PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
Previous version: v3.0 v4.0
Spirodela polyrhiza
WRKY Family
Species TF ID Description
Spipo0G0100800WRKY family protein
Spipo0G0124900WRKY family protein
Spipo0G0131300WRKY family protein
Spipo0G0147900WRKY family protein
Spipo0G0155800WRKY family protein
Spipo0G0189900WRKY family protein
Spipo10G0008000WRKY family protein
Spipo10G0014600WRKY family protein
Spipo12G0000800WRKY family protein
Spipo12G0044700WRKY family protein
Spipo12G0045200WRKY family protein
Spipo12G0058600WRKY family protein
Spipo13G0050700WRKY family protein
Spipo14G0008700WRKY family protein
Spipo15G0023900WRKY family protein
Spipo18G0011000WRKY family protein
Spipo21G0015100WRKY family protein
Spipo21G0020000WRKY family protein
Spipo21G0020400WRKY family protein
Spipo23G0030300WRKY family protein
Spipo23G0043000WRKY family protein
Spipo24G0008400WRKY family protein
Spipo25G0001100WRKY family protein
Spipo26G0007100WRKY family protein
Spipo27G0009900WRKY family protein
Spipo28G0011500WRKY family protein
Spipo28G0021800WRKY family protein
Spipo29G0013300WRKY family protein
Spipo29G0015400WRKY family protein
Spipo2G0057900WRKY family protein
Spipo2G0076200WRKY family protein
Spipo3G0006000WRKY family protein
Spipo3G0080100WRKY family protein
Spipo3G0092900WRKY family protein
Spipo4G0043400WRKY family protein
Spipo5G0003700WRKY family protein
Spipo5G0018600WRKY family protein
Spipo6G0062100WRKY family protein
Spipo8G0022800WRKY family protein
Spipo8G0045500WRKY family protein
Spipo8G0063100WRKY family protein
Spipo8G0067500WRKY family protein
Spipo9G0018900WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701