PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Theobroma cacao
FAR1 Family
Species TF ID Description
Thecc1EG002030t1FAR1 family protein
Thecc1EG002031t1FAR1 family protein
Thecc1EG002031t2FAR1 family protein
Thecc1EG002031t3FAR1 family protein
Thecc1EG002031t4FAR1 family protein
Thecc1EG002031t5FAR1 family protein
Thecc1EG002031t6FAR1 family protein
Thecc1EG002031t7FAR1 family protein
Thecc1EG002031t8FAR1 family protein
Thecc1EG002647t1FAR1 family protein
Thecc1EG002647t2FAR1 family protein
Thecc1EG002653t1FAR1 family protein
Thecc1EG002653t2FAR1 family protein
Thecc1EG002654t1FAR1 family protein
Thecc1EG002654t2FAR1 family protein
Thecc1EG002654t3FAR1 family protein
Thecc1EG002654t4FAR1 family protein
Thecc1EG002654t5FAR1 family protein
Thecc1EG002654t6FAR1 family protein
Thecc1EG002654t7FAR1 family protein
Thecc1EG006022t1FAR1 family protein
Thecc1EG006022t2FAR1 family protein
Thecc1EG006022t3FAR1 family protein
Thecc1EG007052t1FAR1 family protein
Thecc1EG007609t1FAR1 family protein
Thecc1EG011369t1FAR1 family protein
Thecc1EG013043t1FAR1 family protein
Thecc1EG013043t10FAR1 family protein
Thecc1EG013043t2FAR1 family protein
Thecc1EG013043t5FAR1 family protein
Thecc1EG013043t7FAR1 family protein
Thecc1EG013043t8FAR1 family protein
Thecc1EG015107t1FAR1 family protein
Thecc1EG015107t2FAR1 family protein
Thecc1EG015107t3FAR1 family protein
Thecc1EG017061t1FAR1 family protein
Thecc1EG017061t2FAR1 family protein
Thecc1EG017493t1FAR1 family protein
Thecc1EG018711t1FAR1 family protein
Thecc1EG020020t1FAR1 family protein
Thecc1EG020030t1FAR1 family protein
Thecc1EG020030t2FAR1 family protein
Thecc1EG020030t3FAR1 family protein
Thecc1EG020030t4FAR1 family protein
Thecc1EG020031t1FAR1 family protein
Thecc1EG020033t1FAR1 family protein
Thecc1EG020033t2FAR1 family protein
Thecc1EG020034t1FAR1 family protein
Thecc1EG020035t1FAR1 family protein
Thecc1EG020038t1FAR1 family protein
Thecc1EG020038t2FAR1 family protein
Thecc1EG020251t1FAR1 family protein
Thecc1EG020251t2FAR1 family protein
Thecc1EG021065t1FAR1 family protein
Thecc1EG021065t2FAR1 family protein
Thecc1EG021065t3FAR1 family protein
Thecc1EG021310t1FAR1 family protein
Thecc1EG021310t2FAR1 family protein
Thecc1EG021310t3FAR1 family protein
Thecc1EG025116t1FAR1 family protein
Thecc1EG026958t1FAR1 family protein
Thecc1EG027270t1FAR1 family protein
Thecc1EG027271t1FAR1 family protein
Thecc1EG027271t2FAR1 family protein
Thecc1EG027272t1FAR1 family protein
Thecc1EG030416t1FAR1 family protein
Thecc1EG030416t2FAR1 family protein
Thecc1EG030416t3FAR1 family protein
Thecc1EG030416t4FAR1 family protein
Thecc1EG030416t5FAR1 family protein
Thecc1EG030416t6FAR1 family protein
Thecc1EG034806t1FAR1 family protein
Thecc1EG034806t2FAR1 family protein
Thecc1EG036972t1FAR1 family protein
Thecc1EG036972t2FAR1 family protein
Thecc1EG036972t3FAR1 family protein
Thecc1EG040565t1FAR1 family protein
Thecc1EG040565t2FAR1 family protein
Thecc1EG040565t3FAR1 family protein
Thecc1EG041141t1FAR1 family protein
Thecc1EG042009t1FAR1 family protein
Thecc1EG042009t2FAR1 family protein
Thecc1EG042009t3FAR1 family protein
Thecc1EG042009t4FAR1 family protein
Thecc1EG042009t5FAR1 family protein
Thecc1EG042009t6FAR1 family protein
Thecc1EG042009t7FAR1 family protein
Thecc1EG044608t1FAR1 family protein
Thecc1EG044608t2FAR1 family protein
Thecc1EG044608t3FAR1 family protein
Thecc1EG044608t4FAR1 family protein
Thecc1EG046723t1FAR1 family protein
FAR1 Family Introduction

We show that Arabidopsis FHY3 and FAR1, which encode two proteins related to Mutator-like transposases, act together to modulate phyA signaling by directly activating the transcription of FHY1 and FHL, whose products are essential for light-induced phyA nuclear accumulation and subsequent light responses. FHY3 and FAR1 have separable DNA binding and transcriptional activation domains that are highly conserved in Mutator-like transposases. Further, expression of FHY3 and FAR1 is negatively regulated by phyA signaling. We propose that FHY3 and FAR1 represent transcription factors that have been co-opted from an ancient Mutator-like transposase(s) to modulate phyA-signaling homeostasis in higher plants.

We next used a yeast one-hybrid assay to delineate the DNA sequences to which FHY3 and FAR1 bind. GAD-FHY3 or GAD-FAR1 fusion proteins (GAD, GAL4 transcriptional activation domain), but not GAD alone, activated the LacZ reporter genes driven by the FHY1 and FHL promoters. Deletion analysis narrowed down the FHY3/FAR1 binding site to a 39-bp promoter subfragment located on the "a" fragment for both FHY1 and FHL. Notably, these subfragments share a stretch of consensus sequence, 5'-TTCACGCGCC-3'. Mutating the core sequence "CACGCGC" of this motif (m2 and m3 for FHY1, m5 for FHL) abolished the reporter gene activation by both GAD-FHY3 and GAD-FAR1. Mutating the flanking sequences (m1 and m4) did not obviously affect the reporter gene activation by GAD-FAR1, but clearly reduced activation by GAD-FHY3. Thus, "CACGCGC" likely defines a cis-element that confers specific binding for FHY3 and FAR1 and is named FBS for FHY3-FAR1 binding site.

Lin R, Ding L, Casola C, Ripoll DR, Feschotte C, Wang H.
Transposase-derived transcription factors regulate light signaling in Arabidopsis.
Science, 2007. 318(5854): p. 1302-5.
PMID: 18033885