein
XP_010522499.1bHLH family protein
XP_010522703.1bHLH family protein
XP_010522761.1bHLH family protein
XP_010522859.1bHLH family protein
XP_010522878.1bHLH family protein
XP_010522879.1bHLH family protein
XP_010522910.1bHLH family protein
XP_010522924.1bHLH family protein
XP_010522932.1bHLH family protein
XP_010523094.1bHLH family protein
XP_010523095.1bHLH family protein
XP_010523124.1bHLH family protein
XP_010523194.1bHLH family protein
XP_010523351.1bHLH family protein
XP_010523404.1bHLH family protein
XP_010523405.1bHLH family protein
XP_010523814.1bHLH family protein
XP_010523833.1bHLH family protein
XP_010523870.1bHLH family protein
XP_010523871.1bHLH family protein
XP_010524125.1bHLH family protein
XP_010524267.1bHLH family protein
XP_010524295.1bHLH family protein
XP_010524482.1bHLH family protein
XP_010525275.1bHLH family protein
XP_010525344.1bHLH family protein
XP_010525627.1bHLH family protein
XP_010525635.1bHLH family protein
XP_010525742.1bHLH family protein
XP_010525813.1bHLH family protein
XP_010526459.1bHLH family protein
XP_010526460.1bHLH family protein
XP_010526564.1bHLH family protein
XP_010526758.1bHLH family protein
XP_010526883.1bHLH family protein
XP_010526884.1bHLH family protein
XP_010526885.1bHLH family protein
XP_010526886.1bHLH family protein
XP_010526887.1bHLH family protein
XP_010526889.1bHLH family protein
XP_010526890.1bHLH family protein
XP_010527277.1bHLH family protein
XP_010527278.1bHLH family protein
XP_010527427.1bHLH family protein
XP_010527480.1bHLH family protein
XP_010527481.1bHLH family protein
XP_010528040.1bHLH family protein
XP_010528329.1bHLH family protein
XP_010528430.1bHLH family protein
XP_010528431.1bHLH family protein
XP_010528528.1bHLH family protein
XP_010528862.1bHLH family protein
XP_010528939.1bHLH family protein
XP_010528979.1bHLH family protein
XP_010529068.1bHLH family protein
XP_010529849.1bHLH family protein
XP_010530031.1bHLH family protein
XP_010530182.1bHLH family protein
XP_010530401.1bHLH family protein
XP_010530831.1bHLH family protein
XP_010531040.1bHLH family protein
XP_010531245.1bHLH family protein
XP_010531246.1bHLH family protein
XP_010531323.1bHLH family protein
XP_010531324.1bHLH family protein
XP_010531337.1bHLH family protein
XP_010531586.1bHLH family protein
XP_010531653.1bHLH family protein
XP_010531654.1bHLH family protein
XP_010531704.1bHLH family protein
XP_010531809.1bHLH family protein
XP_010532461.1bHLH family protein
XP_010532463.1bHLH family protein
XP_010532469.1bHLH family protein
XP_010532633.1bHLH family protein
XP_010532719.1bHLH family protein
XP_010532793.1bHLH family protein
XP_010534340.1bHLH family protein
XP_010534341.1bHLH family protein
XP_010534342.1bHLH family protein
XP_010534343.1bHLH family protein
XP_010534344.1bHLH family protein
XP_010534345.1bHLH family protein
XP_010534347.1bHLH family protein
XP_010534610.1bHLH family protein
XP_010535200.1bHLH family protein
XP_010535287.1bHLH family protein
XP_010536057.1bHLH family protein
XP_010536058.1bHLH family protein
XP_010536059.1bHLH family protein
XP_010536508.1bHLH family protein
XP_010536509.1bHLH family protein
XP_010536585.1bHLH family protein
XP_010536589.1bHLH family protein
XP_010536590.1bHLH family protein
XP_010536591.1bHLH family protein
XP_010536863.1bHLH family protein
XP_010536888.1bHLH family protein
XP_010536889.1bHLH family protein
XP_010536890.1bHLH family protein
XP_010537121.1bHLH family protein
XP_010537275.1bHLH family protein
XP_010537360.1bHLH family protein
XP_010537453.1bHLH family protein
XP_010537454.1bHLH family protein
XP_010537455.1bHLH family protein
XP_010537647.1bHLH family protein
XP_010538109.1bHLH family protein
XP_010538142.1bHLH family protein
XP_010538143.1bHLH family protein
XP_010538167.1bHLH family protein
XP_010538175.1bHLH family protein
XP_010538184.1bHLH family protein
XP_010538192.1bHLH family protein
XP_010538242.1bHLH family protein
XP_010538366.1bHLH family protein
XP_010538501.1bHLH family protein
XP_010538664.1bHLH family protein
XP_010538684.1bHLH family protein
XP_010539274.1bHLH family protein
XP_010539408.1bHLH family protein
XP_010539409.1bHLH family protein
XP_010539410.1bHLH family protein
XP_010539967.1bHLH family protein
XP_010540284.1bHLH family protein
XP_010540345.1bHLH family protein
XP_010540346.1bHLH family protein
XP_010540348.1bHLH family protein
XP_010540556.1bHLH family protein
