PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Tarenaya hassleriana
E2F/DP Family
Species TF ID Description
XP_010520454.1E2F/DP family protein
XP_010520455.1E2F/DP family protein
XP_010520457.1E2F/DP family protein
XP_010520458.1E2F/DP family protein
XP_010520690.1E2F/DP family protein
XP_010520691.1E2F/DP family protein
XP_010527132.1E2F/DP family protein
XP_010527175.1E2F/DP family protein
XP_010530521.1E2F/DP family protein
XP_010535712.1E2F/DP family protein
XP_010539053.1E2F/DP family protein
XP_010543316.1E2F/DP family protein
XP_010543317.1E2F/DP family protein
XP_010543412.1E2F/DP family protein
XP_010543413.1E2F/DP family protein
XP_010543414.1E2F/DP family protein
XP_010543415.1E2F/DP family protein
XP_010543416.1E2F/DP family protein
XP_010543417.1E2F/DP family protein
XP_010543418.1E2F/DP family protein
XP_010543419.1E2F/DP family protein
XP_010543420.1E2F/DP family protein
XP_010543421.1E2F/DP family protein
XP_010543422.1E2F/DP family protein
XP_010543424.1E2F/DP family protein
XP_010543425.1E2F/DP family protein
XP_010543426.1E2F/DP family protein
XP_010543427.1E2F/DP family protein
XP_010546013.1E2F/DP family protein
XP_010550096.1E2F/DP family protein
XP_010550672.1E2F/DP family protein
XP_010553035.1E2F/DP family protein
XP_010553036.1E2F/DP family protein
XP_010553037.1E2F/DP family protein
XP_010553038.1E2F/DP family protein
XP_010553039.1E2F/DP family protein
XP_010553040.1E2F/DP family protein
XP_010553041.1E2F/DP family protein
XP_010557435.1E2F/DP family protein
XP_010557436.1E2F/DP family protein
XP_010558176.1E2F/DP family protein
E2F/DP Family Introduction

E2F transcription factors are a family of proteins that share a related DNA-binding domain and that bind to overlapping sets of target promoters. Most E2F proteins associate with a DP protein and form heterodimeric complexes that bind to DNA in a sequence-specific manner. E2F proteins control the temporal expression of genes that are needed for multiple processes during the cell cycle. Consequently, the level of E2F-dependent transcription is important for cell proliferation.

Different types of E2F complexes either activate or repress transcription. E2F repressor complexes suppress the transcription of their targets in quiescent cells, in differentiated cells and during the G1 phase of the cell cycle. When cells enter the cell cycle and proliferate, these repressors are disrupted and/or replaced by activator forms of E2F that promote gene expression.

van den Heuvel S, Dyson NJ.
Conserved functions of the pRB and E2F families.
Nat Rev Mol Cell Biol, 2008. 9(9): p. 713-24.
PMID: 18719710