PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Triticum aestivum
SBP Family
Species TF ID Description
Traes_1AL_C921492AA.1SBP family protein
Traes_1BL_8709BB152.2SBP family protein
Traes_1DL_93BCED372.2SBP family protein
Traes_2AL_054360BDD.1SBP family protein
Traes_2AL_B45245746.2SBP family protein
Traes_2AS_C2A4AFE6F.1SBP family protein
Traes_2BL_0978E2D14.1SBP family protein
Traes_2BL_46BA39C7B.2SBP family protein
Traes_2BL_69E6AB6D1.2SBP family protein
Traes_2BS_186EA570A.1SBP family protein
Traes_4AL_5062917C4.1SBP family protein
Traes_5AL_637B13721.2SBP family protein
Traes_5BL_3503725F1.2SBP family protein
Traes_5BL_96D5EA4EE.1SBP family protein
Traes_5BL_96FDFC152.1SBP family protein
Traes_5DL_1272B4BAC.1SBP family protein
Traes_5DL_3CDCC5DFF.2SBP family protein
Traes_5DL_C588E74B5.1SBP family protein
Traes_6AS_32A35158A.1SBP family protein
Traes_6AS_99C6A3B0B.2SBP family protein
Traes_6BS_F50663DF7.1SBP family protein
Traes_6DS_7B1596298.1SBP family protein
Traes_6DS_C4D93239C.1SBP family protein
Traes_7AL_03E14BABE.1SBP family protein
Traes_7AS_0F019FB93.2SBP family protein
Traes_7AS_F2DF86C49.2SBP family protein
Traes_7AS_FB2A769B5.1SBP family protein
Traes_7BL_C4BA39104.1SBP family protein
Traes_7BS_1542EA53A.1SBP family protein
Traes_7BS_63CE69B1D.1SBP family protein
Traes_7BS_7ACA0B10A.2SBP family protein
Traes_7DL_1957A97EC.1SBP family protein
Traes_7DL_2D8356B05.1SBP family protein
Traes_7DL_ED348696E.1SBP family protein
Traes_7DS_3880F0FD0.1SBP family protein
Traes_7DS_AB399594E.2SBP family protein
Traes_7DS_E2A582546.1SBP family protein
SBP Family Introduction

SQUAMOSA promoter binding proteins (SBPs) form a major family of plant-specific transcription factors related to flower development. Although SBPs are heterogeneous in primary structure, they share a highly conserved DNA-binding domain (DBD) that has been suggested to be zinc binding. Here we report the NMR solution structures of DBDs of two SBPs of Arabidopsis thaliana, SPL4 and SPL7. The two share essentially the same structural features. Each structure contains two zinc-binding sites consisting of eight Cys or His residues in a Cys3HisCys2HisCys or Cys6HisCys sequence motif in which the first four residues coordinate to one zinc and the last four coordinate to the other. These structures are dissimilar to other known zinc-binding structures, and thus represent a novel type of zinc-binding motif. The electrostatic profile on the surface suggested that a continuous region, including all the conserved basic residues, is involved in the DNA binding, the mode of which is likely to be novel as well.

Yamasaki K, Kigawa T, Inoue M, Tateno M, Yamasaki T, Yabuki T, Aoki M, Seki E, Matsuda T, Nunokawa E, Ishizuka Y, Terada T, Shirouzu M, Osanai T, Tanaka A, Seki M, Shinozaki K, Yokoyama S.
A novel zinc-binding motif revealed by solution structures of DNA-binding domains of Arabidopsis SBP-family transcription factors
J Mol Biol. 2004 Mar 12;337(1):49-63.
PMID: 15001351

SBP-box genes were first characterized as SQUAMOSA promoter binding proteins (SBPs) to regulate the expression of MADS-box genes in early flower development of A. majus (Klein et al., 1996). Since then, SBP-box genes have been identified in many plants including green alga, moss, silver birch, A. majus, Arabidopsis and maize. They play critical roles in regulating flower and fruit development as well as other physiological processes ([Moreno et al., 1997],[Eriksson et al., 2004], [Lannenpaa et al., 2004], [Arazi et al., 2005] and [Kropat et al., 2005]). It has been reported that Arabidopsis SPL3, SPL8 and SPL14 involves in flowering, sporogenesis, GA signaling and toxin resistance ([Cardon et al., 1997], [Unte et al., 2003], [Stone et al., 2005] and [Zhang et al., 2006]) while maize tga1 and tomato LeSPL-CNR affect fruit development ([Wang et al., 2005a] and [Manning et al., 2006]).

SBP-box genes encode proteins sharing a conserved DNA-binding domain of 79 amino acid residues. It has been proved that the DNA-binding domain of SBP-box genes is necessary and sufficient to bind to a palindromic GTAC core motif ([Klein et al., 1996], [Cardon et al., 1997], [Cardon et al., 1999], [Lannenpaa et al., 2004] and [Birkenbihl et al., 2005]). Studies on the NMR solution structure of the fragment of Arabidopsis SPL4 and SPL7 revealed that the DNA-binding domain of SBPs consisted of two separate zinc-binding sites. One zinc finger is C3H or C4 and the other is C2HC (Yamasaki et al., 2004 K. Yamasaki et al.,).

Guo AY, Zhu QH, Gu X, Ge S, Yang J, Luo J.
Genome-wide identification and evolutionary analysis of the plant specific SBP-box transcription factor family.
Gene. 2008 Jul 15;418(1-2):1-8.
PMID: 18495384