XP_010540785.1bHLH family protein
XP_010540787.1bHLH family protein
XP_010541107.1bHLH family protein
XP_010541108.1bHLH family protein
XP_010541171.1bHLH family protein
XP_010541186.1bHLH family protein
XP_010542162.1bHLH family protein
XP_010542163.1bHLH family protein
XP_010542232.1bHLH family protein
XP_010542484.1bHLH family protein
XP_010542771.1bHLH family protein
XP_010543057.1bHLH family protein
XP_010543098.1bHLH family protein
XP_010543164.1bHLH family protein
XP_010543534.1bHLH family protein
XP_010543536.1bHLH family protein
XP_010543658.1bHLH family protein
XP_010543882.1bHLH family protein
XP_010544015.1bHLH family protein
XP_010544016.1bHLH family protein
XP_010544018.1bHLH family protein
XP_010544019.1bHLH family protein
XP_010544020.1bHLH family protein
XP_010544021.1bHLH family protein
XP_010544022.1bHLH family protein
XP_010544032.1bHLH family protein
XP_010544248.1bHLH family protein
XP_010544250.1bHLH family protein
XP_010544844.1bHLH family protein
XP_010544881.1bHLH family protein
XP_010544882.1bHLH family protein
XP_010544921.1bHLH family protein
XP_010544923.1bHLH family protein
XP_010545177.1bHLH family protein
XP_010545555.1bHLH family protein
XP_010545556.1bHLH family protein
XP_010545557.1bHLH family protein
XP_010545729.1bHLH family protein
XP_010545873.1bHLH family protein
XP_010546046.1bHLH family protein
XP_010546047.1bHLH family protein
XP_010546054.1bHLH family protein
XP_010546079.1bHLH family protein
XP_010546170.1bHLH family protein
XP_010546220.1bHLH family protein
XP_010546221.1bHLH family protein
XP_010546222.1bHLH family protein
XP_010546223.1bHLH family protein
XP_010546225.1bHLH family protein
XP_010546834.1bHLH family protein
XP_010546964.1bHLH family protein
XP_010546966.1bHLH family protein
XP_010547064.1bHLH family protein
XP_010547074.1bHLH family protein
XP_010547083.1bHLH family protein
XP_010547092.1bHLH family protein
XP_010547134.1bHLH family protein
XP_010547247.1bHLH family protein
XP_010547248.1bHLH family protein
XP_010547249.1bHLH family protein
XP_010547446.1bHLH family protein
XP_010547518.1bHLH family protein
XP_010547798.1bHLH family protein
XP_010547799.1bHLH family protein
XP_010547809.1bHLH family protein
XP_010547816.1bHLH family protein
XP_010547824.1bHLH family protein
XP_010547827.1bHLH family protein
XP_010547953.1bHLH family protein
XP_010548100.1bHLH family protein
XP_010548101.1bHLH family protein
XP_010548115.1bHLH family protein
XP_010548116.1bHLH family protein
XP_010548267.1bHLH family protein
XP_010548276.1bHLH family protein
XP_010548277.1bHLH family protein
XP_010548278.1bHLH family protein
XP_010548279.1bHLH family protein
XP_010548280.1bHLH family protein
XP_010548281.1bHLH family protein
XP_010548282.1bHLH family protein
XP_010548286.1bHLH family protein
XP_010548292.1bHLH family protein
XP_010548320.1bHLH family protein
XP_010548321.1bHLH family protein
XP_010548419.1bHLH family protein
XP_010548420.1bHLH family protein
XP_010548502.1bHLH family protein
XP_010548590.1bHLH family protein
XP_010548597.1bHLH family protein
XP_010548649.1bHLH family protein
XP_010548650.1bHLH family protein
XP_010548672.1bHLH family protein
XP_010548673.1bHLH family protein
XP_010548674.1bHLH family protein
XP_010548675.1bHLH family protein
XP_010548709.1bHLH family protein
XP_010548710.1bHLH family protein
XP_010548711.1bHLH family protein
XP_010548712.1bHLH family protein
XP_010548713.1bHLH family protein
XP_010548714.1bHLH family protein
XP_010548717.1bHLH family protein
XP_010548842.1bHLH family protein
XP_010548843.1bHLH family protein
XP_010548846.1bHLH family protein
XP_010549185.1bHLH family protein
XP_010549189.1bHLH family protein
XP_010549193.1bHLH family protein
XP_010549473.1bHLH family protein
XP_010550064.1bHLH family protein
XP_010550611.1bHLH family protein
XP_010551310.1bHLH family protein
XP_010551346.1bHLH family protein
XP_010551351.1bHLH family protein
XP_010551523.1bHLH family protein
XP_010551862.1bHLH family protein
XP_010551931.1bHLH family protein
XP_010552022.1bHLH family protein
XP_010552489.1bHLH family protein
XP_010552542.1bHLH family protein
XP_010552543.1bHLH family protein
XP_010552544.1bHLH family protein
XP_010552545.1bHLH family protein
XP_010552546.1bHLH family protein
XP_010552588.1bHLH family protein
XP_010552794.1bHLH family protein
XP_010552795.1bHLH family protein
XP_010552796.1bHLH family protein
XP_010553329.1bHLH family protein
