PlantTFDB
Plant Transcription Factor Database
v4.0
Previous version: v1.0, v2.0, v3.0
Triticum aestivum
HD-ZIP Family
Species TF ID Description
Traes_5BL_5DE02D63E.1HD-ZIP family protein
Traes_6DL_FF4C8C4AB.1HD-ZIP family protein
Traes_6AL_36AB0312C.1HD-ZIP family protein
Traes_4DL_88ABAD6C0.1HD-ZIP family protein
Traes_4BL_ECD20BE67.1HD-ZIP family protein
Traes_4AL_99A941299.1HD-ZIP family protein
Traes_5BL_4A3874701.1HD-ZIP family protein
Traes_4BL_78DD63002.1HD-ZIP family protein
Traes_2AL_EF9549D16.1HD-ZIP family protein
Traes_2DL_67F1183B2.1HD-ZIP family protein
Traes_4BL_BE3E058A6.1HD-ZIP family protein
Traes_2BL_B69300543.1HD-ZIP family protein
Traes_4AL_822582A19.1HD-ZIP family protein
Traes_4AS_F04DD4409.1HD-ZIP family protein
Traes_5BL_028D02DF6.1HD-ZIP family protein
Traes_5BL_9C32B27E2.1HD-ZIP family protein
Traes_5DL_96F9EED93.2HD-ZIP family protein
TRAES3BF026400090CFD_t1HD-ZIP family protein
TRAES3BF043500070CFD_t1HD-ZIP family protein
Traes_1BL_BCA60D8B6.2HD-ZIP family protein
Traes_3DS_7CCB5ECD2.1HD-ZIP family protein
Traes_2DS_20F748657.2HD-ZIP family protein
Traes_2BS_BD0ED621D.2HD-ZIP family protein
Traes_2BL_02479C76A.1HD-ZIP family protein
Traes_6DS_17B737547.1HD-ZIP family protein
Traes_6DS_F00EB2E01.1HD-ZIP family protein
Traes_6DS_F00EB2E011.1HD-ZIP family protein
Traes_6AS_3E534A2C1.1HD-ZIP family protein
Traes_7DL_2FE5181AF.1HD-ZIP family protein
Traes_4BL_BE10705D5.2HD-ZIP family protein
Traes_4DL_4798D0BBD.1HD-ZIP family protein
Traes_6DS_D281B7D32.1HD-ZIP family protein
Traes_4AS_1EA23DE08.1HD-ZIP family protein
Traes_2AL_CC3E5591E.1HD-ZIP family protein
Traes_2BL_419CEED79.1HD-ZIP family protein
Traes_2BL_419CEED791.1HD-ZIP family protein
Traes_7AL_44206BE21.1HD-ZIP family protein
Traes_3AL_D6813CBDE.1HD-ZIP family protein
Traes_2AL_BFB0C6D4C.1HD-ZIP family protein
Traes_1AL_1444D461A.1HD-ZIP family protein
Traes_1AL_1444D461A1.1HD-ZIP family protein
Traes_4DL_F6ADA799C.1HD-ZIP family protein
Traes_3DL_37D040907.1HD-ZIP family protein
Traes_2BL_1F5DBD5D5.1HD-ZIP family protein
Traes_2AL_48B239DD6.1HD-ZIP family protein
TRAES3BF023000040CFD_t1HD-ZIP family protein
Traes_5DL_8F7AC72B0.2HD-ZIP family protein
TRAES3BF073700090CFD_t1HD-ZIP family protein
Traes_2AL_C00552444.1HD-ZIP family protein
Traes_6DL_8D95F127B.1HD-ZIP family protein
Traes_7DL_57A842933.2HD-ZIP family protein
Traes_5BS_360DD5644.1HD-ZIP family protein
Traes_5DS_50846FD0C.1HD-ZIP family protein
Traes_1BL_43408C9B0.2HD-ZIP family protein
Traes_1AL_0BE456AC0.1HD-ZIP family protein
Traes_4DL_F064084A9.2HD-ZIP family protein
Traes_5AL_A5234EC05.1HD-ZIP family protein
Traes_6DL_D722B6E13.1HD-ZIP family protein
TRAES3BF075200070CFD_t1HD-ZIP family protein
Traes_5AL_4F083B77E.1HD-ZIP family protein
Traes_4BS_C74B4B7BA.1HD-ZIP family protein
Traes_3DL_8AAFB7B06.1HD-ZIP family protein
HD-ZIP Family Introduction

A homeobox (HB) encodes a protein domain, the homeodomain (HD), which is a conserved 60-amino acid motif present in transcription factors found in all the eukaryotic organisms. This 60-amino acid sequence folds into a characteristic three-helix structure that is able to interact specifically with DNA. Most HDs are able to bind DNA as monomers with high affinity, through interactions made by helix III (the so-called recognition helix) and a disordered N-terminal arm located beyond helix I. The high degree of conservation of this type of domain among diverse proteins from different kingdoms indicates that this structure is crucial to maintain the HD functionality and that the role played by this domain is vital.

Members of the HD-Zip family have a leucine zipper motif (LZ) immediately downstream of the HD. The two motifs are present in transcription factors found in species belonging to other eukaryotic kingdoms, but their association in a single protein is unique to plants. The HD is responsible for the specific binding to DNA, whereas LZ acts as a dimerization motif. HD-Zip proteins bind to DNA as dimers, and the absence of LZ absolutely abolishes their binding ability, which indicates that the relative orientation of the monomers, driven by this motif, is crucial for an efficient recognition of DNA.

Ariel FD, Manavella PA, Dezar CA, Chan RL.
The true story of the HD-Zip family.
Trends Plant Sci, 2007. 12(9): p. 419-26.
PMID: 17698401