XP_010553488.1bHLH family protein
XP_010553516.1bHLH family protein
XP_010553518.1bHLH family protein
XP_010553519.1bHLH family protein
XP_010553649.1bHLH family protein
XP_010553662.1bHLH family protein
XP_010553663.1bHLH family protein
XP_010553664.1bHLH family protein
XP_010553700.1bHLH family protein
XP_010553759.1bHLH family protein
XP_010553760.1bHLH family protein
XP_010553947.1bHLH family protein
XP_010553948.1bHLH family protein
XP_010553949.1bHLH family protein
XP_010554134.1bHLH family protein
XP_010554135.1bHLH family protein
XP_010554136.1bHLH family protein
XP_010554137.1bHLH family protein
XP_010554138.1bHLH family protein
XP_010554140.1bHLH family protein
XP_010554141.1bHLH family protein
XP_010554450.1bHLH family protein
XP_010554754.1bHLH family protein
XP_010554771.1bHLH family protein
XP_010554849.1bHLH family protein
XP_010554850.1bHLH family protein
XP_010554981.1bHLH family protein
XP_010555404.1bHLH family protein
XP_010555405.1bHLH family protein
XP_010555406.1bHLH family protein
XP_010555430.1bHLH family protein
XP_010555452.1bHLH family protein
XP_010555784.1bHLH family protein
XP_010556002.1bHLH family protein
XP_010556003.1bHLH family protein
XP_010556004.1bHLH family protein
XP_010556387.1bHLH family protein
XP_010556447.1bHLH family protein
XP_010556598.1bHLH family protein
XP_010556617.1bHLH family protein
XP_010556634.1bHLH family protein
XP_010556635.1bHLH family protein
XP_010556669.1bHLH family protein
XP_010556670.1bHLH family protein
XP_010556671.1bHLH family protein
XP_010556765.1bHLH family protein
XP_010557357.1bHLH family protein
XP_010557784.1bHLH family protein
XP_010558577.1bHLH family protein
XP_010558851.1bHLH family protein
XP_010559123.1bHLH family protein
XP_010559146.1bHLH family protein
XP_010559147.1bHLH family protein
XP_010559148.1bHLH family protein
XP_010559298.1bHLH family protein
XP_010559309.1bHLH family protein
bHLH Family Introduction

The basic/helix-loop-helix (bHLH) proteins are a superfamily of transcription factors that have been well characterized in nonplant eukaryotes, especially in mammalian systems, in which considerable structural, functional, and phylogenetic analyses have been performed. The data indicate that bHLH proteins are important regulatory components in transcriptional networks in these systems, controlling a diversity of processes from cell proliferation to cell lineage establishment.

This family is defined by the bHLH signature domain, which consists of 60 amino acids with two functionally distinct regions. The basic region, located at the N-terminal end of the domain, is involved in DNA binding and consists of 15 amino acids with a high number of basic residues. The HLH region, at the C-terminal end, functions as a dimerization domain and is constituted mainly of hydrophobic residues that form two amphipathic -helices separated by a loop region of variable sequence and length. Outside of the conserved bHLH domain, these proteins exhibit considerable sequence divergence. Cocrystal structural analysis has shown that the interaction between the HLH regions of two separate polypeptides leads to the formation of homodimers and/or heterodimers and that the basic region of each partner binds to half of the DNA recognition sequence. Some bHLH proteins form homodimers or restrict their heterodimerization activity to closely related members of the family. On the other hand, some can form heterodimers with one or several different partners.

The core DNA sequence motif recognized by the bHLH proteins is a consensus hexanucleotide sequence known as the E-box (5'-CANNTG-3'). There are different types of E-boxes, depending on the identity of the two central bases. One of the most common is the palindromic G-box (5'-CACGTG-3'). Certain conserved amino acids within the basic region of the protein provide recognition of the core consensus site, whereas other residues in the domain dictate specificity for a given type of E-box . In addition, flanking nucleotides outside of the hexanucleotide core have been shown to play a role in binding specificity, and there is evidence that a loop residue in the protein plays a role in DNA binding through elements that lie outside of the core recognition sequence.

Toledo-Ortiz G, Huq E, Quail PH.
The Arabidopsis basic/helix-loop-helix transcription factor family.
Plant Cell. 2003 Aug;15(8):1749-70
PMID: 12897250